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ChemicalBook >> CAS DataBase List >>2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)-

2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)-

2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)- Structure
2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)- structure
CAS No.
779353-02-5
Chemical Name:
2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)-
Synonyms
CDK-IN-6;CDK IN 6,CDKIN6;2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)-;(S)-2-(1-(3-ethyl-7-((pyridin-3-ylmethyl)amino)pyrazolo[1,5-a]pyrimidin-5-yl)piperidin-2-yl)ethanol
CBNumber:
CB12667765
Molecular Formula:
C21H28N6O
Molecular Weight:
380.48662
MDL Number:
MFCD28167881
MOL File:
779353-02-5.mol
Last updated:2024-07-02 08:55:00
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2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)- Properties

Density 1.29±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 50 mg/mL (131.41 mM; Need ultrasonic)
form Solid
pka 15.15±0.10(Predicted)
color Light yellow to brown

2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Chemenu CM331253 (S)-2-(1-(3-ethyl-7-((pyridin-3-ylmethyl)amino)pyrazolo[1,5-a]pyrimidin-5-yl)piperidin-2-yl)ethanol 95%+ 779353-02-5 100mg $864 2021-12-16 Buy
Chemenu CM331253 (S)-2-(1-(3-ethyl-7-((pyridin-3-ylmethyl)amino)pyrazolo[1,5-a]pyrimidin-5-yl)piperidin-2-yl)ethanol 95%+ 779353-02-5 250mg $1680 2021-12-16 Buy
Product number Packaging Price Buy
CM331253 100mg $864 Buy
CM331253 250mg $1680 Buy

2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)- Chemical Properties,Uses,Production

Biological Activity

CDK-IN-6, a class of pyrazolo[1,5-a]pyrimidine compound, is a CDK inhibitor with anticancer activities[1]. Individual CDK’s, such as, CDK1, CDK2, CDK3, CDK4, CDK5, CDK6 and CDK7, CDK8 and the like, perform distinct roles in cell cycle progression and can be classified as either G1, S, or G2M phase enzymes. Uncontrolled proliferation is a hallmark of cancer cells, and misregulation of CDK function occurs with high frequency in many important solid tumors[1].

References

[1]. Timothy Guzi, et al. Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors. US20040209878A1.

2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)- Preparation Products And Raw materials

Raw materials

Preparation Products

2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)- Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanjing Bicbiotechnology Co., Ltd 		+86-2552131256 +86-18251840740 sales@bicbiotech.com China 6000 58
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7553 61
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 sales-cpd@caerulumpharma.com China 3431 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Nanjing Bic Biotechnology Co., Ltd 025-58906079 sales@bicbiotech.com China 6538 58
Supplier Advantage
Nanjing Bicbiotechnology Co., Ltd 		58
Haoyuan Chemexpress Co., Ltd. 61
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
TargetMol Chemicals Inc. 58
Nanjing Bic Biotechnology Co., Ltd 58
2-Piperidineethanol, 1-[3-ethyl-7-[(3-pyridinylMethyl)aMino]pyrazolo[1,5-a]pyriMidin-5-yl]-, (2S)- (S)-2-(1-(3-ethyl-7-((pyridin-3-ylmethyl)amino)pyrazolo[1,5-a]pyrimidin-5-yl)piperidin-2-yl)ethanol CDK-IN-6 CDK IN 6,CDKIN6 779353-02-5