ChemicalBook >> CAS DataBase List >>2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one

2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one

2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one structure

CAS No.: 142217-81-0

Chemical Name:: 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one

Synonyms: DIBENZYLOXY GUANINE INTERMEDIATE;2-aMino-1,9-dihydro-9-[(1S,3R,4S)-2-Methylene-4-(benzyloxy)-3-[(benzyloxy)Methyl]cyclopentyl]-6H-Purin-6-one;ETA/ET1/N8;Entecavir-9;Entecavir E8;N-1 Entecavir API;Dibenzyl Entecavir;US-DMF No.: 026257;Entecavir Impurity 4;Entecavir dibenzylated

CBNumber:: CB11562443

Molecular Formula:: C26H27N5O3

Molecular Weight:: 457.52

MDL Number:: MFCD11977291

MOL File:: 142217-81-0.mol

Last updated:2024-04-26 17:21:34

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2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one Properties

Melting point	245-247°C (dec.)
Density	1.34
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMSO (Slightly)
form	Solid
pka	9?+-.0.20(Predicted)
color	White to Pale Beige
CAS DataBase Reference	142217-81-0(CAS DataBase Reference)
FDA UNII	IEC6P1L62X

SAFETY

Risk and Safety Statements

HS Code	29335990

2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one price More Price(15)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	D417550	3’,5’-Di-O-benzylEntecavir	142217-81-0	1g	$425	2021-12-16	Buy
TRC	D417550	3’,5’-Di-O-benzylEntecavir	142217-81-0	25mg	$155	2021-12-16	Buy
Matrix Scientific	093988	2-Amino-9-((1S,3R,4S)-4-(benzyloxy)-3-((benzyloxy)-methyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one 95+%	142217-81-0	1g	$1428	2021-12-16	Buy
AK Scientific	X6283	2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one	142217-81-0	1g	$523	2021-12-16	Buy
American Custom Chemicals Corporation	NUC0000801	(1S,3R,4S)-2-AMINO-9-[4-(BENZYLOXY)-3-(BENZYLOXYMETHYL)-2-METHYLIDENE-CYCLOPENTYL]-3H-PURIN-6-ONE 95.00%	142217-81-0	25MG	$525	2021-12-16	Buy

Product number	Packaging	Price	Buy
D417550	1g	$425	Buy
D417550	25mg	$155	Buy
093988	1g	$1428	Buy
X6283	1g	$523	Buy
NUC0000801	25MG	$525	Buy

2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one Chemical Properties,Uses,Production

Chemical Properties

White powder

Uses

3’,5’-Di-O-benzyl Entecavir is an intermediate in the preparation of the hepatitis B antiviral agent, Entecavir (E558900).

Uses

3’5’Di-O-benzyl Entecavir is an intermediate in the preparation of the hepatitis B antiviral agent, Entecavir (E558900).

2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one synthesis

Synthesis of 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one from Benzyl chloromethyl ether

2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one Preparation Products And Raw materials

Raw materials

Benzene, [(2,4-cyclopentadien-1-ylmethoxy)methyl]- (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(benzyloxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanone (1S,2R,3S,5R)-2-(Benzyloxymethyl)-6-oxabicyclo[3.1.0]hexan-3-ol SODIUM CYCLOPENTADIENIDE (1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane

6-(Benzyloxy)-9-((1S,3S)-4-(benzyloxy)-3-((benzyloxy)methyl)-2-methylenecyclopentyl)-N-((4-methoxyphenyl)diphenylmethyl)-9H-purin-2-amine (1S, 2R)-2-(Benzyloxymethyl)-1-hydroxy-3-cyclopentene (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol Benzyl chloromethyl ether

Triethyl orthoformate

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Preparation Products

2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one Suppliers

Global( 205)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20287	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	18779	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32957	60
Lianyungang happen teng technology co., LTD	15950718863	wang666xt@163.com	CHINA	295	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29884	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	sales@dolonchem.com	CHINA	2972	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2964	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8618959220845	sales@amoychem.com	China	6383	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58

Supplier	Advantage
Henan Fengda Chemical Co., Ltd	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Lianyungang happen teng technology co., LTD	58
career henan chemical co	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
Jinan Finer Chemical Co., Ltd	58
Xiamen AmoyChem Co., Ltd	58
Standardpharm Co. Ltd.	58

View Lastest Price from 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-21	2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one 142217-81-0	US $5.00 / kg	1kg	≥99%	200mt/year	Jinan Finer Chemical Co., Ltd
2024-04-27	2-amino-9-((1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one 142217-81-0	US $30.00-0.90 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2023-04-12	2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one 142217-81-0	US $1.00 / kg/bag	1kg/bag	99.45%	3000	Wuhan Dujiang Industrial Co., Ltd.

2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one
142217-81-0
US $5.00 / kg
≥99%
Jinan Finer Chemical Co., Ltd

2-amino-9-((1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one
142217-81-0
US $30.00-0.90 / KG
99%
Henan Fengda Chemical Co., Ltd

2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one
142217-81-0
US $1.00 / kg/bag
99.45%
Wuhan Dujiang Industrial Co., Ltd.

142217-81-0(2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one)Related Search:

EC 2.6.1.2 TERT-AMYL METHYL ETHER Methyl salicylate Kresoxim-methyl 4-Methoxybenzylchloride

Methyl acetate Tribenuron methyl Thiophanate-methyl Cyclopentyl methyl ether Acetaminophen

METSULFURON METHYL (1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane Methyl Entecavir hydrate 6-(Benzyloxy)-9-[(1S,3R,4S)-2-methylene-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopentyl]-9H-purine-2-amine

(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol 6-(Benzyloxy)-9-((1S,3S)-4-(benzyloxy)-3-((benzyloxy)methyl)-2-methylenecyclopentyl)-N-((4-methoxyphenyl)diphenylmethyl)-9H-purin-2-amine 2-AMino-1,9-dihydro-9-[(1S,3R,4S)-4-(hydroxydiMethylsilyl)-3-(hydroxyMethyl)-2-Methylenecyclopentyl]-6H-purin-6-one

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Entecavir InterMediate VIII IsoMer Entecavir InterMediate N-1 [1S-(1α,3α,4β)]-2-AMino-1,9-dihydro-9-[2-Methylene-4-(phenylMethoxy)-3-[(phenylMethoxy)Methyl]cyclopentyl]-6H 2-AMino-1,9-dihydro-9-[(1S,3R,4S)-2-Methylene-4-(phenylMethoxy)-3-[(phenylMethoxy)Methyl]cyclopentyl]-6H-purin-6-one 3',5'-Di-O-benzyl Entecavir 2-AMino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxyMethyl)-2-Methylenecyclopentyl]-6H-purin-6-one (interMediate 7) 2-AMino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxyMethyl)-2-Methylenecyclopentyl]-6H-purin 2-Amino-9-((1S,3R,4S)-4-(benzyloxy)-3-((benzyloxy)-methyl)-2-methylenecyclopentyl)-1H-purin-6(9H) 6H-Purin-6-one,2-amino-1,9-dihydro-9[(1S,3R,4S)-2-methylene-4-(phenylmethoxy)-3-[([phenylmethoxy)methyl]cyclopentyl]- N-1 Entecavir API 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-p Entecavir dibenzylated 2-Amino-9-((1S,3R,4S)-4-(benzyloxy)-3-((benzyloxy)-methyl)-2-methylenecyclopentyl)-1H-purin-6( (1S,3R,4S)-2-amino-9-[4-(benzyloxy)-3-(benzyloxymethyl)-2-methylidene-cyclopentyl]-3H-purin-6-one 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one Entecavir-9 2-amino-9-((1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one Entecavir E8 2-AMINO-9-((1S,3R,4S)-4-(BENZYLOXY)-3-(BENZYLOXYMETHYL)-2-METHYLENECYCLOPHENTYL)-1H-PURIN-6(9H)-ONE 2-aMino-9-((1S,3R,4S)-4-(benzyloxy)-3-(benzyloxyMethyl)-2-Methylenecyclopentyl)-9H-purin-6-ol 2-aMino-9-((1S,3R,4S)-4-(benzyloxy)-3-(benzyloxyMethyl)-2-Methylenecyclopentyl)-1H-[(13)C4]purin-6(9H)-one Entecavir Impurity 4 Dibenzyl Entecavir Dibenzyl Entecavir (3',5'-Di-O-Benzyl Entecavir) 2-amino-9-[(1S,3R,4S)-4-(benzyloxy)-3-[(benzyloxy)methyl]-2-methylidenecyclopentyl]-9H-purin-6-ol ETA/ET1/N8 Entecavir impurity SRR Entecavir Dibenzyl Impurity 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-Chemicalbook(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxy... US-DMF No.: 026257 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)- 2-methylenecyclopentyl]-6H- 2-aMino-1,9-dihydro-9-[(1S,3R,4S)-2-Methylene-4-(benzyloxy)-3-[(benzyloxy)Methyl]cyclopentyl]-6H-Purin-6-one DIBENZYLOXY GUANINE INTERMEDIATE 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4- (benzyloxy)-3- (benzyloxymethyl)-2-methylenecyclopentyl]}6H- purin-6-one(Ent-VIII) 2-Amino-1,9-dihydro-9- [(1S, 3R, 4S) -4-benzyloxy-3-benzyloxymethyl-2-methylenecyclopentyl] -6H-purine-6-one Dibenzyl Entecavir (3',5'-Di-O-Benzyl Entecavir) 3’,5’-Di-O-benzyl Entecavir 142217-81-0 142271-81-0 142214-77-4