4-NITROQUINOLINE N-OXIDE
- CAS No.
- 56-57-5
- Chemical Name:
- 4-NITROQUINOLINE N-OXIDE
- Synonyms
- NQO;NQNO;4-nqo;4-NQNO;nitrochin;N-(4-Nitrobenz;Nitroquinolineoxide;TIMTEC-BB SBB006266;4-nitrochinolinn-oxid;4-nitroquinolineoxide
- CBNumber:
- CB1150485
- Molecular Formula:
- C9H6N2O3
- Molecular Weight:
- 190.16
- MDL Number:
- MFCD00006738
- MOL File:
- 56-57-5.mol
- MSDS File:
- SDS
Melting point | 154-156 °C(lit.) |
---|---|
Boiling point | 325.64°C (rough estimate) |
Density | 1.42 |
refractive index | 1.5570 (estimate) |
storage temp. | -20°C |
solubility | acetone: clear to hazy |
pka | -1.83±0.10(Predicted) |
form | Crystalline Solid |
color | yellow to brown |
BRN | 165756 |
Stability | Stable. Hygroscopic, light-sensitive. Incompatible with strong oxidizing agents. |
InChIKey | YHQDZJICGQWFHK-UHFFFAOYSA-N |
CAS DataBase Reference | 56-57-5(CAS DataBase Reference) |
EWG's Food Scores | 1 |
NCI Dictionary of Cancer Terms | 4-nitroquinoline 1-oxide; 4-NQO |
FDA UNII | X5081510EV |
EPA Substance Registry System | 4-Nitroquinoline 1-oxide (56-57-5) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS08 |
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Signal word | Danger | |||||||||
Hazard statements | H350 | |||||||||
Precautionary statements | P201-P308+P313 | |||||||||
Hazard Codes | T | |||||||||
Risk Statements | 45-68-40-20/21/22 | |||||||||
Safety Statements | 53-45-36/37-22 | |||||||||
RIDADR | 2811 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | VC2100000 | |||||||||
HazardClass | 6.1 | |||||||||
PackingGroup | II | |||||||||
HS Code | 29339900 | |||||||||
Toxicity | LD50 intraperitoneal in mouse: 190mg/kg | |||||||||
NFPA 704 |
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4-NITROQUINOLINE N-OXIDE price More Price(19)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | N8141 | 4-Nitroquinoline N-oxide ≥98% | 56-57-5 | 1g | $136 | 2024-03-01 | Buy |
Sigma-Aldrich | N8141 | 4-Nitroquinoline N-oxide ≥98% | 56-57-5 | 5g | $530 | 2024-03-01 | Buy |
TCI Chemical | N0250 | 4-Nitroquinoline N-Oxide >98.0%(HPLC)(T) | 56-57-5 | 1g | $105 | 2024-03-01 | Buy |
TCI Chemical | N0250 | 4-Nitroquinoline N-Oxide >98.0%(HPLC)(T) | 56-57-5 | 5g | $324 | 2024-03-01 | Buy |
Alfa Aesar | L02605 | 4-Nitroquinoline N-oxide, 98+% | 56-57-5 | 250mg | $0 | 2021-12-16 | Buy |
4-NITROQUINOLINE N-OXIDE Chemical Properties,Uses,Production
Chemical Properties
yellow-brown crystals or powder
Uses
4-Nitroquinoline N-oxide has been used as a model compound to study its carcinogenic effects.
Uses
4-Nitroquinoline N-Oxide is used in method for constructing animal model of oral mucosal malignancy related to Kras mutation.
Definition
ChEBI: A quinoline N-oxide carrying a nitro substituent at position 4.
General Description
Yellowish-brown plates or needles or yellow solid.
Air & Water Reactions
4-NITROQUINOLINE N-OXIDE is hygroscopic and light sensitive. Insoluble in water.
Reactivity Profile
4-NITROQUINOLINE N-OXIDE reacts with strong oxidizing agents.
Health Hazard
ACUTE/CHRONIC HAZARDS: 4-NITROQUINOLINE N-OXIDE may cause irritation. When heated to decomposition it may emit toxic fumes of carbon monoxide, carbon dioxide and nitrogen oxides.
Fire Hazard
Flash point data for 4-NITROQUINOLINE N-OXIDE are not available; however, 4-NITROQUINOLINE N-OXIDE is probably combustible.
Biochem/physiol Actions
Skin and lung tumor initiator under experimental conditions.
Safety Profile
Suspected carcinogen with experimental carcinogenic, neoplas tigenic, and tumorigenic data. Poison by intraperitoneal and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Purification Methods
The N-oxide recrystallises from aqueous acetone as yellow needles or platelets. [Ochiai J Org Chem 18 534 1953, Seki et al. J Phys Chem 91 126 1987, Beilstein 20 III/IV 3396.]
4-NITROQUINOLINE N-OXIDE Preparation Products And Raw materials
Raw materials
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Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29881 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
Hebei Zhanyao Biotechnology Co. Ltd | 15369953316 +8615369953316 | admin@zhanyaobio.com | China | 2123 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 22783 | 58 |
View Lastest Price from 4-NITROQUINOLINE N-OXIDE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-19 | 4-Nitroquinoline 1-oxide
56-57-5
|
US $40.00-30.00 / mg | 99.87% | 10g | TargetMol Chemicals Inc. | |||
2022-03-04 | 4-NITROQUINOLINE N-OXIDE
56-57-5
|
US $1.10 / g | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | ||
2021-10-14 | 4-NITROQUINOLINE N-OXIDE
56-57-5
|
US $10.00 / KG | 1Kg/Bag | 99% | 20 tons | Hebei Zhanyao Biotechnology Co. Ltd |
- 4-Nitroquinoline 1-oxide
56-57-5
- US $40.00-30.00 / mg
- 99.87%
- TargetMol Chemicals Inc.
- 4-NITROQUINOLINE N-OXIDE
56-57-5
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
- 4-NITROQUINOLINE N-OXIDE
56-57-5
- US $10.00 / KG
- 99%
- Hebei Zhanyao Biotechnology Co. Ltd
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