3-(1-Methylethyl)-6-(phenylMethyl)-2(1H)-pyrazinone
- CAS No.
- 170713-71-0
- Chemical Name:
- 3-(1-Methylethyl)-6-(phenylMethyl)-2(1H)-pyrazinone
- Synonyms
- Aureusimine B;6-BENZYL-3-ISOPROPYLPYRAZIN-2-ONE;6-benzyl-3-isopropylpyrazin-2(1H)-one;3-(1-Methylethyl)-6-(phenylMethyl)-2(1H)-pyrazinone;2(1H)-Pyrazinone, 3-(1-methylethyl)-6-(phenylmethyl)-
- CBNumber:
- CB12682115
- Molecular Formula:
- C14H16N2O
- Molecular Weight:
- 228.28964
- MDL Number:
- MFCD00930483
- MOL File:
- 170713-71-0.mol
3-(1-Methylethyl)-6-(phenylMethyl)-2(1H)-pyrazinone price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 18752 | Aureusimine B ≥95% | 170713-71-0 | 1mg | $214 | 2024-03-01 | Buy |
| Cayman Chemical | 18752 | Aureusimine B ≥95% | 170713-71-0 | 5mg | $957 | 2024-03-01 | Buy |
| TRC | A794570 | AureusimineB | 170713-71-0 | 5mg | $185 | 2021-12-16 | Buy |
| AK Scientific | 7138CR | 6-Benzyl-3-isopropyl-2(1H)-pyrazinone | 170713-71-0 | 5mg | $1163 | 2021-12-16 | Buy |
| Crysdot | CD11237706 | 6-Benzyl-3-isopropylpyrazin-2(1H)-one 95+% | 170713-71-0 | 50mg | $1131 | 2021-12-16 | Buy |
3-(1-Methylethyl)-6-(phenylMethyl)-2(1H)-pyrazinone Chemical Properties,Uses,Production
Description
Aureusimine B, also known as phevalin, is a natural pyrazinone produced by certain fungi and by Staphylococcus spp., including S. aureus. Its synthesis appears to be initiated by a conserved nonribosomal peptide synthetase that creates a dipeptide (phenylalanine-valine) aldehyde, which then undergoes cyclization and oxidation. Aureusimine B inhibits calpain in a casein hydrolysis assay (IC50 = 1.3 μM), contributes to S. aureus infection in mice, and alters human keratinocyte gene expression.
Uses
Aureusimine B is a novel small molecule isolated from S. aureus as one of a pair of related metabolites controversially identified as virulence factors in the pathology of Golden Staph. Aureusimine B has also been reported as an inhibitor of the protease, calpain.
Uses
Aureusimine B (phevalin) is a small molecular weight monoketopiperazine formed non-ribosomally by the fusion of phenylalanine and valine. Aureusimine B was isolated from S. aureus in 2010 as one of a pair of related metabolites, controversially identified as virulence factors in the pathology of Golden Staph. Aureusimine B is also an inhibitor of the protease, calpain.
Definition
ChEBI: Phevalin is a member of the class of pyrazinones that is pyrazin-2(1H)-one substituted by an isopropyl and benzyl groups at position 3 and 6, respectively. It is a natural product found in Staphylococcus aureus that inhibits calpain in a casein hydrolysis assay (IC50 = 1.3 muM), contributes to S. aureus infection in mice, and alters human keratinocyte gene expression. It has a role as a bacterial metabolite and a calpain inhibitor. It is a member of benzenes and a pyrazinone.
3-(1-Methylethyl)-6-(phenylMethyl)-2(1H)-pyrazinone Preparation Products And Raw materials
Raw materials
Preparation Products
3-(1-Methylethyl)-6-(phenylMethyl)-2(1H)-pyrazinone Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19741 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38632 | 58 | |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| AstaTech (Chengdu) Pharma. Co., Ltd. | 028-85122536 15928766785 | wupengcheng@astatech.cn | China | 2000 | 55 |
| SanoChem (Chengdu) Tech. Co., Ltd. | 28-87999436 02887999436 | sales@sano-chem.com | China | 3795 | 55 |
| Lynnchem | 86-(0)29-85992781 17792393971 | info@lynnchem.com | China | 4587 | 58 |
| Nanjing KaiMubo Pharmaceutical Co., Ltd. | 025-66162170 | China | 7181 | 55 | |
| Novachemistry | 44-20819178-90 02081917890 | info@novachemistry.com | United Kingdom | 4381 | 58 |
| Shanghai He Huan Chemical Co., Ltd. | 021-60345187 13917602471 | lzz841106@aliyun.com | China | 9897 | 58 |
View Lastest Price from 3-(1-Methylethyl)-6-(phenylMethyl)-2(1H)-pyrazinone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | Aureusimine B
170713-71-0
|
US $89.00-197.00 / mg | 99.9% | 10g | TargetMol Chemicals Inc. |
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- Aureusimine B
170713-71-0
- US $89.00-197.00 / mg
- 99.9%
- TargetMol Chemicals Inc.