Ethyl nitroacetate
- CAS No.
- 626-35-7
- Chemical Name:
- Ethyl nitroacetate
- Synonyms
- NSC 42302;JACS-626-35-7;Ethlnitroacetate;2-nitrobutanoate;Ethyl nitrocetate;ETHYL NITROACETATE;NITRO ETHYL ACETATE;EthylNitroacetate>Ethylnitroacetate,97%;Ethyl nitroacetate,98%
- CBNumber:
- CB1175310
- Molecular Formula:
- C4H7NO4
- Molecular Weight:
- 133.1
- MDL Number:
- MFCD00007403
- MOL File:
- 626-35-7.mol
- MSDS File:
- SDS
Boiling point | 105-107 °C/25 mmHg (lit.) |
---|---|
Density | 1.199 g/mL at 25 °C (lit.) |
refractive index |
n |
Flash point | 198 °F |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
form | Liquid |
pka | pK1:5.85 (25°C) |
color | Clear colorless to slightly yellow |
Water Solubility | Slightly soluble in water. Soluble in chloroform and ethyl acetate. |
BRN | 1210027 |
InChIKey | FTKASJMIPSSXBP-UHFFFAOYSA-N |
CAS DataBase Reference | 626-35-7(CAS DataBase Reference) |
FDA UNII | 7SX8B7W4RD |
NIST Chemistry Reference | Acetic acid, nitro-, ethyl ester(626-35-7) |
EPA Substance Registry System | Acetic acid, nitro-, ethyl ester (626-35-7) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H227-H315-H319 | |||||||||
Precautionary statements | P280g-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 38 | |||||||||
Safety Statements | 23-24/25-37 | |||||||||
WGK Germany | 2 | |||||||||
RTECS | AJ1074000 | |||||||||
Hazard Note | Irritant | |||||||||
TSCA | T | |||||||||
HazardClass | IRRITANT, KEEP COLD | |||||||||
HS Code | 29159080 | |||||||||
NFPA 704 |
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Ethyl nitroacetate price More Price(37)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 192333 | Ethyl nitroacetate 97% | 626-35-7 | 5g | $43.1 | 2024-03-01 | Buy |
Sigma-Aldrich | 192333 | Ethyl nitroacetate 97% | 626-35-7 | 25g | $166 | 2024-03-01 | Buy |
TCI Chemical | N0657 | Ethyl Nitroacetate >95.0%(GC) | 626-35-7 | 5g | $56 | 2024-03-01 | Buy |
TCI Chemical | N0657 | Ethyl Nitroacetate >95.0%(GC) | 626-35-7 | 25g | $164 | 2024-03-01 | Buy |
Alfa Aesar | A14433 | Ethyl nitroacetate, 97% | 626-35-7 | 5g | $63.65 | 2024-03-01 | Buy |
Ethyl nitroacetate Chemical Properties,Uses,Production
Chemical Properties
clear colourless to slightly yellow liquid
Uses
Ethyl Nitroacetate is an ester of nitrocarboxylic acid used as an intermediate in the preparation of unsubstituted amino acids.
Uses
Ethyl nitroacetate has been used in the synthesis of γ-oxoacids via Michael addition reaction with α,β-unsaturated ketones, fuctionalization of C4-position on pyrimidine and C6-position on 2?-deoxyguanosine to produce novel nucleosides, facile synthesis of α,α-diisobutylglycine, synthesis of DL-4,4-difluoroglutamic acid. It is also used as an intermediate in the preparation of unsubstituted amino acids.
Synthesis Reference(s)
The Journal of Organic Chemistry, 59, p. 1208, 1994 DOI: 10.1021/jo00084a047
Purification Methods
Purify the ester by repeated distillation. IR:max 1748 (CO2), 1570 and 1337 (NO2), and 800cm-1 [Haszeldine J Chem Soc 2525 1953]. The hydrazine salt crystallises from 95% EtOH or MeOH as yellow crystals m 104-105o [Ungnade & Kissinger J Org Chem 22 1661 1957, Emmons & Freeman J Am Chem Soc 77 4391 1955]. [Beilstein 2 IV 537.]
Ethyl nitroacetate Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12460 | 58 |
Hebei Duling International Trade Co. LTD | +8617333973358 | sales01@hbduling.cn | China | 15437 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
Zjartschem | +86-571-8723 8903 jocelynpan@zjarts.com | jocelynpan@zjarts.com | CHINA | 993 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29897 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10260 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8827 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
View Lastest Price from Ethyl nitroacetate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-06-16 | Ethyl nitroacetate
626-35-7
|
US $67.00 / kg | 1kg | 99% | 5000 tons | Hebei Duling International Trade Co. LTD | ||
2023-09-06 | Ethyl nitroacetate
626-35-7
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | ||
2022-02-22 | Ethyl nitroacetate
626-35-7
|
US $0.00 / KG | 1KG | 99.1% | 100 tons | Honest Joy Holdings Limited
|
- Ethyl nitroacetate
626-35-7
- US $67.00 / kg
- 99%
- Hebei Duling International Trade Co. LTD
- Ethyl nitroacetate
626-35-7
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
- Ethyl nitroacetate
626-35-7
- US $0.00 / KG
- 99.1%
- Honest Joy Holdings Limited