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7-Ethyl-10-hydroxycaMptothecin

CAS No.
113015-38-6
Chemical Name:
7-Ethyl-10-hydroxycaMptothecin
Synonyms
CBNumber:
CB12562882
Molecular Formula:
C22H20N2O5
Molecular Weight:
392.4046
MDL Number:
MOL File:
113015-38-6.mol
Last updated:2023-05-04 17:34:31

7-Ethyl-10-hydroxycaMptothecin Chemical Properties,Uses,Production

Definition

ChEBI: SN-38 is a member of the class of pyranoindolizinoquinolines that is (4S)-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione bearing two additional ethyl substituents at positions 4 and 11 as well as two additional hydroxy substituents at positions 4 and 9. It is the active metabolite of irinotecan and is ~1000 times more active than irinotecan itself. It has a role as an apoptosis inducer, an EC 5.99.1.2 (DNA topoisomerase) inhibitor, a drug metabolite and an antineoplastic agent. It is a pyranoindolizinoquinoline, a delta-lactone, a tertiary alcohol and a member of phenols.

7-Ethyl-10-hydroxycaMptothecin Preparation Products And Raw materials

Raw materials

Preparation Products

7-Ethyl-10-hydroxycaMptothecin Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418684 +8618949823763 sales@tnjchem.com China 25363 58
Hangzhou Yuhao Chemical Technology Co., Ltd 0571-82693216 info@yuhaochemical.com China 9394 52
113015-38-6