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GSK 2330672

GSK 2330672 Structure
GSK 2330672 structure
CAS No.
1345982-69-5
Chemical Name:
GSK 2330672
Synonyms
linerixibat;CS-2639;Iinerixibat;GSK 2330672;Iinerixibat (GSK2330672);linerixibat (GSK2330672);GSK 2330672; GSK-2330672;3-((((3R,5R)-3-Butyl-3-ethyl-7-methoxy-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[f][1,4]thiazepin-8-yl)methyl)amino)pentanedioic acid;Pentanedioic acid, 3-((((3R,5R)-3-butyl-3-ethyl-2,3,4,5-tetrahydro-7-methoxy-1,1-dioxido-5-phenyl-1,4-benzothiazepin-8-yl)methyl)amino)-;3-[[(3R,5R)-3-butyl-3-ethyl-7-methoxy-1,1-dioxo-5-phenyl-4,5-dihydro-2H-1λ6,4-benzothiazepin-8-yl]methylamino]pentanedioic acid
CBNumber:
CB12716247
Molecular Formula:
C28H38N2O7S
Molecular Weight:
546.68
MDL Number:
MFCD28386358
MOL File:
1345982-69-5.mol
MSDS File:
SDS
Last updated:2024-11-19 15:53:33
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GSK 2330672 Properties

Boiling point 730.8±60.0 °C(Predicted)
Density 1.218±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 5 mg/ml; DMSO: 2 mg/ml; PBS (pH 7.2): 0.2 mg/ml
form A crystalline solid
pka 3.27±0.10(Predicted)
color White to off-white
FDA UNII 386012Z45S

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS09
Signal word  Warning
Hazard statements  H302-H315-H319-H335-H401-H411
Precautionary statements  P261-P264-P270-P271-P273-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P391-P403+P233-P405-P501
NFPA 704
0
2 0

GSK 2330672 price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 23843 GSK2330672 ≥98% 1345982-69-5 1mg $110 2024-03-01 Buy
Cayman Chemical 23843 GSK2330672 ≥98% 1345982-69-5 5mg $515 2024-03-01 Buy
Cayman Chemical 23843 GSK2330672 ≥98% 1345982-69-5 10mg $918 2024-03-01 Buy
AK Scientific 4578DL Linerixibat 1345982-69-5 5mg $671 2021-12-16 Buy
Crysdot CD31003808 GSK2330672 98+% 1345982-69-5 5mg $208 2021-12-16 Buy
Product number Packaging Price Buy
23843 1mg $110 Buy
23843 5mg $515 Buy
23843 10mg $918 Buy
4578DL 5mg $671 Buy
CD31003808 5mg $208 Buy

GSK 2330672 Chemical Properties,Uses,Production

Description

GSK2330672 is an inhibitor of the apical sodium-dependent bile acid transporter (ASBT; IC50s = 42, 2.1, and 1.9 nM for human, mouse, and rat ASBT, respectively). In vivo, GSK2330672 (0.05 mg/kg) stimulates fecal bile acid secretion, reduces hemoglobin A1c (HbA1c) and plasma glucose levels, and increases total GLP-1 and plasma insulin in Zucker diabetic fatty (ZDF) rats.

GSK 2330672 Preparation Products And Raw materials

Raw materials

Preparation Products

GSK 2330672 Suppliers

Global( 67)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32957 60
Biochempartner 		0086-13720134139 candy@biochempartner.com CHINA 965 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 8497 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30240 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10473 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38632 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8467 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Biochempartner 		58
Jinan Carbotang Biotech Co.,Ltd. 		58
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
Zhejiang J&C Biological Technology Co.,Limited 		58
InvivoChem 		58
TargetMol Chemicals Inc. 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58

View Lastest Price from GSK 2330672 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Linerixibat pictures 2024-11-19 Linerixibat
1345982-69-5
 US $76.00-222.00 / mg 99.83% 10g TargetMol Chemicals Inc.
  • Linerixibat pictures
  • Linerixibat
    1345982-69-5
  • US $76.00-222.00 / mg
  • 99.83%
  • TargetMol Chemicals Inc.

1345982-69-5(GSK 2330672)Related Search:

GSK2814338 GSK-2256098 GSK-25 S)-1-(sec-butyl)-N-((4,6-diMethyl-2-oxo-1,2-dihydropyridin-3-yl)Methyl)-3-Methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxaMide 7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyriMidin-4-aMine
GSK 2801 GSK2636771 GSK2879552 GSK2795039 GSK2838232

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GSK 2330672 GSK 2330672; GSK-2330672 3-[[(3R,5R)-3-butyl-3-ethyl-7-methoxy-1,1-dioxo-5-phenyl-4,5-dihydro-2H-1λ6,4-benzothiazepin-8-yl]methylamino]pentanedioic acid Pentanedioic acid, 3-((((3R,5R)-3-butyl-3-ethyl-2,3,4,5-tetrahydro-7-methoxy-1,1-dioxido-5-phenyl-1,4-benzothiazepin-8-yl)methyl)amino)- CS-2639 Iinerixibat Iinerixibat (GSK2330672) linerixibat type-2,PBC,lipid-lowering,solubility,nonabsorbable,GSK-2330672,Inhibitor,Primary,diabetes,GSK 2330672,Cholangitis,inhibit,Linerixibat,aqueous,Biliary,ASBT linerixibat (GSK2330672) 3-((((3R,5R)-3-Butyl-3-ethyl-7-methoxy-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[f][1,4]thiazepin-8-yl)methyl)amino)pentanedioic acid 1345982-69-5