ChemicalBook >> CAS DataBase List >>Tavilermide
Tavilermide
- CAS No.
- 263251-78-1
- Chemical Name:
- Tavilermide
- Synonyms
- MIM-D3;Tavilermide;Glycine, N-(2-hydroxy-5-nitrobenzoyl)-L-α-glutamyl-L-lysyl-L-homoseryl-, cyclic (1→3)-ether;3-((4S,7S,10S)-7-(4-aminobutyl)-4-((carboxymethyl)carbamoyl)-14-nitro-6,9,12-trioxo-3,4,5,6,7,8,9,10,11,12-decahydro-2H-benzo[b][1,5,8,11]oxatriazacyclotetradecin-10-yl)propanoic acid;3-((4S,7S,10S)-7-(4-aminobutyl)-4-((carboxymethyl)carbamoyl)-14-nitro-6,9,12-trioxo-3,4,5,6,7,8,9,10,11,12-decahydro-2H-benzo[b][1,5,8,11]oxatriazacyclotetradecin-10-yl)propanoic acid(WXG02263)
- CBNumber:
- CB13143877
- Molecular Formula:
- C24H32N6O11
- Molecular Weight:
- 580.55
- MDL Number:
- MFCD30533429
- MOL File:
- 263251-78-1.mol
Last updated:2024-07-02 08:55:00
| Boiling point | 1122.4±65.0 °C(Predicted) |
|---|---|
| Density | 1.341±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| form | Solid |
| pka | 3.59±0.10(Predicted) |
| color | White to off-white |
| Water Solubility | Water : 5 mg/mL (8.61 mM; adjust pH to 3-4 with HCl) |
| FDA UNII | NMG938VJ6T |
Tavilermide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-7495 | Tavilermide 99.62% | 263251-78-1 | 1mg | $180 | 2021-12-16 | Buy |
| ChemScene | CS-7495 | Tavilermide 99.62% | 263251-78-1 | 5mg | $540 | 2021-12-16 | Buy |
| ChemScene | CS-7495 | Tavilermide 99.62% | 263251-78-1 | 10mg | $900 | 2021-12-16 | Buy |
| ChemScene | CS-7495 | Tavilermide 99.62% | 263251-78-1 | 50mg | $2700 | 2021-12-16 | Buy |
| ChemScene | CS-7495 | Tavilermide 99.62% | 263251-78-1 | 100mg | $3960 | 2021-12-16 | Buy |
Tavilermide Chemical Properties,Uses,Production
Biological Activity
Tavilermide is a selective TrkA partial agonist.
in vitro
Tavilermide (MIM-D3) is a tyrosine kinase TrkA receptor agonist, which can be used to treat dry eye. Tavilermide is a proteolytically stable, cyclic peptidomimetic that has been shown to be a partial TrkA receptor agonist. Tavilermide demonstrates activities similar to NGF (but does not bind to the p75NTR receptor) and can potentiate the effects of suboptimal concentrations of NGF.
target
TrkA
Tavilermide Preparation Products And Raw materials
Raw materials
Preparation Products
Tavilermide Suppliers
Global( 15)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19994 | 58 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7892 | 56 |
| Shanghai Biopharmaleader Co., Ltd. | +86 18721201413 | sales@biopharmaleader.com | China | 1720 | 58 |
| Shenzhen Regent Biochemical Technology Co., Ltd. | 0755-0755-85201366 18938635012 | sales@regentsciences.com | China | 9299 | 58 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 | eric@peptidego.com | China | 6526 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 29778 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
| Hangzhou Sinoda Pharmaceutical Technology Co. LTD | 0571-87213919 17306812703 | 3007955328@qq.com | China | 6213 | 58 |
Tavilermide
3-((4S,7S,10S)-7-(4-aminobutyl)-4-((carboxymethyl)carbamoyl)-14-nitro-6,9,12-trioxo-3,4,5,6,7,8,9,10,11,12-decahydro-2H-benzo[b][1,5,8,11]oxatriazacyclotetradecin-10-yl)propanoic acid(WXG02263)
Glycine, N-(2-hydroxy-5-nitrobenzoyl)-L-α-glutamyl-L-lysyl-L-homoseryl-, cyclic (1→3)-ether
3-((4S,7S,10S)-7-(4-aminobutyl)-4-((carboxymethyl)carbamoyl)-14-nitro-6,9,12-trioxo-3,4,5,6,7,8,9,10,11,12-decahydro-2H-benzo[b][1,5,8,11]oxatriazacyclotetradecin-10-yl)propanoic acid
MIM-D3
263251-78-1
C24H32N6O11