ChemicalBook >> CAS DataBase List >>2,4,6,8,12,18,20,22,24,26,38,48,52-Hexacontatridecaenoicacid, 60-amino-15,17,29,33,35,37,41,43,45,47,51,55,57-tridecahydroxy-2,14,16,30-tetramethyl-31-oxo-,(2E,4E,6E,8E,12E,15S,16S,17R,18E,20E,22E,24E,26E,35S,37S,38E,41R,43S,45R,47S,48E,52E,55S,57R)-
2,4,6,8,12,18,20,22,24,26,38,48,52-Hexacontatridecaenoicacid, 60-amino-15,17,29,33,35,37,41,43,45,47,51,55,57-tridecahydroxy-2,14,16,30-tetramethyl-31-oxo-,(2E,4E,6E,8E,12E,15S,16S,17R,18E,20E,22E,24E,26E,35S,37S,38E,41R,43S,45R,47S,48E,52E,55S,57R)-
- CAS No.
- 163596-98-3
- Chemical Name:
- 2,4,6,8,12,18,20,22,24,26,38,48,52-Hexacontatridecaenoicacid, 60-amino-15,17,29,33,35,37,41,43,45,47,51,55,57-tridecahydroxy-2,14,16,30-tetramethyl-31-oxo-,(2E,4E,6E,8E,12E,15S,16S,17R,18E,20E,22E,24E,26E,35S,37S,38E,41R,43S,45R,47S,48E,52E,55S,57R)-
- Synonyms
- Linearmycin A;60-amino-15S,17R,29,33,35S,37S,41R,43S,45R,47S,51,55S,57R-tridecahydroxy-2,14,16S,30-tetramethyl-31-oxo-2E,4E,6E,8E,12E,18E,20E,22E,24E,26E,38E,48E,52E-hexacontatridecaenoic acid;2,4,6,8,12,18,20,22,24,26,38,48,52-Hexacontatridecaenoicacid, 60-amino-15,17,29,33,35,37,41,43,45,47,51,55,57-tridecahydroxy-2,14,16,30-tetramethyl-31-oxo-,(2E,4E,6E,8E,12E,15S,16S,17R,18E,20E,22E,24E,26E,35S,37S,38E,41R,43S,45R,47S,48E,52E,55S,57R)-
- CBNumber:
- CB13197481
- Molecular Formula:
- C64H101NO16
- Molecular Weight:
- 1140.48384
- MDL Number:
- MOL File:
- 163596-98-3.mol
Last updated:2023-05-21 10:59:17
2,4,6,8,12,18,20,22,24,26,38,48,52-Hexacontatridecaenoicacid, 60-amino-15,17,29,33,35,37,41,43,45,47,51,55,57-tridecahydroxy-2,14,16,30-tetramethyl-31-oxo-,(2E,4E,6E,8E,12E,15S,16S,17R,18E,20E,22E,24E,26E,35S,37S,38E,41R,43S,45R,47S,48E,52E,55S,57R)- Properties
| storage temp. | -20°C |
|---|---|
| solubility | DMSO: soluble; Methanol: soluble |
| form | A solid |
2,4,6,8,12,18,20,22,24,26,38,48,52-Hexacontatridecaenoicacid, 60-amino-15,17,29,33,35,37,41,43,45,47,51,55,57-tridecahydroxy-2,14,16,30-tetramethyl-31-oxo-,(2E,4E,6E,8E,12E,15S,16S,17R,18E,20E,22E,24E,26E,35S,37S,38E,41R,43S,45R,47S,48E,52E,55S,57R)- Chemical Properties,Uses,Production
Biological Activity
Linearmycin A is a polyene antibiotic that has been found in Streptomyces.1 It is active against the bacteria S. aureus and E. coli (MICs = 3.1 and 1.6 μg/disc, respectively), the fungi S. cerevisiae and C. albicans (MICs = 0.1 and 1.6 μg/disc, respectively), and the plant pathogenic fungus A. niger in disc assays (MIC = 0.2 μg/disc). Linearmycin A induces lysis and degradation of B. subtilis as a component of Streptomyces Mg1 extract.2
References
1.Sakuda, S., Guce-Bigol, U., Itoh, M., et al.Novel linear polyene antibiotics: LinearmycinsJ. Chem. Soc., Perkin Trans. 1182315-2319(1996) 2.Stubbendieck, R.M., and Straight, P.D.Escape from lethal bacterial competition through coupled activation of antibiotic resistance and a mobilized subpopulationPLoS Genet.11(12)e1005722(2015)
2,4,6,8,12,18,20,22,24,26,38,48,52-Hexacontatridecaenoicacid, 60-amino-15,17,29,33,35,37,41,43,45,47,51,55,57-tridecahydroxy-2,14,16,30-tetramethyl-31-oxo-,(2E,4E,6E,8E,12E,15S,16S,17R,18E,20E,22E,24E,26E,35S,37S,38E,41R,43S,45R,47S,48E,52E,55S,57R)- Preparation Products And Raw materials
Raw materials
Preparation Products
2,4,6,8,12,18,20,22,24,26,38,48,52-Hexacontatridecaenoicacid, 60-amino-15,17,29,33,35,37,41,43,45,47,51,55,57-tridecahydroxy-2,14,16,30-tetramethyl-31-oxo-,(2E,4E,6E,8E,12E,15S,16S,17R,18E,20E,22E,24E,26E,35S,37S,38E,41R,43S,45R,47S,48E,52E,55S,57R)- Suppliers
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| Supplier | Tel | Country | ProdList | Advantage | |
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| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
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| BOC Sciences | 65 |
| ChemeGen 中国 | 58 |
| Beijing Biocreative Technology Co., Ltd. | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 58 |
2,4,6,8,12,18,20,22,24,26,38,48,52-Hexacontatridecaenoicacid, 60-amino-15,17,29,33,35,37,41,43,45,47,51,55,57-tridecahydroxy-2,14,16,30-tetramethyl-31-oxo-,(2E,4E,6E,8E,12E,15S,16S,17R,18E,20E,22E,24E,26E,35S,37S,38E,41R,43S,45R,47S,48E,52E,55S,57R)-
Linearmycin A
60-amino-15S,17R,29,33,35S,37S,41R,43S,45R,47S,51,55S,57R-tridecahydroxy-2,14,16S,30-tetramethyl-31-oxo-2E,4E,6E,8E,12E,18E,20E,22E,24E,26E,38E,48E,52E-hexacontatridecaenoic acid
163596-98-3
C64H101NO16