ChemicalBook >> CAS DataBase List >>(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride

(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride

CAS No.
874460-46-5
Chemical Name:
(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride
Synonyms
Aprepitant Impurity 3 HCl;Aprepitant Impurity 7 HCl;Aprepitant Impurity SM3QF;Des-(4-fluoro-1,2,4-triazol-3-one-5-methyl (2R,3S,1'S)-Aprepitant Hydrochloride;(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine hydrochloride;(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride;(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine hydrochloride (Aprepitant Impurity)
CBNumber:
CB12669002
Molecular Formula:
C20H20ClF6NO2
Molecular Weight:
455.83
MDL Number:
MOL File:
874460-46-5.mol
Last updated:2024-06-11 19:18:13

(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride Chemical Properties,Uses,Production

Uses

Des-(4-fluoro-1,2,4-triazol-3-one-5-methyl (2R,3S,1''S)-Aprepitant Hydrochloride is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.

(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride Suppliers

Global( 27)Suppliers
Supplier Tel Email Country ProdList Advantage
China National Standard Pharmaceutical Corporation Limited
+8615391658522 overseasales@yongstandards.com China 11922 58
ShenZhen H&D Pharmaceutical Technology Co., LTD
+8618627948422 sale@hdimpurity.com China 3389 58
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14055 65
Shanghai Ranxon Chemical Co., Ltd. 13148101715 2073632910@qq.com China 38 55
Nanjing XiZe Biotechnology CO., Ltd. 025-66023220 0086-15250997978 1511893459@qq.com China 7850 55
BOC Sciences 16314854226 info@bocsci.com United States 9923 65
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@qq.com China 8377 55
Jinan blalong chemical co. LTD 2710913286@.com 1513643261@qq.com China 14246 58
Cato Research Chemicals Inc. 020-81215950 4000-868-328 customer@uwalab.com United States 10404 58
SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD 0755-0755-0755-83725350 13380397412 3001280422@qq.com China 10005 58

View Lastest Price from (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Aprepitant Impurity 36 pictures 2024-09-20 Aprepitant Impurity 36
874460-46-5
US $0.00-0.00 / mg 10mg 98% 500mg ShenZhen H&D Pharmaceutical Technology Co., LTD
(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride Aprepitant Impurity 3 HCl Des-(4-fluoro-1,2,4-triazol-3-one-5-methyl (2R,3S,1'S)-Aprepitant Hydrochloride Aprepitant Impurity SM3QF Aprepitant Impurity 7 HCl (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine hydrochloride (Aprepitant Impurity) (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine hydrochloride 874460-46-5