ChemicalBook >> CAS DataBase List >>Fleroxacin
Fleroxacin
- CAS No.
- 79660-72-3
- Chemical Name:
- Fleroxacin
- Synonyms
- AM-833;QUINODIS;MEGALONE;MEGALOCIN;RO-23-6240;FLEROXACIN;ro23-6240/000;Fleroxacin>Fleroxacin, >=99%;Erlotinib-d12 HCl
- CBNumber:
- CB1331989
- Molecular Formula:
- C17H18F3N3O3
- Molecular Weight:
- 369.34
- MDL Number:
- MFCD00864880
- MOL File:
- 79660-72-3.mol
- MSDS File:
- SDS
Last updated:2024-11-20 11:41:24
| Melting point | 264-266°C |
|---|---|
| Boiling point | 535.3±50.0 °C(Predicted) |
| Density | 1.409±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 0.1 M NaOH: soluble10mg/mL |
| pka | -0.54±0.20(Predicted) |
| form | solid |
| color | white to off-white |
| Merck | 14,4099 |
| CAS DataBase Reference | 79660-72-3(CAS DataBase Reference) |
| FDA UNII | N804LDH51K |
| ATC code | J01MA08 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H371 |
| Precautionary statements | P260-P264-P270-P308+P311-P405-P501 |
| WGK Germany | 2 |
| RTECS | VB1999050 |
| HS Code | 29335990 |
Fleroxacin price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | F6807 | Fleroxacin ≥98% (HPLC) | 79660-72-3 | 1g | $631 | 2023-06-20 | Buy |
| Sigma-Aldrich | 33930 | Fleroxacin VETRANAL?, analytical standard | 79660-72-3 | 100MG | $122 | 2022-05-15 | Buy |
| TCI Chemical | F0646 | Fleroxacin >98.0%(T) | 79660-72-3 | 5g | $147 | 2024-03-01 | Buy |
| TCI Chemical | F0646 | Fleroxacin >98.0%(T) | 79660-72-3 | 25g | $574 | 2024-03-01 | Buy |
| Cayman Chemical | 24173 | Fleroxacin ≥98% | 79660-72-3 | 1g | $57 | 2024-03-01 | Buy |
Fleroxacin Chemical Properties,Uses,Production
Description
Fleroxacin is a new, once daily trifluoroquinolone antibacterial structurally related to norfloxacin. Available in both oral and IV formulations, it is reportedly useful in the treatment of gonorrhea, bacterial enteritis, chronic bronchitis and urinary tract infections. Fleroxacin has a longer serum half-life (9-12 hours) than other drugs of this class, such as ciprofloxacin, enoxacin and norfloxacin.
Chemical Properties
White Needle-Like Crystals
Originator
Kyorin (Japan)
Uses
An antibacterial.
Uses
antibiotic
Definition
ChEBI: A fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-n gative bacteria.
Manufacturing Process
6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-
oxoquinoline-3-carboxylic acid hydrochloride:
A mixed solution of 1-methylpiperazine (0.34 g) and pyridine (3 ml) was
added to 6,7,8-trifluoro-1-(2-fluoroethyl)-1,4-dihydro-4-oxoquinoline-3-
carboxylic acid (0.12 g) and heated to reflux for 6 hours. After the solvent
evaporated and cooled, the residue was adjusted to pH 1 with aqueous
hydrochloric acid. The cooled mixture was filtered off and the solid
recrystallized from water to give 6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-
(4-methyl-1-piperazinyl)-4-oxoquinoline-3-carboxylic acid hydrochloride (0.08
g), melting point 269-271°C (decomp.).
brand name
Quinodis
Therapeutic Function
Antibacterial
Fleroxacin Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Global( 289)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8810 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12834 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5889 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20284 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8618959220845 | sales@amoychem.com | China | 6383 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
Related articles
- Uses of Fleroxacin
- Fleroxacin (Ro 23-6240, AM 833) is different from fluoroquinolones such as ciprofloxacin or ofloxacin, since it is a trifluori....
- Mar 25，2022
View Lastest Price from Fleroxacin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | Fleroxacin
79660-72-3
|
US $40.00 / g | 99.34% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-19 | Fleroxacin
79660-72-3
|
US $40.00 / g | 99.34% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-18 | Fleroxacin
79660-72-3
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Weibang Biotechnology Co., Ltd |
-
- Fleroxacin
79660-72-3
- US $40.00 / g
- 99.34%
- TargetMol Chemicals Inc.
-
- Fleroxacin
79660-72-3
- US $40.00 / g
- 99.34%
- TargetMol Chemicals Inc.
-
- Fleroxacin
79660-72-3
- US $10.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd
AM-833, Ro-23-6240, Megalocin, Megalone, Quinodis, 6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid
AM-833, Megalocin, Megalone, 6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methylpiperazino)-4-oxo-3-quinolinecarboxylic acid, 6,8-Difluoro-1-(2-fluoroethyl)1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-4-oxo-7-(4-methyl-1-piperazinyl)quinoline-3-carboxylic acid
6,8-difluoro-1-(2-fluoroethyl)-4-keto-7-(4-methylpiperazin-1-yl)quinoline-3-carboxylic acid
6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid
6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylicacid
6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid
Megalone
Fleroxacin Solution, 100ppm
RO-23-6240
QUINODIS
3-quinolinecarboxylicacid,1,4-dihydro-6,8-difluoro-1-(2-fluoroethyl)-7-(4-met
hyl-1-piperazinyl)-4-oxo-
ro23-6240/000
Fleroxacin solution,1000ppm
Fleroxacin, >=99%
FLEROXACIN
MEGALOCIN
MEGALONE
AM-833
6,8-DIFLUORO-1-(2-FLUOROETHYL)-1,4-DIHYDRO-7-(4-METHYL-1-PIPERAZINYL)-4-OXO-3-QUINOLINECARBOXYLIC ACID
6,8-DIFLUORO-1-(2-FLUOROETHYL)-1,4-DIHYDRO-7-(4-METHYLPIPERAZINO)-4-OXO-3-QUINOLINECARBOXYLIC ACID
Erlotinib-d12 HCl
6,8-difluoro-1-(2-fluoroethyl)-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
Fleroxacin>
Fleroxacin Fleroxacin
Fleroxacin, 98%, for analysis
3-Quinolinecarboxylic acid, 6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-
Fleroxacin USP/EP/BP
6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-4-ium-1-yl)-4-oxoquinoline-3-carboxylate
6,8-Difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Fluorine Rosa star
6,8-Difluoro-1-(2-fluoroethyl)-7-(4-methyl-1-piperazinyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid
C13658000 Fleroxacin
Fleroxacin in Methanol
79660-72-3
79960-72-3
79660-72-7
C17H18F3NC3H6O3
C17H18F3N3O3
Quinodis, Megalocin
Antibiotics for Research and Experimental Use
Biochemistry
Quinolones (Antibiotics for Research and Experimental Use)
Intermediates & Fine Chemicals
Pharmaceuticals