MELOXICAM-D3
- CAS No.
- 942047-63-4
- Chemical Name:
- MELOXICAM-D3
- Synonyms
- Mobic-d3;Metacam-d3;Parocin-d3;Movatec-d3;Movalis-d3;Mobicox-d3;MELOXICAM-D3;Meloxicam D4;[2H3]-Meloxicam;Meloxicam-d3
- CBNumber:
- CB1327322
- Molecular Formula:
- C14H13N3O4S2
- Molecular Weight:
- 351.4
- MDL Number:
- MFCD08063461
- MOL File:
- Mol file
| Melting point | 249-251°C |
|---|---|
| storage temp. | -20°C Freezer |
| solubility | DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml |
| form | Solid |
| color | Light yellow to yellow |
| CAS DataBase Reference | 942047-63-4 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P264-P270-P301+P310-P405-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
MELOXICAM-D3 price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 34109 | Meloxicam-d3 VETRANAL?, analytical standard | 942047-63-4 | 50mg | $856 | 2022-05-15 | Buy |
| Cayman Chemical | 25508 | Meloxicam-d3 ≥99% deuterated forms (d1-d3) | 942047-63-4 | 500μg | $175 | 2024-03-01 | Buy |
| Cayman Chemical | 25508 | Meloxicam-d3 ≥99% deuterated forms (d1-d3) | 942047-63-4 | 1mg | $330 | 2024-03-01 | Buy |
| TRC | M216102 | Meloxicam-d3 | 942047-63-4 | 1mg | $175 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | RDL0006923 | MELOXICAM-D3 95.00% | 942047-63-4 | 10MG | $1871.1 | 2021-12-16 | Buy |
MELOXICAM-D3 Chemical Properties,Uses,Production
Description
Meloxicam-d3 is intended for use as an internal standard for the quantification of meloxicam by GC- or LC-MS. Meloxicam is a selective inhibitor of COX-2 (IC50s = 11.8 and 143 μM for COX-2 and COX-1, respectively, in an enzyme activity assay) and a non-steroidal anti-inflammatory drug (NSAID). Meloxicam (0.03%) reduces croton oil-induced increases in TNF-α and IL-1β mRNA levels and increases IL-10 mRNA levels in cornea in a rabbit model of acute ocular inflammation. It inhibits pleural plasma exudation in a carrageenan-induced rat model of pleurisy when administered at a dose of 3 mg/kg.In a canine model of unilateral osteoarthritis of the right stifle joint, meloxicam reduces prostaglandin E2 (PGE2) levels in plasma and right stifle joint synovial fluid when administered at a dose of 0.2 mg/kg. Formulations containing meloxicam have been used in the treatment of osteoarthritis and rheumatoid arthritis.
Chemical Properties
Yellow Solid
Uses
MELOXICAM-D3 is a preferential cyclooxygenase (COX-2) inhibitor,it is used as an anti-inflammatory.
References
1. Ogino, K., Hatanaka, K., Kawamura, M., et al. Evaluation of pharmacological profile of meloxicam as an anti-inflammatory agent, with particular reference to its relative selectivity for cyclooxygenase-2 over cyclooxygenase-1. Pharmacology 55, 44-53 (1997).
2. Cruz, R., Quintana-Hau, J.D., González, J.R., et al. Effects of an ophthalmic formulation of meloxicam on COX-2 expression, PGE2 release, and cytokine expression in a model of acute ocular inflammation. Br. J. Ophthalmol. 92, 120-125 (2008).
3. Jones, C.J., Streppa, H.K., Harmon, B.G., et al. In vivo effects of meloxicam and aspirin on blood, gasteric mucosal, and synovial fluid prosanoid synthesis in dogs. Am. J. Vet. Res. 63, 1527-1531 (2002).
MELOXICAM-D3 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SIMSON PHARMA LIMITED | +91-8291074273 | k.das@simsonpharma.com | India | 228 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 | |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32321 | 50 |
| Clearsynth Labs Limited | +91-22-26355700 | info@clearsynth.com | India | 9679 | 58 |
| Cato Research Chemicals Inc. | 020-81960175 | min.he@cato-chem.com | China | 1955 | 55 |
| Alta Scientific Co., Ltd. | 022-6537-8550 15522853686 | sales@altasci.com.cn | China | 4511 | 55 |
| Artis Biotech Co. Ltd. | 0575-18780151478 18582380095 | sales@artisbio.com | China | 2966 | 58 |
| Chengdu Novel Biomedical Co., Ltd. | 028-85255396 18302801538 | cdnovell@163.com | China | 2314 | 58 |
View Lastest Price from MELOXICAM-D3 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-24 | Meloxicam-d3
942047-63-4
|
US $596.00-1830.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2023-05-27 | Meloxicam D3
942047-63-4
|
US $13000.00-24000.00 / mg | 10mg | 96% | 100 | Simson Pharma limited |
-
- Meloxicam-d3
942047-63-4
- US $596.00-1830.00 / mg
- TargetMol Chemicals Inc.
-
- Meloxicam D3
942047-63-4
- US $13000.00-24000.00 / mg
- 96%
- Simson Pharma limited