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ChemicalBook >> CAS DataBase List >>[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one

[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one

[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one Structure
[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one structure
CAS No.
546-78-1
Chemical Name:
[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one
Synonyms
Thujenone;Thujen-2-one;(-)-Umbellulone;(1R,5S)-(-)-3-Thujen-2-one;(-)-Umbellulone >=98% (HPLC);(1R, 5S)-4-Methyl-1-propan-2-ylbicyclo(3.1.0)hex-3-en-2-one;[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one
CBNumber:
CB12235115
Molecular Formula:
Molecular Weight:
0
MDL Number:
MFCD26961114
MOL File:
546-78-1.mol
MSDS File:
SDS
Last updated:2025-01-21 19:06:49
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[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one Properties

storage temp. -20°C
solubility DMSO : 250 mg/mL (1664.23 mM; Need ultrasonic)
form Oil
color colorless to light brown
biological source Umbellularia californica Nutt.

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Hazard Codes  Xn
Risk Statements  22-43
Safety Statements  36/37

[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0782 (-)-Umbellulone ≥98% (HPLC) 546-78-1 5mg $82.9 2024-03-01 Buy
Adipogen Life Sciences AG-CN2-0085-M010 Umbellulone ≥98%(HPLC) 546-78-1 10mg $140 2021-12-16 Buy
American Custom Chemicals Corporation API0045882 (-)-UMBELLULONE 95.00% 546-78-1 5MG $517.66 2021-12-16 Buy
Product number Packaging Price Buy
SML0782 5mg $82.9 Buy
AG-CN2-0085-M010 10mg $140 Buy
API0045882 5MG $517.66 Buy

[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one Chemical Properties,Uses,Production

Definition

ChEBI: Umbellulone is a ketone.

Biochem/physiol Actions

(-)-Umbellulone, isolated from the"headache tree" Umbellularia californica Nutt, is a selective activator of Transient Receptor Potential Anykrin 1 (TRPA1) channels. (-)-Umbellulone activates TRPA1 channels on nociceptive trigeminal afferents, resulting in release of CGRP and CGRP-mediated neurogenic vasodilatation, causing a painful cold sensation and headache/migraine.

[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

Dihydroumbellulone

[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one Suppliers

Global( 14)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51456 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9409 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44918 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29774 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 5018 58
Baoji Didu Pharmaceutical and Chemical Co., Ltd 02961856358 15829046862 1035@dideu.com China 10011 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9266 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19699 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Sigma-Aldrich 80
Shanghai EFE Biological Technology Co., Ltd. 58
DC Chemicals 58
Energy Chemical 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
Nantong QuanYi Biotechnology Co., Ltd 58
Baoji Didu Pharmaceutical and Chemical Co., Ltd 58
RD International Technology Co., Limited 58
TargetMol Chemicals Inc. 58
[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one (1R, 5S)-4-Methyl-1-propan-2-ylbicyclo(3.1.0)hex-3-en-2-one (1R,5S)-(-)-3-Thujen-2-one Thujen-2-one Thujenone (-)-Umbellulone (-)-Umbellulone >=98% (HPLC) 546-78-1