ChemicalBook >> CAS DataBase List >>S-3226
S-3226
- CAS No.
- 215183-03-2
- Chemical Name:
- S-3226
- Synonyms
- S-3226;3,3′-(4-Methyl-1,2-phenylene)bis(N-amidinomethacrylamide);N-carbamimidoyl-3-{2-[2-(carbamimidoylcarbamoyl)-2-methyleth-1-en-1-yl]-5-methylphenyl}-2-methylprop-2-enamide
- CBNumber:
- CB113341216
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Last updated:2025-01-27 09:38:02
S-3226 Chemical Properties,Uses,Production
Biological Activity
S3226 is a potent and selective NHE3 (NHE-3) inhibitor (IC50 = 20 nM/human NHE3, 3.6 μM/human NHE1, 80 μM/rabbit NHE2) for studying NHE3 physiological as well as pathophysiological roles in kidney and gastrointestinal disorders in vitro and in animal models in vivo.', 'S3226 is also known as {3-[2-(3-guanidino-2-methyl-3-oxo-propenyl)-5-methyl-phenyl]-N-isopropylidene-2-methyl-acrylamide dihydro-chloride}. S3226 is used to explore the physiological and pathophysiological functions of sodium-hydrogen exchanger 3 (NHE3) in animal models. It is a bismethacryloyl guanidine derivative.
S-3226 Preparation Products And Raw materials
Raw materials
Preparation Products
S-3226 Suppliers
Global( 1)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Merck KGaA | (+86) 21 2033 8288 | sigmaname@qq.com | CHINA | 292394 | 58 |
Supplier | Advantage |
---|---|
Merck KGaA | 58 |
3,3′-(4-Methyl-1,2-phenylene)bis(N-amidinomethacrylamide)
N-carbamimidoyl-3-{2-[2-(carbamimidoylcarbamoyl)-2-methyleth-1-en-1-yl]-5-methylphenyl}-2-methylprop-2-enamide
S-3226
215183-03-2