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CYCLO (ARG-GLY-ASP-D-PHE-LYS)

CYCLO (ARG-GLY-ASP-D-PHE-LYS) structure

CAS No.: 161552-03-0

Chemical Name:: CYCLO (ARG-GLY-ASP-D-PHE-LYS)

Synonyms: CYCLO;c(RGDfK);CYCLO(-RGDFK);Cyclo(RGDfK) peptide;RGDFK;cyclo(RGD-DPhe-K);Cyclo (-RGDfK) TFA;Cyclo(-RGDfK), >98%;Cyclic RGDFK peptide;ARG-GLY-ASP-D-PHE-LYS

CBNumber:: CB1186608

Molecular Formula:: C27H41N9O7

Molecular Weight:: 603.67

MDL Number:: MFCD00937400

MOL File:: Mol file

Last updated:2024-11-17 16:00:36

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CYCLO (ARG-GLY-ASP-D-PHE-LYS) Properties

Melting point	191℃ (decomposition)
Density	1.47±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	≥30.19 mg/mL in DMSO; insoluble in EtOH; ≥59.2 mg/mL in H2O
form	Powder
pka	4.01±0.10(Predicted)
color	White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

CYCLO (ARG-GLY-ASP-D-PHE-LYS) price More Price(66)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	29514	Cyclo(RGDfK)	161552-03-0	5mg	$121	2024-03-01	Buy
Cayman Chemical	29514	Cyclo(RGDfK)	161552-03-0	100mg	$1082	2024-03-01	Buy
Cayman Chemical	29514	Cyclo(RGDfK)	161552-03-0	10mg	$230	2024-03-01	Buy
Cayman Chemical	29514	Cyclo(RGDfK)	161552-03-0	25mg	$481	2024-03-01	Buy
Usbiological	236998	Cyclo	161552-03-0	100mg	$219	2021-12-16	Buy

Product number	Packaging	Price	Buy
29514	5mg	$121	Buy
29514	100mg	$1082	Buy
29514	10mg	$230	Buy
29514	25mg	$481	Buy
236998	100mg	$219	Buy

CYCLO (ARG-GLY-ASP-D-PHE-LYS) Chemical Properties,Uses,Production

Uses

Cyclo (-RGDfK) Trifluoroacetic Acid Salt is a potent inhibitor of αvβ3 integrin. Used in tumor therapy due to the targeting of the VEGFR2 gene by sRNA.

Biological Activity

in one study where this peptide was labeled with 125i, it was found to bind specifically and with high affinity to αvβ3 receptors on neovascular blood vessel sections of different major human cancers. the integrin alpha(iib)beta(3)-specific cyclic hexapeptide contains an arg-gly-asp (rgd) sequence.

target

Integrin

CYCLO (ARG-GLY-ASP-D-PHE-LYS) synthesis

Synthesis of CYCLO (ARG-GLY-ASP-D-PHE-LYS) from Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

CYCLO (ARG-GLY-ASP-D-PHE-LYS) Preparation Products And Raw materials

Raw materials

Fmoc-Lys(Trt)-OH Fmoc-N'-Acetyl-L-lysine Fmoc-Asp(OtBu)-OH

Preparation Products

CYCLO (ARG-GLY-ASP-D-PHE-LYS) Suppliers

Global( 143)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Adachibio Inc.	+8108027837258	sales@adachi-bio.com	China	992	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
GenicBio Limited	+86-21-37621270	service@genicbio.com	CHINA	991	58
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	965	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10406	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Shanghai Longyu Biotechnology Co., Ltd.	+8619521488211	info@longyupharma.com	China	2555	58
Hebei Yanxi Chemical Co., Ltd.	+8617531153977	allison@yan-xi.com	China	5854	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32159	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10244	58

Supplier	Advantage
Adachibio Inc.	58
ATK CHEMICAL COMPANY LIMITED	60
GenicBio Limited	58
Biochempartner	58
Shenzhen Nexconn Pharmatechs Ltd	58
BOC Sciences	58
Shanghai Longyu Biotechnology Co., Ltd.	58
Hebei Yanxi Chemical Co., Ltd.	58
TargetMol Chemicals Inc.	58
Hubei Ipure Biology Co., Ltd	58

View Lastest Price from CYCLO (ARG-GLY-ASP-D-PHE-LYS) manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-04-04	CYCLO (ARG-GLY-ASP-D-PHE-LYS) 161552-03-0	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2024-11-17	Cyclo(-RGDfK) 161552-03-0	US $40.00-177.00 / mg		99.83%	10g	TargetMol Chemicals Inc.
2021-08-18	CYCLO (ARG-GLY-ASP-D-PHE-LYS) USP/EP/BP 161552-03-0	US $1.10 / g	1g	99.9%	100 Tons min	Dideu Industries Group Limited

CYCLO (ARG-GLY-ASP-D-PHE-LYS)
161552-03-0
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

Cyclo(-RGDfK)
161552-03-0
US $40.00-177.00 / mg
99.83%
TargetMol Chemicals Inc.

CYCLO (ARG-GLY-ASP-D-PHE-LYS) USP/EP/BP
161552-03-0
US $1.10 / g
99.9%
Dideu Industries Group Limited

CYCLO (ARG-GLY-ASP-D-PHE-LYS) Spectrum

CYCLO (ARG-GLY-ASP-D-PHE-LYS)(161552-03-0)MS

CYCLO (ARG-GLY-ASP-D-PHE-LYS) cyclo (Arg-Gly-Asp-Phe-Lys) Cyclic RGDFK peptide Cyclo(L-arginylglycyl-L-alpha-aspartyl-D-phenylalanyl-L-lysyl) Cyclo(-Arg-Gly-Asp-D-Phe-Lys) Trifluoroacetate salt Cyclo (-RGDfK) TFA CYCLO(RGDFK) PEPTIDE;CYCLIC RGDFK PEPTIDE Cyclo(-RGDfK)(free base) C(RGDFK);CYCLO (RGDFK) Cyclo(-RGDfK), >98% Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-lysyl) CYCLO (ARG-GLY-ASP-D-PHE-LYS) USP/EP/BP CYCLO(-RGDFK) c(RGDfK) Cyclo(RGDfK) peptide CYCLO cyclo(RGD-DPhe-K) Cyclo(-RGDfK),inhibit,Microvasculature,cancer,Integrin,tumoral cell,αvβ3 integrin,Cyclo(RGDfK),ligand,Inhibitor,Cyclo( RGDfK) ARG-GLY-ASP-D-PHE-LYS RGDFK 2-((2S,5R,8S,11S)-8-(4-Aminobutyl)-5-benzyl-11-(3-guanidinopropyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)acetic acid Cyclo(-RGDfK), 10 mM in DMSO Cyclo (-RGDfK) - 1 mg 161552-03-0 C27H41N9O7 peptide RGD