Cyclopropyl carbinol
- CAS No.
- 2516-33-8
- Chemical Name:
- Cyclopropyl carbinol
- Synonyms
- CYCLOPROPYLMETHANOL;CYCLOPROPANEMETHANOL;CPMO;CP-CARBINOL;(HYDROXYMETHYL)CYCLOPROPANE;CPC-OL;Cyclopropylmethane;RARECHEM AK ML 0580;CYCLOPROPYL CARBINOL;CYCLPOPROPANEMETHANOL
- CBNumber:
- CB1254806
- Molecular Formula:
- C4H8O
- Molecular Weight:
- 72.11
- MDL Number:
- MFCD00001309
- MOL File:
- 2516-33-8.mol
| Melting point | -60 °C |
|---|---|
| Boiling point | 123-124 °C738 mm Hg(lit.) |
| Density | 0.89 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 95 °F |
| storage temp. | Flammables area |
| solubility | Chloroform, Ethyl Acetate |
| pka | 15.10±0.10(Predicted) |
| form | Liquid |
| color | Clear colorless |
| Specific Gravity | 0.890 |
| Water Solubility | miscible |
| BRN | 1846846 |
| InChIKey | GUDMZGLFZNLYEY-UHFFFAOYSA-N |
| CAS DataBase Reference | 2516-33-8(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| NIST Chemistry Reference | Cyclopropyl carbinol(2516-33-8) |
| EPA Substance Registry System | Cyclopropanemethanol (2516-33-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H226-H302-H319 | |||||||||
| Precautionary statements | P210-P301+P312+P330-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,Xi,C,F | |||||||||
| Risk Statements | 10-22-36-34 | |||||||||
| Safety Statements | 16-26-36-45-36/37/39 | |||||||||
| RIDADR | UN 1987 3/PG 3 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | GZ2212250 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29061990 | |||||||||
| NFPA 704 |
|
Cyclopropyl carbinol price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 482099 | Cyclopropanemethanol ≥99.5% | 2516-33-8 | 25ml | $67.8 | 2024-03-01 | Buy |
| Sigma-Aldrich | 482099 | Cyclopropanemethanol ≥99.5% | 2516-33-8 | 1l | $384.6 | 2024-03-01 | Buy |
| TCI Chemical | C0982 | Cyclopropanemethanol >98.0%(GC) | 2516-33-8 | 5mL | $20 | 2024-03-01 | Buy |
| TCI Chemical | C0982 | Cyclopropanemethanol >98.0%(GC) | 2516-33-8 | 25mL | $37 | 2024-03-01 | Buy |
| Alfa Aesar | A12567 | Cyclopropanemethanol, 98% | 2516-33-8 | 5g | $27.65 | 2024-03-01 | Buy |
Cyclopropyl carbinol Chemical Properties,Uses,Production
Description
Cyclopropyl carbinol (also known as Cyclopropanemethanol) is an anaesthetic. Cyclopropyl Carbinol is used as an intermediate for pharmaceuticals, agrochemical, and other organic synthesis such as for the applications for electronics chemicals, polymer additives, coatings, adhesives, surfactants, and other applications3. It can also be used for the preparation of cyclopropanecarbaldehyde, cyclopropylmethylsulfonate and dibenzyl cyclopropylmethyl phosphate1. It is also quite useful to for stereoselective synthesis of cycloalkene-fused butyrolactones via cyclopropylcarbinol solvolysis.
Referrence
Marshall, James A., and R. H. Ellison. "Stereoselective synthesis of cycloalkene-fused butyrolactones via cyclopropylcarbinol solvolysis." Journal of Organic Chemistry 40.14(1975):2070-2073.
Chemical Properties
Clear colorless liquid
Uses
Cyclopropanemethanol is used as an organic chemical synthesis intermediate.
Uses
Cyclopropylmethanol used to increase selectivity of pyridyl-cinnoline phosphodiesterase 10A, inhibitors against phosphodiesterase 3 (PDE3). Also used in the synthesis of benzodiazapin-2-ones
Preparation
The preparation of Cyclopropyl carbinol is as follows:A 1L three-necked flask was charged with 100 g (1mol) of methyl cyclopropanoate. 57g (1.5mol) of sodium borohydride, 500 mL of methanol, and then cooled to 2°C, 66.67g (0.5mol) of aluminum trichloride was added in batches and reacted overnight. The reaction was quenched by the addition of a saturated aqueous solution of ammonium chloride, filtered, and the filtrate was concentrated and evaporated. The product was collected in a yield of 53.49g, a yield of 74.3%.
General Description
Cyclopropanemethanol (Cyclopropyl carbinol, CPMO), a cycloalkanemethanol, is an anaesthetic. The coupling reaction of cyclopropanemethanol with alkynes to form substituted allylic alcohols has been reported. The microwave spectrum of CPMO has been recorded. Its rotational constants and dipole moment have been determined.
Cyclopropyl carbinol Preparation Products And Raw materials
Raw materials
Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2136 | 58 |
| Zhejiang Karry Pharmachem Co., Ltd. | +8613567161161 | info@karrypharma.com | China | 34 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8810 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12841 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20285 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Hangzhou FandaChem Co.,Ltd. | +8615858145714 | FandaChem@Gmail.com | China | 9206 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2986 | 55 |
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View Lastest Price from Cyclopropyl carbinol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-29 | Cyclopropyl carbinol
2516-33-8
|
US $0.00 / Kg/Drum | 1KG | 99%min | 1000KGS | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-10-28 | Cyclopropyl carbinol
2516-33-8
|
US $0.00-0.00 / KG | 1KG | 99% | 20 mt | Hebei Weibang Biotechnology Co., Ltd | |
 |
2024-02-26 | Cyclopropyl carbinol
2516-33-8
|
US $0.00-0.00 / kg | 1kg | 99% | Kgs | BTC Nantong Pharmaceuticals Technology Co.,Ltd |
-
- Cyclopropyl carbinol
2516-33-8
- US $0.00 / Kg/Drum
- 99%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Cyclopropyl carbinol
2516-33-8
- US $0.00-0.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd
-
- Cyclopropyl carbinol
2516-33-8
- US $0.00-0.00 / kg
- 99%
- BTC Nantong Pharmaceuticals Technology Co.,Ltd
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