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ChemicalBook >> CAS DataBase List >>N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide

N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide

N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide Structure
N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide structure
CAS No.
1776112-90-3
Chemical Name:
N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide
Synonyms
CPI-637;PF 6747775;PF-06747775;MAVELERTINIB;Mavelertinib( PF-06747775);N-[(3R,4R)-4-fluoro-1-[6-[(3-methoxy-1-methylpyrazol-4-yl)amino]-9-methylpurin-2-yl]pyrrolidin-3-yl]prop-2-enamide;N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide;2-Propenamide, N-[(3R,4R)-4-fluoro-1-[6-[(3-methoxy-1-methyl-1H-pyrazol-4-yl)amino]-9-methyl-9H-purin-2-yl]-3-pyrrolidinyl]-
CBNumber:
CB13133470
Molecular Formula:
C18H22FN9O2
Molecular Weight:
415.42
MDL Number:
MFCD29079007
MOL File:
1776112-90-3.mol
Last updated:2023-05-04 15:14:25
Request For Quotation

N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide Properties

Density 1.52±0.1 g/cm3(Predicted)
storage temp. room temp
form powder
pka 12.93±0.40(Predicted)
color white to beige
FDA UNII YXX2180047

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Warning
Hazard statements  H373
Precautionary statements  P260-P314-P501

N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PZ0302 PF-06747775 ≥98% (HPLC) 1776112-90-3 5mg $47.2 2024-03-01 Buy
TRC P218315 PF06747775 1776112-90-3 0.5mg $160 2021-12-16 Buy
TRC P218315 PF06747775 1776112-90-3 10mg $2600 2021-12-16 Buy
TRC P218315 PF06747775 1776112-90-3 25mg $6275 2021-12-16 Buy
ChemScene CS-0012907 Mavelertinib ≥99.0% 1776112-90-3 1mg $200 2021-12-16 Buy
Product number Packaging Price Buy
PZ0302 5mg $47.2 Buy
P218315 0.5mg $160 Buy
P218315 10mg $2600 Buy
P218315 25mg $6275 Buy
CS-0012907 1mg $200 Buy

N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide Chemical Properties,Uses,Production

Uses

PF 06747775 is an orally available inhibitor of the epidermall growth factor receptor (EGFR) mutant form T790M showing antineoplastic activity.

N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide Suppliers

Global( 37)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
NINGBOBENKANGJS PHARMTECHCO., LTD 		+8615990591583 15990591583 CHINA 2029 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139 orders@jknbiochem.com China 5225 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4309 55
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994 2853530910@QQ.com China 8014 62
Jinan elephant international trading co., LTD 13006575422@163.com China 6357 58
Zhongshan Geometric Biological Technology Co., Ltd. +86-13168912896 China 253 58
Kaixin Chemical (Hong Kong) Limited 010-88886666-01 13112345678 loyson@tcypharm.com China 595 55
Shanghai Biopharmaleader Co., Ltd. +86 18721201413 sales@biopharmaleader.com China 1720 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
NINGBOBENKANGJS PHARMTECHCO., LTD 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		58
Shanghai Lollane Biological Technology Co.,Ltd. 55
ShangHai Biochempartner Co.,Ltd 62
Jinan elephant international trading co., LTD 58
Zhongshan Geometric Biological Technology Co., Ltd. 58
Kaixin Chemical (Hong Kong) Limited 55
Shanghai Biopharmaleader Co., Ltd. 58
N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide PF-06747775 CPI-637 MAVELERTINIB N-[(3R,4R)-4-fluoro-1-[6-[(3-methoxy-1-methylpyrazol-4-yl)amino]-9-methylpurin-2-yl]pyrrolidin-3-yl]prop-2-enamide PF 6747775 2-Propenamide, N-[(3R,4R)-4-fluoro-1-[6-[(3-methoxy-1-methyl-1H-pyrazol-4-yl)amino]-9-methyl-9H-purin-2-yl]-3-pyrrolidinyl]- Mavelertinib( PF-06747775) 1776112-90-3 C18H22FN9O2