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(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID

(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID structure

CAS No.: 16626-02-1

Chemical Name:: (S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID

Synonyms: L-Trp(5-F)-OH;H-L-Trp(5-F)-OH*H2O;L-5-FLUOROTRYPTOPHAN;5-FLUORO-L-TRYPTOPHAN;H-5-FLUORO-TRP-OH H2O;Tryptophan Impurity 54;5-fluoro-L-tryptophans;L-Tryptophan, 5-fluoro-;5-Fluoro-tryptophan monohydrate;L-5-fluorotryptophan monohydrate

CBNumber:: CB1274150

Molecular Formula:: C11H11FN2O2

Molecular Weight:: 222.22

MDL Number:: MFCD00066470

MOL File:: 16626-02-1.mol

MSDS File:: SDS

Last updated:2022-12-30 16:20:48

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(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Properties

Melting point	238-239 °C
Boiling point	450.7±45.0 °C(Predicted)
Density	1.442±0.06 g/cm3(Predicted)
storage temp.	2-8°C
pka	2.21±0.10(Predicted)
BRN	5052680
FDA UNII	17H03VO4KZ

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P305+P351+P338
Safety Statements	22-24/25
WGK Germany	3
F	10
HS Code	2933998090

(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID price More Price(20)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	47568	5-Fluoro-L-tryptophan ≥98.0% (HPLC)	16626-02-1	25mg	$186	2024-03-01	Buy
Apolloscientific	PC530031	5-Fluoro-L-tryptophan 97%	16626-02-1	1g	$600	2021-12-16	Buy
Activate Scientific	AS87334	5-Fluoro-L-tryptophan 95+% ee	16626-02-1	5G	$1349	2021-12-16	Buy
AK Scientific	8456AA	(S)-2-Amino-3-(5-fluoro-1H-indol-3-yl)propanoicacid	16626-02-1	5g	$2650	2021-12-16	Buy
Activate Scientific	AS87334	5-Fluoro-L-tryptophan 95+% ee	16626-02-1	1g	$491	2021-12-16	Buy

Product number	Packaging	Price	Buy
47568	25mg	$186	Buy
PC530031	1g	$600	Buy
AS87334	5G	$1349	Buy
8456AA	5g	$2650	Buy
AS87334	1g	$491	Buy

(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Chemical Properties,Uses,Production

Uses

Exogenous 5-fluoro-Trp is incorporated into proteins in normal protein synthesis. Since ¹⁹F is a useful reporter group, this provides a method for studying enzyme mechanisms by NMR.

Biochem/physiol Actions

5-Fluoro-Trp is nonspecifically cytotoxic. It is believed this is due to malfunctioning enzymes that have had replacements of Trp residues by 5-fluoro-Trp. However, at least one case is known where 5-fluoro-Trp substitution leads to significantly greater catalytic activity.

Purification Methods

Recrystallise it from EtOH, aqueous EtOH or AcOH. Also purify it by passage through a Dowex AG1x2 (acetate form) column and recrystallise the L-enantiomer (from enzymic enrichment) from H2O/EtOH, m 158-163o(dec), [] D -8.3o (c 2.5, N NaOH). [Coy et al. Biochemistry 13 3550 1974, Beilstein 22/14 V 116.]

(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Suppliers

Global( 82)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
GL Biochem (Shanghai) Ltd.	+86-021-61263370 +86-18901917034		CHINA	3904	58
GL Biochem(Binhai) Ltd.	+86-021-61263370 +8615301650015	wuqiuyan@glschina.com	China	2975	58
Shanxi Xuanran Import and Export Trade Co., Ltd.	+8617735180244	mike_yan@xuanranglobal.com	CHINA	4017	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19908	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52924	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58
DONBOO AMINO ACID COMPANY	+8613063595538	donboo@donboo.com	China	9363	58

Supplier	Advantage
Jinan Carbotang Biotech Co.,Ltd.	58
Alchem Pharmtech,Inc.	58
GL Biochem (Shanghai) Ltd.	58
GL Biochem(Binhai) Ltd.	58
Shanxi Xuanran Import and Export Trade Co., Ltd.	58
Hefei Hirisun Pharmatech Co., Ltd	58
Nextpeptide Inc	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
DONBOO AMINO ACID COMPANY	58

16626-02-1((S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID)Related Search:

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1of4

5-FLUORO-L-TRYPTOPHAN 5-FLUORO-L-TRYPTOPHAN MONOHYDRATE H-5-FLUORO-TRP-OH H2O L-5-FLUOROTRYPTOPHAN (S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID 5-Fluoro-tryptophan monohydrate H-L-Trp(5-F)-OH*H2O L-5-fluorotryptophan monohydrate (S)-5-Fluoro-α-amino-1H-indole-3-propionic acid (S)-α-Amino-5-fluoro-1H-indole-3-propionic acid (S)-2-AMino-3-(5-fluoro-1H-indol-3-yl)propanoic acid L-Tryptophan, 5-fluoro- (2S)-2-amino-3-(5-fluoro-1H-indol-3-yl)propanoic acid 5-Fluoro-L-tryptophan >=98.0% (HPLC) Tryptophan Impurity 54 5-fluoro-L-tryptophans L-Trp(5-F)-OH 16626-02-1 C11H11FN2O2H2O BioChemical Biochemicals and Reagents Enzyme Inhibitors Enzyme Inhibitors by Type Enzymes, Inhibitors, and Substrates Substrate Analogs Unnatural Amino Acid Derivatives Tryptophan Derivatives F Enzyme Inhibitors by Type Alphabetic Substrate AnalogsPeptide Synthesis FA - FLEnzyme Inhibitors Indoles and derivatives