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ChemicalBook >> CAS DataBase List >>(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride

(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride

(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride Structure
(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride structure
CAS No.
874460-46-5
Chemical Name:
(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride
Synonyms
Aprepitant Impurity 3 HCl;Aprepitant Impurity 7 HCl;Aprepitant Impurity SM3QF;Des-(4-fluoro-1,2,4-triazol-3-one-5-methyl (2R,3S,1'S)-Aprepitant Hydrochloride;(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine hydrochloride;(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride;(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine hydrochloride (Aprepitant Impurity)
CBNumber:
CB12669002
Molecular Formula:
C20H20ClF6NO2
Molecular Weight:
455.83
MDL Number:
MOL File:
874460-46-5.mol
Last updated:2024-06-11 19:18:13
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(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride Chemical Properties,Uses,Production

Uses

Des-(4-fluoro-1,2,4-triazol-3-one-5-methyl (2R,3S,1''S)-Aprepitant Hydrochloride is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.

(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride Suppliers

Global( 25)Suppliers
Supplier Tel Email Country ProdList Advantage
China National Standard Pharmaceutical Corporation Limited 		+8615391658522 overseasales@yongstandards.com China 11927 58
ShenZhen H&D Pharmaceutical Technology Co., LTD 		+86-0755-22677845 +86-13627253706 sale@hdimpurity.com China 3389 58
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
Shanghai Ranxon Chemical Co., Ltd. 13148101715 2073632910@qq.com China 38 55
Nanjing XiZe Biotechnology CO., Ltd. 025-66023220 0086-15250997978 1511893459@qq.com China 7774 55
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@qq.com China 8286 55
Jinan blalong chemical co. LTD 2710913286@.com 1513643261@qq.com China 14253 58
Cato Research Chemicals Inc. 020-81215950 4000-868-328 customer@uwalab.com United States 10413 58
SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD 0755-0755-0755-83725350 13380397412 3001280422@qq.com China 10044 58
Supplier Advantage
China National Standard Pharmaceutical Corporation Limited 		58
ShenZhen H&D Pharmaceutical Technology Co., LTD 		58
BOC Sciences 65
Shanghai Ranxon Chemical Co., Ltd. 55
Nanjing XiZe Biotechnology CO., Ltd. 55
BOC Sciences 65
Hubei Yangxin Medical Technology Co., Ltd. 55
Jinan blalong chemical co. LTD 58
Cato Research Chemicals Inc. 58
SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD 58

View Lastest Price from (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Aprepitant Impurity 36 pictures 2024-08-22 Aprepitant Impurity 36
874460-46-5
 US $0.00-0.00 / mg 10mg 98% 500mg ShenZhen H&D Pharmaceutical Technology Co., LTD

874460-46-5((2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride)Related Search:

Aprepitant 5-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Fosaprepitant Benzyl dihydrogen phosphate
(2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine (2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine Fosaprepitant Benzyl Ester (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride
ent-Aprepitant 5-(hydroxymethyl)-1,2-dihydro-1,2,4-triazol-3-one (R,R,R)-Aprepitant (1S,2S,3R)-Aprepitant Aprepitant
Defluoro Aprepitant Aprepitant Impurity B HCl Aprepitant Impurity 11 HCl

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(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride Aprepitant Impurity 3 HCl Des-(4-fluoro-1,2,4-triazol-3-one-5-methyl (2R,3S,1'S)-Aprepitant Hydrochloride Aprepitant Impurity SM3QF Aprepitant Impurity 7 HCl (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine hydrochloride (Aprepitant Impurity) (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine hydrochloride 874460-46-5