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EGF816 (S-enantiomer)

EGF816 (S-enantiomer) Structure
EGF816 (S-enantiomer) structure
CAS No.
1508256-20-9
Chemical Name:
EGF816 (S-enantiomer)
Synonyms
EGF816 (S-enantiomer);Nazartinib S-enantiomer (EGF816);N-[7-chloro-1-[(3S)-1-[(E)-4-(dimethylamino)but-2-enoyl]azepan-3-yl]benzimidazol-2-yl]-2-methylpyridine-4-carboxamide;4-Pyridinecarboxamide, N-[7-chloro-1-[(3S)-1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]hexahydro-1H-azepin-3-yl]-1H-benzimidazol-2-yl]-2-methyl-
CBNumber:
CB13160069
Molecular Formula:
C26H31ClN6O2
Molecular Weight:
495.02
MDL Number:
MFCD30534426
MOL File:
1508256-20-9.mol
Last updated:2024-07-02 08:55:00
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EGF816 (S-enantiomer) Properties

Density 1.28±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 50 mg/mL (101.01 mM); Water: < 0.1 mg/mL (insoluble)
pka 11.38±0.43(Predicted)
form Solid
color White to off-white

EGF816 (S-enantiomer) Chemical Properties,Uses,Production

Description

Nazartinib S-enantiomer (EGF816 S-enantiomer) is the less active S-enantiomer of Nazartinib. Nazartinib (EGF816) is an EGFR inhibitor.

References

[1]. Gerald Lelais, et al. Compounds and compositions for modulating egfr activity. WO 2013184757A1.

EGF816 (S-enantiomer) Preparation Products And Raw materials

Raw materials

Preparation Products

EGF816 (S-enantiomer) Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Musechem +1-800-259-7612 info@musechem.com United States 4662 60
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Absin Bioscience Inc. 021-38015121 15000105423 wulan@absin.cn China 24734 58
InvivoChem 13549236410 sales@invivochem.cn China 6755 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
InvivoChem 		58
Aladdin Scientific 		58
Musechem 60
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Absin Bioscience Inc. 58
InvivoChem 58

1508256-20-9(EGF816 (S-enantiomer))Related Search:

EGF816
EGF816 (S-enantiomer) N-[7-chloro-1-[(3S)-1-[(E)-4-(dimethylamino)but-2-enoyl]azepan-3-yl]benzimidazol-2-yl]-2-methylpyridine-4-carboxamide 4-Pyridinecarboxamide, N-[7-chloro-1-[(3S)-1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]hexahydro-1H-azepin-3-yl]-1H-benzimidazol-2-yl]-2-methyl- Nazartinib S-enantiomer (EGF816) 1508256-20-9 C26H31ClN6O2