N-Acetyl-L-phenylalanine
- CAS No.
- 2018-61-3
- Chemical Name:
- N-Acetyl-L-phenylalanine
- Synonyms
- AC-PHE-OH;Ac-L-Phe-OH;Acetylphenylalanine;L-Phenylalanine, N-acetyl-;N-Ac-L-Phe-OH;Ac-L-Phe;NSC 45699;ACETYL-L-PHENYLALANINE;(2S)-2-Acetamido-3-phenylpropanoic acid;H-Ac-Phe-OH
- CBNumber:
- CB1170986
- Molecular Formula:
- C11H13NO3
- Molecular Weight:
- 207.23
- MDL Number:
- MFCD00063158
- MOL File:
- 2018-61-3.mol
- MSDS File:
- SDS
Melting point | 171-173 °C(lit.) |
---|---|
alpha | 40 º (c=1,methanol) |
Boiling point | 346.25°C (rough estimate) |
Density | 1.1878 (rough estimate) |
refractive index | 40 ° (C=5, MeOH) |
storage temp. | Sealed in dry,Room Temperature |
solubility | Solubility in methanol (almost transparency). Soluble in acetone and ethanol (20 mg/ ml). |
form | Fine Crystalline Powder or Needles |
pka | 3.56±0.10(Predicted) |
color | White to off-white |
optical activity | [α]22/D +40.0°, c = 1 in methanol |
InChIKey | CBQJSKKFNMDLON-JTQLQIEISA-N |
CAS DataBase Reference | 2018-61-3(CAS DataBase Reference) |
FDA UNII | NP5BT39467 |
NIST Chemistry Reference | L-phenylalanine, n-acetyl-(2018-61-3) |
EPA Substance Registry System | L-Phenylalanine, N-acetyl- (2018-61-3) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H335 | |||||||||
Precautionary statements | P261-P305+P351+P338 | |||||||||
Safety Statements | 24/25 | |||||||||
WGK Germany | 3 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29242990 | |||||||||
NFPA 704 |
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N-Acetyl-L-phenylalanine price More Price(35)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 857459 | N-Acetyl-L-phenylalanine ReagentPlus , 99% | 2018-61-3 | 1g | $15 | 2024-03-01 | Buy |
Sigma-Aldrich | 857459 | N-Acetyl-L-phenylalanine ReagentPlus , 99% | 2018-61-3 | 5g | $78.4 | 2024-03-01 | Buy |
TCI Chemical | A1541 | N-Acetyl-L-phenylalanine >99.0%(T) | 2018-61-3 | 5g | $18 | 2024-03-01 | Buy |
TCI Chemical | A1541 | N-Acetyl-L-phenylalanine >99.0%(T) | 2018-61-3 | 25g | $51 | 2024-03-01 | Buy |
Alfa Aesar | B23812 | N-Acetyl-L-phenylalanine, 99% | 2018-61-3 | 1g | $30.65 | 2024-03-01 | Buy |
N-Acetyl-L-phenylalanine Chemical Properties,Uses,Production
Chemical Properties
white to off-white fine cryst. powder or needles
Uses
N-Acetyl-L-phenylalanine is an protected analogue of L-Phenylalanine (P319415), an essential amino acid produced for medical, feed, and nutritional applications such as in the preparation of Aspartame.
Uses
It is an essential amino acid produced for medical, feed, and nutritional applications such as in the preparation of aspartame. It is applied as an antidepressant.
Definition
ChEBI: The N-acetyl derivative of L-phenylalanine.
General Description
N-Acetyl-L-phenylalanine is an acetyl analog of L-phenylalanine. It is widely used as a reactant to synthesize methyl or ethyl esters of N-acetyl-L-phenylalanine, which are employed as versatile building blocks in peptide synthesis.
Purification Methods
N-Acetyl-L-phenylalanine is recrystallised from H2O, 20% MeOH/H2O, or CHCl3; dry and store it at 4o. The (DL)-isomer crystallises from H2O, Me2CO, EtOAc, or CHCl3 with m 152-154o and the solubilities in w% at 25o are 0.73 (H2O), 4.3 (Me2CO), 0.79 (EtOAc) and 0.34 (CHCl3) [Kerr & Niemann J Org Chem 23 893 1958, Overby & Ingersoll J Am Chem Soc 73 3363 1951, L: Fu et al. J Am Chem Soc 76 6057 1954, Bender & Glasson J Am Chem Soc 81 1591 1959]. [Beilstein 14 I 238, 4 IV 1575.]
![52386-78-4](/CAS/20200611/GIF/52386-78-4.gif)
![2018-61-3](/CAS/GIF/2018-61-3.gif)
N-Acetyl-L-phenylalanine Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +8615383190639 | admin@86-ss.com | China | 1000 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 16914 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21668 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29892 | 58 |
NINGBO INNO PHARMCHEM CO., LTD. | 13867897135 | sales@nbinno.com | CHINA | 925 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2967 | 58 |
Huaian yishu technology co.,ltd | 86-0517-85883738 13852390259 | sales@yishuchem.com | CHINA | 53 | 58 |
View Lastest Price from N-Acetyl-L-phenylalanine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2024-08-27 | N-Acetyl-L-phenylalanine
2018-61-3
|
US $0.00 / Kg/Drum | 1KG | 98%min | 500kgs | WUHAN FORTUNA CHEMICAL CO., LTD | |
![]() |
2024-08-27 | N-Acetyl-L-phenylalanine
2018-61-3
|
US $100.00-75.00 / kg | 1kg | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | |
![]() |
2021-08-12 | N-Acetyl-L-phenylalanine
2018-61-3
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- N-Acetyl-L-phenylalanine
2018-61-3
- US $0.00 / Kg/Drum
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- N-Acetyl-L-phenylalanine
2018-61-3
- US $100.00-75.00 / kg
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
-
- N-Acetyl-L-phenylalanine
2018-61-3
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd