ChemicalBook >> CAS DataBase List >>D-erythro-sphinganine-d7

D-erythro-sphinganine-d7

CAS No.
1246304-35-7
Chemical Name:
D-erythro-sphinganine-d7
Synonyms
sphinganine-d7;Sphinganine-d7 (d18:0);D-erythro-sphinganine-d7;D-ERYTHRO-SPHINGANINE-D7;SPHINGANINE-D7
CBNumber:
CB12719824
Molecular Formula:
C18H39NO2
Molecular Weight:
301.52
MDL Number:
MFCD22416901
MOL File:
1246304-35-7.mol
Last updated:2024-07-02 08:55:00

D-erythro-sphinganine-d7 Properties

solubility DMF: 10 mg/mL; DMSO: 2 mg/mL; Ethanol: miscible
form A crystalline solid
color White to off-white

D-erythro-sphinganine-d7 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 27145 Sphinganine-d7 (d18:0) 1246304-35-7 500μg $125 2024-03-01 Buy
Cayman Chemical 27145 Sphinganine-d7 (d18:0) 1246304-35-7 1mg $237 2024-03-01 Buy
Product number Packaging Price Buy
27145 500μg $125 Buy
27145 1mg $237 Buy

D-erythro-sphinganine-d7 Chemical Properties,Uses,Production

Description

Sphinganine-d7 (d18:0) is intended for use as an internal standard for the quantification of sphinganine (d18:0) by GC- or LC-MS. Sphinganine (d18:0) is a precursor to ceramide and sphingosine as well as a substrate of sphingosine kinases, which generate sphinganine-1-phosphate .1 Sphinganine (d18:0) levels increase significantly in response to certain mycotoxins, including fumonisins, as well as in some cancers.2,3,4

References

1. Smith, E.R., and Merrill, A.H., Jr. Differential roles of de novo sphingolipid biosynthesis and turnover in the “Burst” of free sphingosine and sphinganine, and their 1-phosphates and N-acyl-derivatives, that occurs upon changing the medium of cells in culture J. Biol. Chem. 270(32),18749-18758(1995).
2. Pruett, S.T., Bushnev, A., Hagedorn, K., et al. Biodiversity of sphingoid bases ("sphingosines") and related amino alcohols J. Lipid Res. 49(8),1621-1639(2008).
3. Shephard, G.S., van der Westhuizen, L., and Sewram, V. Biomarkers of exposure to fumonisin mycotoxins: A review Food Addit. Contam. 24(10),1196-1201(2007).
4. Yin, J., Miyazaki, K., Shaner, R.L., et al. Altered sphingolipid metabolism induced by tumor hypoxia - new vistas in glycolipid tumor markers FEBS Lett. 584(9),1872-1878(2010).

D-erythro-sphinganine-d7 Preparation Products And Raw materials

Raw materials

Preparation Products

D-erythro-sphinganine-d7 Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Codow Chemical Co.,Ltd. 18620099427 amy@howeipharm.com China 17698 55
Chengdu Dianchun Technology Co., Ltd 400-1166-196 18502815961 cdhxsj@163.com China 14623 60
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8739 58
D-erythro-sphinganine-d7 D-ERYTHRO-SPHINGANINE-D7;SPHINGANINE-D7 sphinganine-d7 Sphinganine-d7 (d18:0) 1246304-35-7