ChemicalBook >> CAS DataBase List >>1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone

1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone

1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone structure

CAS No.: 1125812-58-9

Chemical Name:: 1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone

Synonyms: 1-(3-chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethan-1-one;afoxolaner-002;afoxolaner Impurity 6;1-[3-Chloro-5-trifluoromethylphenyl;2,2,2-trifluoro-3'-chloro-5'-trifluoromethylacetophenone;3'-Chloro-5'-trifluoroMethyl-2,2,2-trifluoroacetophenone;3'-Chloro-5'-trifluoromethoxy-2,2,2-trifluoroacetophenone;3'-Chloro-5'-trifluoromethoxy-2,2,2-trifluoroacetophenone;1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone;Ethanone, 1-[3-chloro-5-(trifluoromethyl)phenyl]-2,2,2-trifluoro-

CBNumber:: CB12514588

Molecular Formula:: C9H3ClF6O

Molecular Weight:: 276.56

MDL Number:: MFCD19440960

MOL File:: 1125812-58-9.mol

MSDS File:: SDS

Last updated:2023-06-09 13:57:52

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1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone Properties

Boiling point	203℃
Density	1.512
Flash point	77℃
storage temp.	2-8°C

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS05
Signal word	Danger
Hazard statements	H302-H314
Precautionary statements	P260-P264-P280-P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P305+P351+P338-P405-P501-P264-P270-P301+P312-P330-P501

1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone price More Price(9)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Activate Scientific	AS146793	1-(3-Chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethanone 95%	1125812-58-9	1g	$120	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0361882	1-(3-CHLORO-5-(TRIFLUOROMETHYL)PHENYL)-2,2,2-TRIFLUOROETHANONE 95.00%	1125812-58-9	0.25G	$243	2021-12-16	Buy
Ambeed	A744788	1-(3-Chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethanone 95+%	1125812-58-9	5g	$255	2021-12-16	Buy
Crysdot	CD12179721	1-(3-Chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethanone 95+%	1125812-58-9	5g	$750	2021-12-16	Buy
Chemenu	CM274874	1-(3-Chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethanone 95+%	1125812-58-9	500g	$5520	2021-12-16	Buy

Product number	Packaging	Price	Buy
AS146793	1g	$120	Buy
HCH0361882	0.25G	$243	Buy
A744788	5g	$255	Buy
CD12179721	5g	$750	Buy
CM274874	500g	$5520	Buy

1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone Chemical Properties,Uses,Production

Uses

1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthesis

Synthesis_1125812-58-9
Cool the solution containing compound III (74.4g, 0.255mol containing compound III) to -100, and add 120g of sulfuric acid with a mass fraction of 92.5% to the above system while keeping the temperature below 0. After acidification, continue to react and keep for 1.5h, and then add 126.7g of 33% sodium nitrite aqueous solution (containing diazotizing reagent sodium nitrite 0.612mol) into the system uniformly within 2h, and keep the temperature at 0 The following reaction is carried out for 2 hours, and the system is heated to room temperature after full reaction, 111.1 g of 50% hypophosphorous acid and 0.67 g of cuprous oxide are added, and the reaction is stirred for 2 hours while keeping temperature. After the reaction is over, stand to separate the layers, and wash the organic layer with a 5% sodium bicarbonate aqueous solution, dry with anhydrous magnesium sulfate, and rectify to obtain a clear and transparent oily liquid 1-[3-chloro-5-(trifluoromethyl) (Yl)phenyl]-2,2,2-trifluoroethanone 66.9, content 99.5%, yield 87.2%.

1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone synthesis

Synthesis of 1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone from Ethyl trifluoroacetate and 3-Bromo-5-Chlorobenzotrifluoride

1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone Preparation Products And Raw materials

Raw materials

3-CHLORO-5-(TRIFLUOROMETHYL)BENZOYL CHLORIDE 3 - chloro - 5 - (trifluoroMethyl) benzene iodine 3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID Methyl 3-chloro-5-(trifluoroMethyl)benzoate 3-Bromo-5-Chlorobenzotrifluoride

2,2-Dimethyl-N-(4-trifluoromethyl-phenyl)-propionamid Ethyl trifluoroacetate Methyl trifluoroacetate 4-Aminobenzotrifluoride

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Preparation Products

1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone Suppliers

Global( 142)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29811	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10032	58
ENBRIDGE PHARMTECH CO., LTD.	+8613812269233	tinayang@enbridgepharm.com	China	322	58
Masteam Bio-tech Co., Ltd.	+86-15200345168 +86-15200345168	bruce.lei@masteam.com	CHINA	151	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30241	58
Win-Win chemical CO., Limited	+86-0086-577-64498589 +86-15355981851	sales@win-winchemical.com	China	14393	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Changzhou Ansciep Chemical Co., Ltd.	58
Hubei xin bonus chemical co. LTD	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Fuxin Pharmaceutical	58
ENBRIDGE PHARMTECH CO., LTD.	58
Masteam Bio-tech Co., Ltd.	58
Career Henan Chemica Co	58
Win-Win chemical CO., Limited	58

View Lastest Price from 1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2023-11-01	1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone 1125812-58-9	US $0.00-0.00 / kg	0.10000000149011612kg	98.0% min	1ton/month	Hangzhou ICH Biofarm Co., Ltd
	2020-01-15	1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone 1125812-58-9	US $1.00 / KG	1KG	99.0%	100kg	Career Henan Chemical Co

1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone
1125812-58-9
US $0.00-0.00 / kg
98.0% min
Hangzhou ICH Biofarm Co., Ltd

1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone
1125812-58-9
US $1.00 / KG
99.0%
Career Henan Chemical Co

1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone 3'-Chloro-5'-trifluoroMethyl-2,2,2-trifluoroacetophenone 2,2,2-trifluoro-3'-chloro-5'-trifluoromethylacetophenone 3'-Chloro-5'-trifluoromethoxy-2,2,2-trifluoroacetophenone Ethanone, 1-[3-chloro-5-(trifluoromethyl)phenyl]-2,2,2-trifluoro- 1-(3-chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethan-1-one (Afoxolaner intermediate） 1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone ISO 9001：2015 REACH afoxolaner-002 1-(3-chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethan-1-one afoxolaner Impurity 6 1-[3-Chloro-5-trifluoromethylphenyl 3'-Chloro-5'-trifluoromethoxy-2,2,2-trifluoroacetophenone 1125812-58-9 1123812-58-9