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ChemicalBook >> CAS DataBase List >>2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chloro-phenyl]carbamoyl]ben zamide

2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chloro-phenyl]carbamoyl]ben zamide

2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chloro-phenyl]carbamoyl]ben zamide Structure
2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chloro-phenyl]carbamoyl]ben zamide structure
CAS No.
134742-26-0
Chemical Name:
2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chloro-phenyl]carbamoyl]ben zamide
Synonyms
NSC639828;2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chloro-phenyl]carbamoyl]ben zamide;Benzamide, 2-amino-N-[[[4-[(5-bromo-2-pyrimidinyl)oxy]-3-chlorophenyl]amino]carbonyl]-
CBNumber:
CB11256658
Molecular Formula:
C18H13BrClN5O3
Molecular Weight:
462.68
MDL Number:
MOL File:
134742-26-0.mol
Last updated:2024-07-02 08:54:59
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2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chloro-phenyl]carbamoyl]ben zamide Properties

storage temp. -20°C, protect from light
solubility DMSO : 100 mg/mL (216.13 mM; Need ultrasonic)
form Solid
color Light yellow to green yellow

2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chloro-phenyl]carbamoyl]ben zamide Chemical Properties,Uses,Production

Biological Activity

NSC639828 is a potent inhibitor of DNA polymerase α with an IC50 of 70 μM. NSC639828 has high antitumor activity. NSC639828 has the potential for researching cancer disease[1].

References

[1]. Abdel-Aziz W, et al. Effect of novel benzoylphenylurea derivatives on DNA polymerase alpha activity using the synthesome-based in vitro model system. Invest New Drugs. 2003;21(4):421-428.

2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chloro-phenyl]carbamoyl]ben zamide Preparation Products And Raw materials

Raw materials

Preparation Products

2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chloro-phenyl]carbamoyl]ben zamide Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 4009686088 3193328036@qq.com China 29795 68
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 28118 58
Supplier Advantage
Aladdin Scientific 		58
Beijing Solarbio Science & Tecnology Co., Ltd. 68
TargetMol Chemicals Inc. 58
2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chloro-phenyl]carbamoyl]ben zamide Benzamide, 2-amino-N-[[[4-[(5-bromo-2-pyrimidinyl)oxy]-3-chlorophenyl]amino]carbonyl]- NSC639828 134742-26-0 C18H13BrClN5O3