Anti-A4 Amyloid protein, Anti-ABETA, Anti-ABPP, Anti-AD1, Anti-Amyloid β A4 protein, Anti-Amyloid-β protein (ABP), Anti-APPI
- CAS No.
- Chemical Name:
- Anti-A4 Amyloid protein, Anti-ABETA, Anti-ABPP, Anti-AD1, Anti-Amyloid β A4 protein, Anti-Amyloid-β protein (ABP), Anti-APPI
- Synonyms
- Anti-β-Amyloid (22-35) antibody produced in rabbit;Anti-A4 Amyloid protein, Anti-ABETA, Anti-ABPP, Anti-AD1, Anti-Amyloid β A4 protein, Anti-Amyloid-β protein (ABP), Anti-APPI
- CBNumber:
- CB12096031
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Anti-A4 Amyloid protein, Anti-ABETA, Anti-ABPP, Anti-AD1, Anti-Amyloid β A4 protein, Anti-Amyloid-β protein (ABP), Anti-APPI price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A3356 | Anti-β-Amyloid (22-35) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution | 25μL | $159 | 2024-03-01 | Buy | |
| Sigma-Aldrich | A3356 | Anti-β-Amyloid (22-35) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution | 200μL | $371.4 | 2024-03-01 | Buy |
Anti-A4 Amyloid protein, Anti-ABETA, Anti-ABPP, Anti-AD1, Anti-Amyloid β A4 protein, Anti-Amyloid-β protein (ABP), Anti-APPI Chemical Properties,Uses,Production
Uses
Rabbit anti-β-amyloid (22-35) antibody can be used for ELISA at a concentration of 0.2-0.4μg/mL using β-amyloid peptide (22-35). The product can also be used for western blot at 0.25-0.5μg/mL using β-amyloid peptide (1-40).
General Description
Rabbit anti-β-amyloid (22-35) antibody specifically recognizes β-amyloid (22-35), β-amyloid (25-35), β-amyloid (1-40) and β-amyloid (1-42) and does not react with β-amyloid (32-35) and β-amyloid (35-25) by ELISA. The antibody detects β-amyloid (1-40) by immunoblotting (approx. 4kDa). Staining of the β-amyloid (1-40) band in immunoblotting is specifically inhibited by the immunizing peptide.
Biochem/physiol Actions
Secreted Aβ lead to synaptic and neuritic compromise and glial activation. Aggregates of amyloid β peptide are found deposited in the brains of Alzheimer′s patients. Aβ(25-35) and Aβ(22-35) fragments are highly toxic segments of β-amyloid peptides that promote inflammatory processes in astrocytes and fibrillary aggregation of Aβ, thus representing a promising therapeutic target for Alzheimer′s.