ChemicalBook >> CAS DataBase List >>FostaMatinib DisodiuM Hexahydrate
FostaMatinib DisodiuM Hexahydrate
- CAS No.
- 914295-16-2
- Chemical Name:
- FostaMatinib DisodiuM Hexahydrate
- Synonyms
- Fostamatinib Na;R788 (disodiuM hexahydrate);FostaMatinib DisodiuM Hexahydrate;Fostamatinib disodium salt hexahydrate;R788 Disodium Hexahydrate (Fostamatinib Disodium Hexahydrate);Fostamatinib Disodium Hexahydrate DISCONTINUED. Please see R070115.;6-[[5-Fluoro-2-[(3,4,5-triMethoxyphenyl)aMino]-4-pyriMidinyl]aMino]-2,2-diMethyl-4-[(phosphonooxy)Methyl]-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one SodiuM Salt Hydrate;Sodium (6-((5-fluoro-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)amino)-2,2-dimethyl-3-oxo-2,3-dihydro-4H-pyrido[3,2-b][1,4]oxazin-4-yl)methyl phosphate hexahydrate;6-[[5-Fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-4-[(phosphonooxy)methyl]-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one disodium salt hexahydrate;2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one, 6-[[5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-4-[(phosphonooxy)methyl]-, disodium salt, hexahydrate
- CBNumber:
- CB12545135
- Molecular Formula:
- C23H24FN6Na2O9P
- Molecular Weight:
- 624.4231642
- MDL Number:
- MOL File:
- 914295-16-2.mol
Last updated:2025-04-17 18:22:24
| storage temp. | Store at -20°C |
|---|---|
| solubility | Soluble in DMSO |
| form | Solid |
| color | White to gray |
| CAS DataBase Reference | 914295-16-2 |
| FDA UNII | 86EEZ49YVB |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P280-P305+P351+P338-P310 |
FostaMatinib DisodiuM Hexahydrate price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-2688 | Fostamatinib(disodiumhexahydrate) 99.92% | 914295-16-2 | 5mg | $96 | 2021-12-16 | Buy |
| ChemScene | CS-2688 | Fostamatinib(disodiumhexahydrate) 99.92% | 914295-16-2 | 10mg | $144 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FF23602 | Fostamatinib disodium hexahydrate | 914295-16-2 | 10mg | $225 | 2021-12-16 | Buy |
| ChemScene | CS-2688 | Fostamatinib(disodiumhexahydrate) 99.92% | 914295-16-2 | 50mg | $432 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0013911 | FOSTAMATINIB DISODIUM HEXAHYDRATE 95.00% | 914295-16-2 | 5MG | $463.1 | 2021-12-16 | Buy |
FostaMatinib DisodiuM Hexahydrate Chemical Properties,Uses,Production
Uses
A spleen tyrosine kinase inhibitor prodrug for the treatment of inflammatory diseases. An anti-inflammatory agent.
Uses
A spleen tyrosine kinase inhibitor prodrug for the treatment of inflammatory diseases.
in vivo
Fostamatinib (R788) is highly bioavailable, and rapidly absorbed in Louvain rats. R406 following a single oral dose of R788 10 mg/kg or 20 mg/kg: AUC0-16 hrs= 10618 ng*h/mL and 30650 ng*h/mL respectively; Cmax=2600 ng/mL and 6500 ng/mL respectively (observed at 1 hour); t1/2=4.2 hours. The prodrug was not detected in plasma suggesting R788 is completely converted to R406[1].
FostaMatinib DisodiuM Hexahydrate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 97)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8617531153977 | allison@yan-xi.com | China | 5854 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29730 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| TianYuan Pharmaceutical CO.,LTD | +86-755-23284190 13684996853 | sales@tianpharm.com | CHINA | 304 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29808 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10244 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9414 | 58 |
| Guangzhou TongYi biochemistry technology Co.,LTD | +8613073028829 | mack@tongyon.com | China | 2994 | 58 |
View Lastest Price from FostaMatinib DisodiuM Hexahydrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-25 | Fostamatinib Disodium Hexahydrate
914295-16-2
|
US $0.00-0.00 / g | 1g | 99% HPLC | 10000 | HangZhou RunYan Pharma Technology Co.,LTD. | |
 |
2025-03-07 | FostaMatinib DisodiuM Hexahydrate
914295-16-2
|
US $0.00 / kg | 1kg | 0.99 | 20tons | Hebei Yanxi Chemical Co., Ltd. | |
 |
2021-07-02 | Fostamatinib Disodium Hexahydrate
914295-16-2
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- Fostamatinib Disodium Hexahydrate
914295-16-2
- US $0.00-0.00 / g
- 99% HPLC
- HangZhou RunYan Pharma Technology Co.,LTD.
-
- FostaMatinib DisodiuM Hexahydrate
914295-16-2
- US $0.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
-
- Fostamatinib Disodium Hexahydrate
914295-16-2
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
914295-16-2(FostaMatinib DisodiuM Hexahydrate)Related Search:
FostaMatinib DisodiuM Hexahydrate
6-[[5-Fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-4-[(phosphonooxy)methyl]-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one disodium salt hexahydrate
Fostamatinib disodium salt hexahydrate
6-[[5-Fluoro-2-[(3,4,5-triMethoxyphenyl)aMino]-4-pyriMidinyl]aMino]-2,2-diMethyl-4-[(phosphonooxy)Methyl]-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one SodiuM Salt Hydrate
R788 (disodiuM hexahydrate)
Fostamatinib Na
2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one, 6-[[5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-4-[(phosphonooxy)methyl]-, disodium salt, hexahydrate
R788 Disodium Hexahydrate (Fostamatinib Disodium Hexahydrate)
Fostamatinib Disodium Hexahydrate
DISCONTINUED. Please see R070115.
Sodium (6-((5-fluoro-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)amino)-2,2-dimethyl-3-oxo-2,3-dihydro-4H-pyrido[3,2-b][1,4]oxazin-4-yl)methyl phosphate hexahydrate
914295-16-2
C23H26FN6O9P6H2O2Na
C23H36FN6Na2O15P
Phosphorylating and Phosphitylating Agents
Heterocycles
Intermediates & Fine Chemicals
Pharmaceuticals