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Isopropyl acetoacetate

Isopropyl acetoacetate structure

CAS No.: 542-08-5

Chemical Name:: Isopropyl acetoacetate

Synonyms: IPAA;Isopropylacetoactetate;ACIP;Isopropylacetoacetat;Isopropyl acetoaceta;ISOPROPYL ACETOACETATE;Isopropyl3-oxobutyrate;Isopropyl3-oxobutanoate;IsopropylAcetoacetate>Isopropylacetoacetate,98%

CBNumber:: CB1293982

Molecular Formula:: C7H12O3

Molecular Weight:: 144.17

MDL Number:: MFCD00043933

MOL File:: 542-08-5.mol

Last updated:2025-03-14 08:59:19

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Isopropyl acetoacetate Properties

Melting point	-27°C
Boiling point	95 °C52 hPa(lit.)
Density	0.989 g/mL at 20 °C(lit.)
refractive index	n20/D 1.418
Flash point	73°C
solubility	Chloroform, Ethyl Acetate, Methanol, Toluene,
form	Colourless Liquid
pka	11.67±0.46(Predicted)
color	Colorless to Almost colorless
Water Solubility	Slightly miscible with water.
Merck	14,5206
BRN	1757046
InChIKey	GVIIRWAJDFKJMJ-UHFFFAOYSA-N
LogP	1.060 (est)
CAS DataBase Reference	542-08-5(CAS DataBase Reference)
FDA UNII	38GTB2C6XC
EPA Substance Registry System	Butanoic acid, 3-oxo-, 1-methylethyl ester (542-08-5)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H227-H319-H335

Precautionary statements

P210e-P261-P280a-P305+P351+P338-P405-P501a

Hazard Codes

Risk Statements

Safety Statements

26-36-24/25

WGK Germany

TSCA

Yes

HS Code

29183000

NFPA 704

	2
2		0

Isopropyl acetoacetate price More Price(16)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	689092	Isopropyl acetoacetate Lonza quality, ≥99.0% (GC)	542-08-5	1kg	$151	2024-03-01	Buy
Sigma-Aldrich	689092	Isopropyl acetoacetate Lonza quality, ≥99.0% (GC)	542-08-5	25kg	$2510	2024-03-01	Buy
TCI Chemical	I0826	Isopropyl Acetoacetate >97.0%(GC)	542-08-5	25g	$38	2024-03-01	Buy
TCI Chemical	I0826	Isopropyl Acetoacetate >97.0%(GC)	542-08-5	500g	$469	2024-03-01	Buy
Alfa Aesar	A11907	Isopropyl acetoacetate 98%	542-08-5	50g	$37	2023-06-20	Buy

Product number	Packaging	Price	Buy
689092	1kg	$151	Buy
689092	25kg	$2510	Buy
I0826	25g	$38	Buy
I0826	500g	$469	Buy
A11907	50g	$37	Buy

Isopropyl acetoacetate Chemical Properties,Uses,Production

Chemical Properties

Colourless Liquid

Uses

Isopropyl acetoacetate is used as an intermediate for the manufacturing of agrochemicals and pharmaceutical products such as isradipine.

Uses

Isopropyl acetoacetate (IPAA) is used as intermediate for chemical synthesis. Product Data Sheet

Application

Isopropyl acetoacetate can be used as a reactant to synthesize:
Isopropyl 2-acetyl-3-phenyl-2-propenoate via Knoevenagel reaction in the presence of Ti(O-i-Pr)4.
Substituted 1,4-dihydropyridines by reacting with cinnamaldehydes and primary amines.
5-Isopropoxycarbonyl-6-methyl-4-phenyl-3,4-dihydropyrimidin-2(1H)-thione via Biginelli reaction with benzaldehyde and thiourea.

Synthesis Reference(s)

The Journal of Organic Chemistry, 26, p. 225, 1961 DOI: 10.1021/jo01060a055

Isopropyl acetoacetate synthesis

Synthesis of Isopropyl acetoacetate from Acetyl ketene and Isopropyl alcohol

Isopropyl acetoacetate Preparation Products And Raw materials

Raw materials

Preparation Products

Nimodipine Isradipine Isopropyl 3-aminocrotonate PROPETAMPHOS (5E,9E)-6,10,14-Trimethylpentadeca-5,9,13-trien-2-one

Azelnidipine

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Isopropyl acetoacetate Suppliers

Global( 316)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615531157085	abby@chuanghaibio.com	China	8808	58
Hebei Mujin Biotechnology Co.,Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12809	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5868	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	973	58
Anhuyan (Hainan) Biotechnology Co., LTD	+8618163349544	mollylucking@foxmail.com	China	2764	58
Wuhan Fortuna Chemical Co.,Ltd	+8618007136271	hk@fortunachem.com	China	5992	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29730	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21628	55
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418679 +8618949832763	info@tnjchem.com	China	2986	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29858	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Mujin Biotechnology Co.,Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Anhui Ruihan Technology Co., Ltd	58
Anhuyan (Hainan) Biotechnology Co., LTD	58
Wuhan Fortuna Chemical Co.,Ltd	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Hefei TNJ Chemical Industry Co.,Ltd.	55
career henan chemical co	58

View Lastest Price from Isopropyl acetoacetate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-04-24	Isopropyl acetoacetate 542-08-5	US $0.00-0.00 / KG	1KG	99%	20TONS	Wuhan Fortuna Chemical Co.,Ltd
2025-04-23	Isopropyl acetoacetate 542-08-5	US $8.90 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-04-22	Isopropyl acetoacetate 542-08-5	US $0.00 / G/KG	1G/KG	99%	100MT	Anhuyan (Hainan) Biotechnology Co., LTD

Isopropyl acetoacetate
542-08-5
US $0.00-0.00 / KG
99%
Wuhan Fortuna Chemical Co.,Ltd

Isopropyl acetoacetate
542-08-5
US $8.90 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

Isopropyl acetoacetate
542-08-5
US $0.00 / G/KG
99%
Anhuyan (Hainan) Biotechnology Co., LTD

542-08-5(Isopropyl acetoacetate)Related Search:

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1,3,5,2,4,6-triazatriphosphorine, 2-ethoxy-2,4,4,6,6-pentafluoro-2,2,4,4,6,6-hexahydro- Ethyl 2-(ethoxymethylene)-4,4,4-trifluoroacetoacetate Ethyl acetohydroxamate

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3-oxo-butanoicaci1-methylethylester 3-Oxobutansαure-1-methylethylester 3-Oxo-butyricacidisopropylester Acetoaceticacid,isopropylester acetoaceticacidisopropylester Butanoicacid,3-oxo-,1-methylethylester Isopropyl3-oxobutanoate Isopropyl3-oxobutyrate ISOPROPYL ACETOACETATE ACIP Isopropyl acetoacetate(IPAA) ISOPROPYL ACETOACETATE, WACKER QUALITY Isopropylacetoacetate,98% Isopropylacetoacetat 3-oxo-butanoic acid 1-methylethyl ester 1-methyl-3-oxo-butanoic acid ethyl ester 3-Oxobutanoic acid isopropyl ester 3-ketobutyric acid isopropyl ester Isopropyl acetoaceta Acetoacetic Acid Isopropyl Ester Isopropyl 3-Oxobutyrate 3-Oxobutyric Acid Isopropyl Ester 3-oxobutanoic acid propan-2-yl ester IsopropylAcetoacetate> TIANFU-CHEM - Isopropyl acetoacetate IPAA Isopropylacetoactetate Isopropyl Acetoacetate, ≥ 97.0% 542-08-5 524-08-5 CH3COCH2COOCHCH32 Esters Building Blocks C6 to C7 Carbonyl Compounds Organic Building Blocks Miscellaneous Reagents C6 to C7 Carbonyl Compounds Esters bc0001