Azadirachtin | 11141-17-6

Azadirachtin Properties

Melting point	159°C
alpha	D -53° (c = 0.5 in CHCl3)
Boiling point	792.4±60.0 °C(Predicted)
Density	1.51
storage temp.	−20°C
solubility	DMSO (Sparingly), Methanol (Slightly)
pka	9.78±0.70(Predicted)
form	Solid
color	White to Pale Yellow
Merck	13,896
Stability	Light Sensitive
InChIKey	TWGPOIQWWGNBKW-POEZYEDVSA-N
LogP	1.090
CAS DataBase Reference	11141-17-6
FDA UNII	O4U1SAF85H
EPA Substance Registry System	Azadirachtin A (11141-17-6)
Pesticides Freedom of Information Act (FOIA)	Azadirachtin

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS09
Signal word	Warning
Hazard statements	H317-H410
Precautionary statements	P261-P272-P273-P280-P302+P352-P333+P313
Risk Statements	22
Safety Statements	22-45
RIDADR	3077
WGK Germany	3
HazardClass	9
PackingGroup	III
HS Code	13021920
Hazardous Substances Data	11141-17-6(Hazardous Substances Data)

Azadirachtin price More Price(13)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PHL89574	Azadirachtin phyproof? Reference Substance	11141-17-6	5MG	$459	2024-03-01	Buy
Sigma-Aldrich	A7430	Azadirachtin ~95%	11141-17-6	0.5mg	$140	2024-03-01	Buy
Cayman Chemical	21893	Azadirachtin ≥95%	11141-17-6	1mg	$57	2024-03-01	Buy
Cayman Chemical	21893	Azadirachtin ≥95%	11141-17-6	5mg	$220	2024-03-01	Buy
Cayman Chemical	21893	Azadirachtin ≥95%	11141-17-6	10mg	$330	2024-03-01	Buy

Product number	Packaging	Price	Buy
PHL89574	5MG	$459	Buy
A7430	0.5mg	$140	Buy
21893	1mg	$57	Buy
21893	5mg	$220	Buy
21893	10mg	$330	Buy

Azadirachtin Chemical Properties,Uses,Production

Description

Kernel extracts from the Indian neem tree (Azadirachta indica) have insecticidal and insect-repellent properties. The key active ingredient is azadirachtin, a nortriterpenoid that exhibits insect growth regulator effects but no adulticidal activity.

Chemical Properties

Off-white, yellowish powder or dark brown emulsifiable concentrate.

Uses

Azadirachtin is a tetranortriterpinoid isolated from the seeds of the neem tree. Highly active insect feeding deterrent and growth regulator.It is used experimentally as insect control agent.

Uses

Azadiractin is extracted from the neem tree (Azadirachta indica). It is the principal active ingredient of extracts of neem. Neem extracts and pure azadirachtin are used to control whitefly, leaf miners and other pests including pear psylla.

Definition

ChEBI: A member of the family of azadirachtins that is isolated from the neem tree (Azadirachta indica).

Agricultural Uses

Insecticides, Nematicide: Azadirachtin is an extract of fruit from the Neem tree, which is largely grown in India. It is used as a commercial insect growth regulator that controls the metamorphosis process as the insect passes from the larva stage to the pupa stage. The Neem tree also yields extracts from its bark, leaves and wood that are used in medicine and cosmetics.

Trade name

ALIGN®; AZATIN EC®; AZATIN®-XL PLUS; AZATROL EC®; AMAZIN® ECOZIN® EI- 783®; MARGOSAN-O®; NEEM®; NEEMAZAL®; ORNAZIN® SALANNIN®; SUPERNEEM®; TURPLEX®

Biochem/physiol Actions

Triterpenoid found in need tree seeds, azadiractin suppresses feeding by many insect species and disrupts growth of most insect and other arthropod species, while having very low mammalian toxicity. Promising as a natural pesticide.

Potential Exposure

Biological tetranortriterpinoid insecticide; insect growth regulator. A natural product extracted from seeds of the Neem tree (Azadirachta indica).

Metabolic pathway

The natural insecticide azadirachtin is most stable in mildly acidic solutions between pH 4 and 6 at room temperature and unstable in alkaline and strong acidic conditions. While azadirachtin is relatively stable to heating in the seeds or as a pure solid, it is rapidly destroyed or altered by heating in aqueous solution and methanol. In methanol at 90°C, it is quantitatively converted to 3-acetyl-1-tigloylazadirachtinin.

Shipping

UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.

Degradation

After 90 hours exposure to UV radiation, very little azadirachtin (l)its 3- acetyl derivative and 22,23-dihydroazadirachtin remained intact. However, these compounds retained biological activity, and at least 200 hours irradiation was necessary to reduce the biological activity of 1. It is suggested that the effect of ultraviolet radiation is confined to the tigloyl residue which is common to these three compounds and which may undergo cis-trans isomerisation, rearrangement, etc. without significant effect on the biological activity of the molecule, because reduction or removal of the tigloyl residue causes only limited reduction in biological activity of the parent (Barnby ef al., 1989).
Azadirachtin was hydrolysed readily in several buffers (pH 4.1-8.1) and natural waters (pH 6.2,7.3,8.0 and 8.1) at 35 °C and its disappearance followed pseudo-first-order kinetics (Szeto and Wan, 1996). Rates of disappearance of the parent were faster in basic than in acidic solution (DT₅₀ was 12 hours at pH 8 and 206 hours at pH 6) and the compound is not expected to be persistent in water.

Mode of action

Azadirachtin acts on insect gustatory receptors to inhibit feeding, and also interferes with development by inhibiting synthesis of the neuropeptide that triggers ecdysone release. The molecular targets mediating these effects are not known.

Toxicity evaluation

Azadirachtin is practically non-toxic to mammals, birds and plants. It is moderately toxic to aquatic invertebrates, but exposure is negligible due to low application rates and rapid degradation. Since it is only active by ingestion of treated foliage, exposure of non-target insects and honeybees is minimal.

Incompatibilities

Powder or liquid may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, reducing agents and metals, acid chlorides, alkalis, alkali metals, high heat, including sunlight.

Waste Disposal

Waste product may be disposed of onsite (open dumping may be prohibited) or at an approved waste disposal facility. All federal, state, and local environmental regulations must be observed.

Azadirachtin Preparation Products And Raw materials

Raw materials

Preparation Products

Azadirachtin Suppliers

Global( 216)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Weibang Biotechnology Co., Ltd	+8615531157085	abby@weibangbio.com	China	8810	58
Hebei Mojin Biotechnology Co., Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12835	58
Hebei Mojin Biotechnology Co.,Ltd	+86-15028179902	angelia@hbmojin.com	China	1176	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3619	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29880	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3772	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Xi'an Kono chem co., Ltd.,	029-86107037 13289246953	info@konochemical.com	China	1169	58

Supplier	Advantage
Hebei Weibang Biotechnology Co., Ltd	58
Hebei Mojin Biotechnology Co., Ltd	58
Hebei Mojin Biotechnology Co.,Ltd	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Chengdu Biopurify Phytochemicals Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58
Xi'an Kono chem co., Ltd.,	58

View Lastest Price from Azadirachtin manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-19	Azadirachtin 11141-17-6	US $98.00-368.00 / mg		98.63%	10g	TargetMol Chemicals Inc.
2024-11-05	Azadirachtin 11141-17-6	US $10.00 / KG	1KG	99%	10 mt	Hebei Weibang Biotechnology Co., Ltd
2024-08-14	Azadirachta Indica Extract 11141-17-6	US $0.00 / kg	1kg	99%	50000KG/month	Hebei Mojin Biotechnology Co.,Ltd

Azadirachtin
11141-17-6
US $98.00-368.00 / mg
98.63%
TargetMol Chemicals Inc.

Azadirachtin
11141-17-6
US $10.00 / KG
99%
Hebei Weibang Biotechnology Co., Ltd

Azadirachta Indica Extract
11141-17-6
US $0.00 / kg
99%
Hebei Mojin Biotechnology Co.,Ltd

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AZATIN AZATIN(R) KAYNEEM 3-TIGLOYL-AZADIRACHTOL AZADIRACHTIN, 10MG, NEAT 1H,7H-Naphtho1,8-bc:4,4a-cdifuran-5,10a(8H)-dicarboxylic acid, 10-(acetyloxy)octahydro-3,5-dihydroxy-4-methyl-8-(2E)-2-methyl-1-oxo-2-butenyloxy-4-(1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-methyl-2,7-methanofuro2,3-boxirenoeoxepin-1a(2H) AZADIRACHTIN pure AZADIRACTIN PHEROTECH Azadirachtin 10mg [11141-17-6] Azaditrachtin Nsc368675 AZADIRACHTIN A(P) NEEMOLIN NEEMAZAD NEEMAZAL NEEMIX AZAD AZADIRACCHTIN A AZADIRACHTIN (2aR,3S,4S,4aR,5S,7aS,8S,10R,10aS,10bR)-10-(Acetyloxy)octahydro-3,5-dihydroxy-4-methyl-8-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]-4-[(1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-methyl-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl]-1H,7H-naphtho[1,8-bc:4,4a-c']difuran-5,10a(8H)-dicarboxylic acid 5,10a-dimethyl ester Azatin EC Azatin Magnum Azatin XL Ecozin Gronim NeemAzal F NeemAzal T NeemAzal W Neemazol Neemgold Nimbicidine Nimurin Oikos Oikos 25 plus Oikos 323 Bio Ornazin Safer BioNEEM Suneem Superneem (2aR,3S,4S,4aR,5S,7aS,8S,10R,10aS,10bR)-10-(Acetyloxy)octahydro-3,5-dihydroxy-4-Methyl-8-[[(2E)-2-Methyl-1-oxo-2-buten-1-yl]oxy]-4-[(1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-Methyl-2,7-Methanofuro[2,3-b]oxireno[e]oxepin-1a(2 1H,7H-Naphtho[1,8-bc:4,4a-c']difuran-5,10a(8H)-dicarboxylicacid,10-(acetyloxy)octahydro-3,5-dihydroxy-4-Methyl-8-[[(2E)-2-Methyl-1-oxo-2-buten-1-yl]oxy]-4-[(1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-Methyl-2,7-Methanofuro[2,3-b]oxireno[e] Azadirachtin Solution, 100ppm Azadirachtin(Technical) Azadirachtin @100 μg/mL in Methanol 1H,7H-Naphtho[1,8-bc:4,4a-c']difuran-5,10a(8H)-dicarboxylic acid, 10-(acetyloxy)octahydro-3,5-dihydroxy-4-methyl-8-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]-4-[(1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-methyl-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl]-, 5,10a-dimethyl ester, (... AZADIRACHTIN B AZADIRACHTIN A Azadirachtin 100 μg/mL in Acetonitrile Cypermethrin Impurity 8 Azadirachtin in Methanol Azadirachtin A 100 μg/ml Acetonitrile Azadirachtin-RM 11141-17-6 1141-17-6 C30H36O9 C35H44O16 Analytical Standards