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(S)-tert-butyl (2-(2-carbamoyl-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate

(S)-tert-butyl (2-(2-carbamoyl-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate structure

CAS No.: 1448440-48-9

Chemical Name:: (S)-tert-butyl (2-(2-carbamoyl-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate

Synonyms: (S)-1-[2-(Boc-amino)acetyl]-4,4-difluoropyrrolidine-2-carboxamide;N-[(1,1-Dimethylethoxy)carbonyl]glycyl-4,4-difluoro-L-prolinamide;L-Prolinamide, N-[(1,1-dimethylethoxy)carbonyl]glycyl-4,4-difluoro-;(S)-tert-butyl (2-(2-carbamoyl-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate

CBNumber:: CB13052177

Molecular Formula:: C12H19F2N3O4

Molecular Weight:: 307.29

MDL Number:: MFCD29049849

MOL File:: 1448440-48-9.mol

Last updated:2023-05-15 10:43:24

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(S)-tert-butyl (2-(2-carbamoyl-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate Properties

Boiling point	524.1±50.0 °C(Predicted)
Density	1.30±0.1 g/cm3(Predicted)
pka	11.55±0.46(Predicted)

(S)-tert-butyl (2-(2-carbamoyl-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Matrix Scientific	153691	(S)-tert-Butyl (2-(2-carbamoyl-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate 95%	1448440-48-9	250mg	$1847	2021-12-16	Buy
AK Scientific	2081EB	Tert-butylN-[2-(2-carbamoyl-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl]carbamate	1448440-48-9	5g	$2557	2021-12-16	Buy

Product number	Packaging	Price	Buy
153691	250mg	$1847	Buy
2081EB	5g	$2557	Buy

(S)-tert-butyl (2-(2-carbamoyl-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate Chemical Properties,Uses,Production

Uses

N-[(1,1-Dimethylethoxy)carbonyl]glycyl-4,4-difluoro-L-prolinamide is an intermediate in the synthesis of (S)-N-(2-(2-Cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide (UAMC1110) (S687910) which is a useful research chemical and a fibroblast activation protein inhibitor displaying low nanomolar inhibitory potency and high selectivity against related dipeptidyl peptidases.

(S)-tert-butyl (2-(2-carbamoyl-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate Preparation Products And Raw materials

Raw materials

Preparation Products

(S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide

(S)-tert-butyl (2-(2-carbamoyl-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate Suppliers

Global( 7)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19994	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58
Wuxi KaideRui Pharmaceutical Technology Co., Ltd	19906241957	1557216087@qq.com	China	1762	55
Accela ChemBio Co.,Ltd.	021-50795510 4000665055	sales@accelachem.com	China	11728	58
Shanghai Maclean Biochemical Technology Co., LTD	021-50706066 15221275939	shenlinxing@macklin.cn	China	29803	58

Supplier	Advantage
Accela ChemBio Inc.	58
Labnetwork lnc.	58
Amadis Chemical Company Limited	58
Wuxi KaideRui Pharmaceutical Technology Co., Ltd	55
Accela ChemBio Co.,Ltd.	58
Shanghai Maclean Biochemical Technology Co., LTD	58

(S)-tert-butyl (2-(2-carbamoyl-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate (S)-1-[2-(Boc-amino)acetyl]-4,4-difluoropyrrolidine-2-carboxamide L-Prolinamide, N-[(1,1-dimethylethoxy)carbonyl]glycyl-4,4-difluoro- N-[(1,1-Dimethylethoxy)carbonyl]glycyl-4,4-difluoro-L-prolinamide 1448440-48-9 C12H19F2N3O4