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Ethylenediamines

CAS No.
Chemical Name:
Ethylenediamines
Synonyms
Ethylenediamines
CBNumber:
CB11400129
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2024-03-19 15:37:51

Ethylenediamines Chemical Properties,Uses,Production

Description

In 1942, phenbenzamine was introduced as the first clinically useful antihistamine .

Synthesis

Three different methods of synthesizing ethylenediamines are widely used :
1) Reaction of tertiary chloroethylamines with secondary amines in the presence of a base, e.g., NaH, NaNH2, NaOC2H5, or KOH.
2) Alkylation of secondary amines, such as N- (2-dimethylaminoethyl)aniline with benzyl chlorides in the presence of a strong base.
3) Reaction of reactive heterocyclic halogen compounds, such as 2-bromopyridine with secondary amines, such as N-(2-dimethylaminoethyl)- aniline, also in the presence of a strong base.

Ethylenediamines Preparation Products And Raw materials

Raw materials

Preparation Products

Ethylenediamines