(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID
- CAS No.
- 16626-02-1
- Chemical Name:
- (S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID
- Synonyms
- L-Trp(5-F)-OH;H-L-Trp(5-F)-OH*H2O;L-5-FLUOROTRYPTOPHAN;5-FLUORO-L-TRYPTOPHAN;H-5-FLUORO-TRP-OH H2O;Tryptophan Impurity 54;5-fluoro-L-tryptophans;L-Tryptophan, 5-fluoro-;5-Fluoro-tryptophan monohydrate;L-5-fluorotryptophan monohydrate
- CBNumber:
- CB1274150
- Molecular Formula:
- C11H11FN2O2
- Molecular Weight:
- 222.22
- MDL Number:
- MFCD00066470
- MOL File:
- 16626-02-1.mol
- MSDS File:
- SDS
Melting point | 238-239 °C |
---|---|
Boiling point | 450.7±45.0 °C(Predicted) |
Density | 1.442±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
form | powder |
pka | 2.21±0.10(Predicted) |
color | white |
BRN | 5052680 |
FDA UNII | 17H03VO4KZ |
UNSPSC Code | 12352209 |
NACRES | NA.77 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
Safety Statements | 22-24/25 |
WGK Germany | 3 |
F | 10 |
HS Code | 2933998090 |
(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID price More Price(20)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 47568 | 5-Fluoro-L-tryptophan ≥98.0% (HPLC) | 16626-02-1 | 25mg | $186 | 2024-03-01 | Buy |
Apolloscientific | PC530031 | 5-Fluoro-L-tryptophan 97% | 16626-02-1 | 1g | $600 | 2021-12-16 | Buy |
Activate Scientific | AS87334 | 5-Fluoro-L-tryptophan 95+% ee | 16626-02-1 | 5G | $1349 | 2021-12-16 | Buy |
AK Scientific | 8456AA | (S)-2-Amino-3-(5-fluoro-1H-indol-3-yl)propanoicacid | 16626-02-1 | 5g | $2650 | 2021-12-16 | Buy |
Activate Scientific | AS87334 | 5-Fluoro-L-tryptophan 95+% ee | 16626-02-1 | 1g | $491 | 2021-12-16 | Buy |
(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Chemical Properties,Uses,Production
Uses
Exogenous 5-fluoro-Trp is incorporated into proteins in normal protein synthesis. Since 19F is a useful reporter group, this provides a method for studying enzyme mechanisms by NMR.
Biochem/physiol Actions
5-Fluoro-Trp is nonspecifically cytotoxic. It is believed this is due to malfunctioning enzymes that have had replacements of Trp residues by 5-fluoro-Trp. However, at least one case is known where 5-fluoro-Trp substitution leads to significantly greater catalytic activity.
Purification Methods
Recrystallise it from EtOH, aqueous EtOH or AcOH. Also purify it by passage through a Dowex AG1x2 (acetate form) column and recrystallise the L-enantiomer (from enzymic enrichment) from H2O/EtOH, m 158-163o(dec), [] D -8.3o (c 2.5, N NaOH). [Coy et al. Biochemistry 13 3550 1974, Beilstein 22/14 V 116.]
(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
GL Biochem (Shanghai) Ltd. | +86-021-61263370 +86-18901917034 | CHINA | 3904 | 58 | |
GL Biochem(Binhai) Ltd. | +86-021-61263370 +8615301650015 | wuqiuyan@glschina.com | China | 2975 | 58 |
Shanxi Xuanran Import and Export Trade Co., Ltd. | +8617735180244 | mike_yan@xuanranglobal.com | CHINA | 4017 | 58 |
Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52924 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
DONBOO AMINO ACID COMPANY | +8613063595538 | donboo@donboo.com | China | 9363 | 58 |
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