ChemicalBook >> CAS DataBase List >>(2'S)-2'-Deoxy-2'-fluoro-5-ethynyluridine

(2'S)-2'-Deoxy-2'-fluoro-5-ethynyluridine

CAS No.
95740-26-4
Chemical Name:
(2'S)-2'-Deoxy-2'-fluoro-5-ethynyluridine
Synonyms
F-ara-EdU;(2'S)-2'-Deoxy-2'-fluoro-5-ethynyluridine;1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethynyluracil;1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethynyluracil;2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethynyl-
CBNumber:
CB12694455
Molecular Formula:
C11H11FN2O5
Molecular Weight:
270.22
MDL Number:
MFCD22417248
MOL File:
95740-26-4.mol
Last updated:2023-06-26 08:28:19

(2'S)-2'-Deoxy-2'-fluoro-5-ethynyluridine Properties

Density 1.60±0.1 g/cm3(Predicted)
pka 8.29±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H300+H310+H330
Precautionary statements  P260-P262-P264-P280-P302+P352+P310-P304+P340+P310

(2'S)-2'-Deoxy-2'-fluoro-5-ethynyluridine price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T511293 (2′S)-2′-Deoxy-2′-fluoro-5-ethynyluridine, (F-ara-EdU) AldrichCPR 95740-26-4 5MG $173 2023-06-20 Buy
TRC D232980 (2’S)-2’-Deoxy-2’-fluoro-5-ethynyluridine 95740-26-4 10mg $185 2021-12-16 Buy
Product number Packaging Price Buy
T511293 5MG $173 Buy
D232980 10mg $185 Buy

(2'S)-2'-Deoxy-2'-fluoro-5-ethynyluridine Chemical Properties,Uses,Production

Uses

(2′S)-2′-Deoxy-2′-fluoro-5-ethynyluridine is a commonly used probe for DNA synthesis in vivo as it exhibits minimal impact on genome function in diverse tissue types. (2′S)-2′-deoxy-2′-fluoro-5-ethynyluridine is also ideally suited for metabolic DNA labeling when prolonged cell survival and undisturbed cell cycle progression are necessary, such as for pulse-chase experiments aimed at “birth dating” DNA in vivo.

Uses

A probe for DNA synthesis in vivo that is less toxic than both EdU and BrdU. Ideally suited for metabolic DNA labeling when prolonged cell survival and undisturbed cell cycle progression are required.

95740-25-3
95740-26-4
Synthesis of (2'S)-2'-Deoxy-2'-fluoro-5-ethynyluridine from 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-[(trimethylsilyl)ethynyl]- (9CI)

(2'S)-2'-Deoxy-2'-fluoro-5-ethynyluridine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 14)Suppliers
Supplier Tel Email Country ProdList Advantage
NewCan Biotech Limited
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Aladdin Scientific
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J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979 info@tsbiochem.com China 8073 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 56070 58
BOC Sciences 16314854226 inquiry@bocsci.com United States 9713 58
Hangzhou FuRun Pharmaceutical Technology Co., Ltd 15658004993 1900830611@qq.com China 959 58
Jiangsu Nanchuang Chemical and Life Health Research Institute Co., Ltd. +86-13857751219; 15720605021 zhang_lei@jsnchem.com China 1547 58
Beijing Qinling Pharmaceutical Co., Ltd. 010-61241352 18901327973 sales@qlmed.com China 4173 58
Shanghai Tachizaki Biomedical Research Center 18014399201 sales@chemlab-tachizaki.com China 2532 58
(2'S)-2'-Deoxy-2'-fluoro-5-ethynyluridine 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethynyluracil F-ara-EdU 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethynyl- 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethynyluracil 95740-26-4 Carbohydrates & Derivatives, Heterocycles, Nucleotides, Bases & Related Reagents