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TRV 130

TRV 130 Structure
TRV 130 structure
CAS No.
1401028-24-7
Chemical Name:
TRV 130
Synonyms
Olinvo;TRV 130;Oliceridine;oliceridine,TRV-130;TRV130 (Oliceridine);OLINVO;TRV130;TRV-130;Foscarbidopa Impurity 22;TRV 130; TRV-130; OLICERIDINE;(9R)-N-[(3-Methoxy-2-thienyl)methyl]-9-(2-pyridinyl)-6-oxaspiro[4.5]decane-9-ethanamine;(R)-N-[(3-Methoxy-2-thienyl)methyl]-2-[9-(2-pyridyl)-6-oxaspiro[4.5]decan-9-yl]ethanamine
CBNumber:
CB12716393
Molecular Formula:
C22H30N2O2S
Molecular Weight:
386.55
MDL Number:
MFCD28385855
MOL File:
1401028-24-7.mol
MSDS File:
SDS
Last updated:2023-07-21 14:17:16

TRV 130 Properties

Boiling point 526.5±45.0 °C(Predicted)
Density 1.17±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : ≥ 38 mg/mL (89.83 mM)
pka 8.38±0.19(Predicted)
FDA UNII MCN858TCP0

TRV 130 Chemical Properties,Uses,Production

Uses

TRV-130 is used for drug discovery and designing ideal opioids in pharmacological activity, therapeutic use, and biological study.

TRV 130 synthesis

1401031-38-6
1401028-24-7
Synthesis of TRV 130 from 2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetonitrile

TRV 130 Preparation Products And Raw materials

Raw materials

2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetaldehyde 2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetonitrile Cyclopentanone

Preparation Products

TRV 130 Oliceridine (9R)-N-[(3-Methoxy-2-thienyl)methyl]-9-(2-pyridinyl)-6-oxaspiro[4.5]decane-9-ethanamine TRV 130; TRV-130; OLICERIDINE TRV130 (Oliceridine) Olinvo OLINVO;TRV130;TRV-130 oliceridine,TRV-130 N-[(3-methoxythiophen-2-yl)methyl]-2-[(9R)-9-pyridin-2-yl-6-oxaspiro[4.5]decan-9-yl]ethanamine 6-Oxaspiro[4.5]decane-9-ethanamine, N-[(3-methoxy-2-thienyl)methyl]-9-(2-pyridinyl)-, (9R)- (R)-N-[(3-Methoxy-2-thienyl)methyl]-2-[9-(2-pyridyl)-6-oxaspiro[4.5]decan-9-yl]ethanamine Foscarbidopa Impurity 22 1401028-24-7