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4-NITROQUINOLINE N-OXIDE

CAS No.
56-57-5
Chemical Name:
4-NITROQUINOLINE N-OXIDE
Synonyms
NQO;NQNO;4-nqo;4-NQNO;nitrochin;N-(4-Nitrobenz;Nitroquinolineoxide;TIMTEC-BB SBB006266;4-nitrochinolinn-oxid;4-nitroquinolineoxide
CBNumber:
CB1150485
Molecular Formula:
C9H6N2O3
Molecular Weight:
190.16
MDL Number:
MFCD00006738
MOL File:
56-57-5.mol
MSDS File:
SDS
Last updated:2024-11-19 23:02:33

4-NITROQUINOLINE N-OXIDE Properties

Melting point 154-156 °C(lit.)
Boiling point 325.64°C (rough estimate)
Density 1.42
refractive index 1.5570 (estimate)
storage temp. -20°C
solubility acetone: clear to hazy
pka -1.83±0.10(Predicted)
form Crystalline Solid
color yellow to brown
BRN 165756
Stability Stable. Hygroscopic, light-sensitive. Incompatible with strong oxidizing agents.
InChIKey YHQDZJICGQWFHK-UHFFFAOYSA-N
CAS DataBase Reference 56-57-5(CAS DataBase Reference)
EWG's Food Scores 1
NCI Dictionary of Cancer Terms 4-nitroquinoline 1-oxide; 4-NQO
FDA UNII X5081510EV
EPA Substance Registry System 4-Nitroquinoline 1-oxide (56-57-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Danger
Hazard statements  H350
Precautionary statements  P201-P308+P313
Hazard Codes  T
Risk Statements  45-68-40-20/21/22
Safety Statements  53-45-36/37-22
RIDADR  2811
WGK Germany  3
RTECS  VC2100000
HazardClass  6.1
PackingGroup  II
HS Code  29339900
Toxicity LD50 intraperitoneal in mouse: 190mg/kg
NFPA 704
1
0 1

4-NITROQUINOLINE N-OXIDE price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N8141 4-Nitroquinoline N-oxide ≥98% 56-57-5 1g $136 2024-03-01 Buy
Sigma-Aldrich N8141 4-Nitroquinoline N-oxide ≥98% 56-57-5 5g $530 2024-03-01 Buy
TCI Chemical N0250 4-Nitroquinoline N-Oxide >98.0%(HPLC)(T) 56-57-5 1g $105 2024-03-01 Buy
TCI Chemical N0250 4-Nitroquinoline N-Oxide >98.0%(HPLC)(T) 56-57-5 5g $324 2024-03-01 Buy
Alfa Aesar L02605 4-Nitroquinoline N-oxide, 98+% 56-57-5 250mg $0 2021-12-16 Buy
Product number Packaging Price Buy
N8141 1g $136 Buy
N8141 5g $530 Buy
N0250 1g $105 Buy
N0250 5g $324 Buy
L02605 250mg $0 Buy

4-NITROQUINOLINE N-OXIDE Chemical Properties,Uses,Production

Chemical Properties

yellow-brown crystals or powder

Uses

4-Nitroquinoline N-oxide has been used as a model compound to study its carcinogenic effects.

Uses

4-Nitroquinoline N-Oxide is used in method for constructing animal model of oral mucosal malignancy related to Kras mutation.

Definition

ChEBI: A quinoline N-oxide carrying a nitro substituent at position 4.

General Description

Yellowish-brown plates or needles or yellow solid.

Air & Water Reactions

4-NITROQUINOLINE N-OXIDE is hygroscopic and light sensitive. Insoluble in water.

Reactivity Profile

4-NITROQUINOLINE N-OXIDE reacts with strong oxidizing agents.

Health Hazard

ACUTE/CHRONIC HAZARDS: 4-NITROQUINOLINE N-OXIDE may cause irritation. When heated to decomposition it may emit toxic fumes of carbon monoxide, carbon dioxide and nitrogen oxides.

Fire Hazard

Flash point data for 4-NITROQUINOLINE N-OXIDE are not available; however, 4-NITROQUINOLINE N-OXIDE is probably combustible.

Biochem/physiol Actions

Skin and lung tumor initiator under experimental conditions.

Safety Profile

Suspected carcinogen with experimental carcinogenic, neoplas tigenic, and tumorigenic data. Poison by intraperitoneal and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

The N-oxide recrystallises from aqueous acetone as yellow needles or platelets. [Ochiai J Org Chem 18 534 1953, Seki et al. J Phys Chem 91 126 1987, Beilstein 20 III/IV 3396.]

Global( 172)Suppliers
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ATK CHEMICAL COMPANY LIMITED
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career henan chemical co
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View Lastest Price from 4-NITROQUINOLINE N-OXIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Nitroquinoline 1-oxide pictures 2024-11-19 4-Nitroquinoline 1-oxide
56-57-5
US $40.00-30.00 / mg 99.87% 10g TargetMol Chemicals Inc.
4-NITROQUINOLINE N-OXIDE  pictures 2022-03-04 4-NITROQUINOLINE N-OXIDE
56-57-5
US $1.10 / g 1g 99.00% 100 Tons Dideu Industries Group Limited
4-NITROQUINOLINE N-OXIDE pictures 2021-10-14 4-NITROQUINOLINE N-OXIDE
56-57-5
US $10.00 / KG 1Kg/Bag 99% 20 tons Hebei Zhanyao Biotechnology Co. Ltd
TIMTEC-BB SBB006266 4-nitrochinolinn-oxid 4-nitrochinolinn-oxid(swedish) 4-nitro-quinolin1-oxide 4-nitroquinolineoxide 4-nqo nitrochin Quinoline, 4-nitro-, 1-oxide 4-NQNO Nitroquinolineoxide N-NITROQUINOLINE-N-OXIDE, 1000MG, NEAT NITROQUINOLINE-N-OXIDE NITROQUINOLINE-1-OXIDE 4-Nitroquinoline-N-oxide, HPLC 98% 4-NITROQUINOLINE N-OXIDE POWDER 4-NITROQUINOLINE N-OXIDE 98+% 4-NITRO-1-QUINOLINIUMOLATE 4-NITROQUINOLINE 1-OXIDE 4-NITROQUINOLINE N-OXIDE 4-NITROQUINOLINIUM-1-OLATE 4-NITROCHINOLINE-N-OXIDE N-(4-Nitrobenz 4-nitro-1-oxido-quinolin-1-ium 4-NitroquinolineN-Oxide> 4-Nitroquinoline-N-oxide, Comet assay grade 4-Nitroquinoline-1-oxide@100 μg/mL in Dichloromethane 4-NITROQUINOLINE N-OXIDE ISO 9001:2015 REACH NQNO NQO 4 Nitroquinoline 1 oxide,4Nitroquinoline 1oxide 4-Nitroquinoline N-Oxide, ≥ 98.0% 4-Nitroquinoline-N-oxide Solution in Methanol Cyclohexane Impurity 26 56-57-5 Building Blocks Heterocyclic Building Blocks Quinolines Nitroquinolines pharmacetical Nitroquinolines Quinolines