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Maresin 2

CAS No.
1639809-46-3
Chemical Name:
Maresin 2
Synonyms
Maresin 2;4,7,9,11,16,19-Docosahexaenoic acid, 13,14-dihydroxy-, (4Z,7Z,9E,11E,13R,14S,16Z,19Z)-
CBNumber:
CB13152671
Molecular Formula:
C22H32O4
Molecular Weight:
360.49
MDL Number:
MOL File:
1639809-46-3.mol
Last updated:2024-07-02 08:55:00

Maresin 2 Properties

Boiling point 559.4±50.0 °C(Predicted)
Density 1.048±0.06 g/cm3(Predicted)
storage temp. Store at -80°C
solubility DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): .05 mg/ml
form Liquid
pka 4.57±0.10(Predicted)
color Colorless to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS02
Signal word  Danger
NFPA 704
3
0 0

Maresin 2 price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 16369 Maresin 2 ≥95% 1639809-46-3 10μg $77 2024-03-01 Buy
Cayman Chemical 16369 Maresin 2 ≥95% 1639809-46-3 25μg $180 2024-03-01 Buy
Cayman Chemical 16369 Maresin 2 ≥95% 1639809-46-3 50μg $340 2024-03-01 Buy
Cayman Chemical 16369 Maresin 2 ≥95% 1639809-46-3 100μg $602 2024-03-01 Buy
Product number Packaging Price Buy
16369 10μg $77 Buy
16369 25μg $180 Buy
16369 50μg $340 Buy
16369 100μg $602 Buy

Maresin 2 Chemical Properties,Uses,Production

Description

Docosahexaenoic acid (DHA; ) is an ω-3 fatty acid that is abundant in the brain and the retina and is known to be important in early development. Maresin 2 (MaR2) is a 13R,14S-dihydroxy DHA formed by recombinant human macrophage 12-lipoxygenase and soluble epoxide hydrolase co-incubated with DHA. At 1 ng/mouse, MaR2 was shown to reduce neutrophil infiltration by 40% in a mouse model of peritonitis, and at 10 pM, MaR2 can enhance human macrophage phagocytosis of zymosan A by 90%. Analytical and biological comparisons of synthetic MaR2 with endogenously derived MaR2 have confirmed its identity as matching the natural product.

Definition

ChEBI: (13R,14S)-dihydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoic acid is a dihydroxydocosahexaenoic acid that is (4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoic acid in which the two hydroxy substituents are located at the 13R- and 14S-positions. It has a role as a human xenobiotic metabolite, an anti-inflammatory agent and a specialised pro-resolving mediator. It is a dihydroxydocosahexaenoic acid and a secondary allylic alcohol. It is a conjugate acid of a (13R,14S)-dihydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate.

Maresin 2 Preparation Products And Raw materials

Raw materials

Preparation Products

Maresin 2 Suppliers

Global( 17)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8739 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 28091 58
Maresin 2 4,7,9,11,16,19-Docosahexaenoic acid, 13,14-dihydroxy-, (4Z,7Z,9E,11E,13R,14S,16Z,19Z)- 1639809-46-3