1-(P-METHOXYPHENYL)-1-BUTEN-3-ONE
- CAS No.
- 943-88-4
- Chemical Name:
- 1-(P-METHOXYPHENYL)-1-BUTEN-3-ONE
- Synonyms
- NSC31752;AI3-00222;NSC-31752;NSC 31752;ANISALACETONE;Dobutamine 25;p-Anisalacetone;anisylideneacetone;Ani-sylideneacetone;p-Anisilidenacetone
- CBNumber:
- CB1245673
- Molecular Formula:
- C11H12O2
- Molecular Weight:
- 176.21
- MDL Number:
- MFCD00017251
- MOL File:
- 943-88-4.mol
Melting point | 75-77° |
---|---|
Boiling point | 267.83°C (rough estimate) |
Density | 1.0558 (rough estimate) |
refractive index | 1.5100 (estimate) |
storage temp. | Sealed in dry,Room Temperature |
solubility | Chloroform (Slightly), Methanol (Very Slightly) |
form | Solid |
color | White or yellowish leafy crystals. |
LogP | 2.25 |
EWG's Food Scores | 1-3 |
FDA UNII | 79U9LYF10I |
EPA Substance Registry System | 3-Buten-2-one, 4-(4-methoxyphenyl)- (943-88-4) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
HazardClass | IRRITANT |
HS Code | 2914500090 |
Toxicity | Both the acute oral LD50 value in rats and the acute dermal LD50 value in rabbits exceeded 5 g/kg (Wohl, 1974). |
1-(P-METHOXYPHENYL)-1-BUTEN-3-ONE price More Price(16)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | M226670 | 4-(4-Methoxyphenyl)-3-buten-2-one | 943-88-4 | 5g | $720 | 2021-12-16 | Buy |
Apolloscientific | OR26402 | 4-(4-Methoxyphenyl)but-3-en-2-one | 943-88-4 | 5g | $492 | 2021-12-16 | Buy |
Matrix Scientific | 043222 | 4-(4-Methoxyphenyl)-3-buten-2-one >95% | 943-88-4 | 5g | $285 | 2021-12-16 | Buy |
SynQuest Laboratories | 2917-1-44 | 4-(4-Methoxyphenyl)but-3-en-2-one | 943-88-4 | 5G | $365 | 2021-12-16 | Buy |
Matrix Scientific | 043222 | 4-(4-Methoxyphenyl)-3-buten-2-one >95% | 943-88-4 | 500mg | $53 | 2021-12-16 | Buy |
1-(P-METHOXYPHENYL)-1-BUTEN-3-ONE Chemical Properties,Uses,Production
Aroma
Slightly pungent, but in dilution sweet, floral and creamy odor of considerable tenacity.
1-(P-METHOXYPHENYL)-1-BUTEN-3-ONE, like many related ketones, has met with much resistance from perfumers and dermatologists. However, it has survived all attacks under the usual and probably reasonable argument, that in normal concentrations, it will have no harmful effects on the human
skin. Undoubtedly, perfumers are using scores
of materials with a much shorter history of
successful application.
It finds use in many floral perfume compositions, mainly Cassie bases, Acacia, Lilac,
Sweet Pea, Hyacinth, etc. In even lower concentration, it may give interesting effects in
Lavender, Fougeres, New Mown Hay (for which it was originally intended), etc.
Occurrence
Has apparently not been reported to occur in nature.
Uses
4-(4-methoxyphenyl)-3-buten-2-one is used in preparation of Thiazole derivatives as protein secretion inhibitors.
Preparation
From anisaldehyde and acetone by condensation using a suitable catalyst.
Metabolism
When the side chain of a mixed ketone contains a double bond, both the keto group and the double bond are potentially reducible in vivo. In a related material, methyl styryl ketone ( C6 H5 CH:CHCOCH3 ) , the keto group appears to be more readily reduced than the double bond,with reduction via C6 H5 CH:CH.CH(OH)CH3to the completely reduced carbinol compoundC6 H5[CH2]2CH(OH) CH3, which is found as the main product (Fischer & Bielig, 1940). The ether link is relatively stable in substituted anisoles, such as anethole (p-CH3OC 6H4CH:CH CH4), containinga potential carboxyl group attached to the aromatic ring (Williams, 1959).
1-(P-METHOXYPHENYL)-1-BUTEN-3-ONE Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3883 | 58 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29858 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
ShenZhen H&D Pharmaceutical Technology Co., LTD | +8618627948422 | sale@hdimpurity.com | China | 3619 | 58 |
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD. | +8618950047208 | ellena@amitychem.com | China | 43416 | 58 |
View Lastest Price from 1-(P-METHOXYPHENYL)-1-BUTEN-3-ONE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2025-03-04 | Dobutamine Impurity 25
943-88-4
|
US $0.00 / mg | 10mg | 0.98 | 10g | ShenZhen H&D Pharmaceutical Technology Co., LTD | |
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2024-08-29 | 1-(P-METHOXYPHENYL)-1-BUTEN-3-ONE
943-88-4
|
US $0.10 / KG | 1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- Dobutamine Impurity 25
943-88-4
- US $0.00 / mg
- 0.98
- ShenZhen H&D Pharmaceutical Technology Co., LTD
-
- 1-(P-METHOXYPHENYL)-1-BUTEN-3-ONE
943-88-4
- US $0.10 / KG
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
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