Dimethyl 2-oxoglutarate
- CAS No.
- 13192-04-6
- Chemical Name:
- Dimethyl 2-oxoglutarate
- Synonyms
- Dimethyl 2-oxopentanedioate;1,5-diMethyl 2-oxopentanedioate;VINC-001;TUN-92046;GLutaconate;ethyl 2-oxoglutarate;DIMETHYL OXOGLUTARATE;DIMETHYL 2-OXOGLUTARATE;DIMETHYL 2-KETOGLUTARATE;Dimethyl α-ketoglutarate
- CBNumber:
- CB1262188
- Molecular Formula:
- C7H10O5
- Molecular Weight:
- 174.15
- MDL Number:
- MFCD00048052
- MOL File:
- 13192-04-6.mol
- MSDS File:
- SDS
| Boiling point | 90-95 °C0.4 mm Hg(lit.) |
|---|---|
| Density | 1.203 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | -20°C |
| solubility | DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 10 mg/ml |
| form | clear liquid |
| color | Colorless to Light yellow to Light orange |
| CAS DataBase Reference | 13192-04-6(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
| WGK Germany | 3 |
| HS Code | 29183000 |
Dimethyl 2-oxoglutarate price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 349631 | Dimethyl 2-oxoglutarate 96% | 13192-04-6 | 5g | $117 | 2024-03-01 | Buy |
| TCI Chemical | K0013 | Dimethyl 2-Oxoglutarate >95.0%(GC) | 13192-04-6 | 5mL | $101 | 2024-03-01 | Buy |
| TCI Chemical | K0013 | Dimethyl 2-Oxoglutarate >95.0%(GC) | 13192-04-6 | 25mL | $269 | 2024-03-01 | Buy |
| TRC | D474425 | Dimethyl2-Ketoglutaconate | 13192-04-6 | 1g | $50 | 2021-12-16 | Buy |
| TRC | D474425 | Dimethyl2-Ketoglutaconate | 13192-04-6 | 50g | $730 | 2021-12-16 | Buy |
Dimethyl 2-oxoglutarate Chemical Properties,Uses,Production
Chemical Properties
Slight Yellow Liquid
Uses
Dimethyl 2-oxoglutarate may be used to synthesize the conformationally constrained PNA (peptide nucleic acid) -monomer capable of binding thymine in a triplex motif. It may be used in the synthesis of 4-aryl kainic acid analogs, via highly stereoselective Michael addition reaction with nitrostyrene.
Definition
ChEBI: Dimethyl 2-oxoglutarate is an oxo carboxylic acid.
General Description
Dimethyl 2-oxoglutarate is a key intermediate formed during the Krebs cycle and an important nitrogen transporter in the biological metabolic pathways. The electrochemical behavior of dimethyl-2-oxoglutarate has been investigated by cyclic voltammetry, square wave voltammetry and differential pulse voltammetry using a glassy carbon electrode.
in vivo
Dimethyl 2-oxoglutarate (i.p.) decreases cardiac maladaptive autophagy induced by thoracic aortic constriction (TAC), ameliorating TAC-induced pathological remodeling, ventricular hypertrophy and fibrosis, and reduction in contractile performance in mice[3].
IC 50
Microbial Metabolite
Dimethyl 2-oxoglutarate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29730 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21628 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29858 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 | info@edengenechem.com | China | 2176 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
| Jinan Liheng Biotechnology Co., Ltd. | 15865262812 | info@lihengpharm.com | CHINA | 938 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32202 | 58 |
Related articles
- Dimethyl 2-ketoglutarate:Physiological effects and Electrochemical behaviour
- Dimethyl 2-ketoglutarate is an esterified form of the citric acid cycle intermediate α-ketoglutarate.
- Dec 12，2024
View Lastest Price from Dimethyl 2-oxoglutarate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-28 | TUN-92046
13192-04-6
|
US $0.00 / removed | 97.63% | 10g | TargetMol Chemicals Inc. | ||
 |
2021-08-12 | Dimethyl 2-oxoglutarate
13192-04-6
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2019-08-06 | Dimethyl 2-oxoglutarate
13192-04-6
|
US $8.80 / KG | 1KG | 97%-99% | 100kg | Career Henan Chemical Co |
-
- TUN-92046
13192-04-6
- US $0.00 / removed
- 97.63%
- TargetMol Chemicals Inc.
-
- Dimethyl 2-oxoglutarate
13192-04-6
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Dimethyl 2-oxoglutarate
13192-04-6
- US $8.80 / KG
- 97%-99%
- Career Henan Chemical Co