Ethyl nitroacetate
- CAS No.
- 626-35-7
- Chemical Name:
- Ethyl nitroacetate
- Synonyms
- NSC 42302;JACS-626-35-7;Ethlnitroacetate;2-nitrobutanoate;Ethyl nitrocetate;ETHYL NITROACETATE;NITRO ETHYL ACETATE;EthylNitroacetate>Ethylnitroacetate,97%;Ethyl nitroacetate,98%
- CBNumber:
- CB1175310
- Molecular Formula:
- C4H7NO4
- Molecular Weight:
- 133.1
- MDL Number:
- MFCD00007403
- MOL File:
- 626-35-7.mol
- MSDS File:
- SDS
| Boiling point | 105-107 °C/25 mmHg (lit.) |
|---|---|
| Density | 1.199 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 198 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| pka | pK1:5.85 (25°C) |
| form | Liquid |
| color | Clear colorless to slightly yellow |
| Water Solubility | Slightly soluble in water. Soluble in chloroform and ethyl acetate. |
| BRN | 1210027 |
| InChIKey | FTKASJMIPSSXBP-UHFFFAOYSA-N |
| CAS DataBase Reference | 626-35-7(CAS DataBase Reference) |
| FDA UNII | 7SX8B7W4RD |
| NIST Chemistry Reference | Acetic acid, nitro-, ethyl ester(626-35-7) |
| EPA Substance Registry System | Acetic acid, nitro-, ethyl ester (626-35-7) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H227-H315-H319 | |||||||||
| Precautionary statements | P280g-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 38 | |||||||||
| Safety Statements | 23-24/25-37 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | AJ1074000 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | T | |||||||||
| HazardClass | IRRITANT, KEEP COLD | |||||||||
| HS Code | 29159080 | |||||||||
| NFPA 704 |
|
Ethyl nitroacetate price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 192333 | Ethyl nitroacetate 97% | 626-35-7 | 5g | $43.1 | 2024-03-01 | Buy |
| Sigma-Aldrich | 192333 | Ethyl nitroacetate 97% | 626-35-7 | 25g | $166 | 2024-03-01 | Buy |
| TCI Chemical | N0657 | Ethyl Nitroacetate >95.0%(GC) | 626-35-7 | 5g | $56 | 2024-03-01 | Buy |
| TCI Chemical | N0657 | Ethyl Nitroacetate >95.0%(GC) | 626-35-7 | 25g | $164 | 2024-03-01 | Buy |
| Alfa Aesar | A14433 | Ethyl nitroacetate, 97% | 626-35-7 | 5g | $63.65 | 2024-03-01 | Buy |
Ethyl nitroacetate Chemical Properties,Uses,Production
Chemical Properties
clear colourless to slightly yellow liquid
Uses
Ethyl Nitroacetate is an ester of nitrocarboxylic acid used as an intermediate in the preparation of unsubstituted amino acids.
Uses
Ethyl nitroacetate has been used in the synthesis of γ-oxoacids via Michael addition reaction with α,β-unsaturated ketones, fuctionalization of C4-position on pyrimidine and C6-position on 2?-deoxyguanosine to produce novel nucleosides, facile synthesis of α,α-diisobutylglycine, synthesis of DL-4,4-difluoroglutamic acid. It is also used as an intermediate in the preparation of unsubstituted amino acids.
Synthesis Reference(s)
The Journal of Organic Chemistry, 59, p. 1208, 1994 DOI: 10.1021/jo00084a047
Purification Methods
Purify the ester by repeated distillation. IR:max 1748 (CO2), 1570 and 1337 (NO2), and 800cm-1 [Haszeldine J Chem Soc 2525 1953]. The hydrazine salt crystallises from 95% EtOH or MeOH as yellow crystals m 104-105o [Ungnade & Kissinger J Org Chem 22 1661 1957, Emmons & Freeman J Am Chem Soc 77 4391 1955]. [Beilstein 2 IV 537.]
Ethyl nitroacetate Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531157085 | abby@chuanghaibio.com | China | 8808 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12809 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29730 | 60 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Zjartschem | +86-571 87238903 | jocelynpan@zjarts.com | CHINA | 988 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29858 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10406 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
View Lastest Price from Ethyl nitroacetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-23 | Ethyl nitroacetate
626-35-7
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-04-21 | Ethyl nitroacetate
626-35-7
|
US $0.00-0.00 / kg | 1kg | 98 | 1000 | Wuhan Circle Star Chem-medical Technology Co.,Ltd | |
 |
2025-03-21 | Ethyl nitroacetate
626-35-7
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mujin Biotechnology Co.,Ltd |
-
- Ethyl nitroacetate
626-35-7
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Ethyl nitroacetate
626-35-7
- US $0.00-0.00 / kg
- 98
- Wuhan Circle Star Chem-medical Technology Co.,Ltd
-
- Ethyl nitroacetate
626-35-7
- US $0.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd