1-Dodecanol
- CAS No.
- 112-53-8
- Chemical Name:
- 1-Dodecanol
- Synonyms
- Fatty alcohol;LAURYL ALCOHOL;DODECANOL;dodecyl;lauryl;DODECAN-1-OL;Pisol;Lauric Alcohol;DODECYL ALCOHOL;Lorol
- CBNumber:
- CB1334632
- Molecular Formula:
- C12H26O
- Molecular Weight:
- 186.33
- MDL Number:
- MFCD00004753
- MOL File:
- 112-53-8.mol
- MSDS File:
- SDS
| Melting point | 22-26 °C(lit.) |
|---|---|
| Boiling point | 260-262 °C(lit.) |
| Density | 0.833 g/mL at 25 °C(lit.) |
| vapor density | 7.4 (vs air) |
| vapor pressure | 0.1 mm Hg ( 20 °C) |
| FEMA | 2617 | LAURYL ALCOHOL |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Store below +30°C. |
| solubility | water: slightly soluble1g/L at 23°C |
| form | Liquid |
| pka | 15.20±0.10(Predicted) |
| color | APHA: ≤10 |
| Odor | Typical fatty alcohol odor; sweet. |
| explosive limit | 4% |
| Odor Type | waxy |
| Viscosity | 11.251mm2/s |
| Water Solubility | insoluble |
| JECFA Number | 109 |
| Merck | 14,3405 |
| BRN | 1738860 |
| Dielectric constant | 6.5（24℃） |
| InChIKey | LQZZUXJYWNFBMV-UHFFFAOYSA-N |
| LogP | 5.4 at 23℃ |
| Substances Added to Food (formerly EAFUS) | LAURYL ALCOHOL |
| FDA 21 CFR | 175.105; 175.300; 177.1200 |
| CAS DataBase Reference | 112-53-8(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 178A96NLP2 |
| NIST Chemistry Reference | 1-Dodecanol(112-53-8) |
| EPA Substance Registry System | 1-Dodecanol (112-53-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319-H410 | |||||||||
| Precautionary statements | P264-P273-P280-P305+P351+P338-P337+P313-P391 | |||||||||
| Hazard Codes | Xi,N | |||||||||
| Risk Statements | 38-50-50/53-36/38-36/37/38 | |||||||||
| Safety Statements | 61-37/39-29-26-60-36 | |||||||||
| RIDADR | UN 3077 9/PG 3 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | JR5775000 | |||||||||
| Autoignition Temperature | 500 °F | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 9 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29051700 | |||||||||
| Toxicity | LD50 orally in Rabbit: > 5000 mg/kg | |||||||||
| NFPA 704 |
|
1-Dodecanol price More Price(59)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | W261718 | Lauryl alcohol ≥98%, FG | 112-53-8 | 1kg | $77.5 | 2024-03-01 | Buy |
| Sigma-Aldrich | W261718 | Lauryl alcohol ≥98%, FG | 112-53-8 | 4kg | $177 | 2024-03-01 | Buy |
| Sigma-Aldrich | W261718 | Lauryl alcohol ≥98%, FG | 112-53-8 | 8kg | $282 | 2024-03-01 | Buy |
| Sigma-Aldrich | W261718 | Lauryl alcohol ≥98%, FG | 112-53-8 | 20kg | $489 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHR2599 | Lauryl Alcohol Pharmaceutical Secondary Standard; Certified Reference Material | 112-53-8 | 1G | $132 | 2024-03-01 | Buy |
1-Dodecanol Chemical Properties,Uses,Production
Physical properties
1-Dodecanol is a white low melting crystalline solid that has a melting point of 24°C.The air odor threshold for dodecyl alcohol (isomer not specified) is reported to be 7.1 ppb.
Chemical Properties
Lauryl alcohol has a characteristic fatty odor; unpleasant at high concentrations, but delicate and floral on dilution. 1-Dodecanol is a saturated 12-carbon fatty alcohol obtained from coconut oil fatty acids. It has a fatty, waxy flavor and is used in detergents, lubricating oils, and pharmaceuticals.
Occurrence
Reported found in the oil of Mexican lime and in the oil from flowers of Furcraea gigantean. Also reported found in apple, banana, sour cherry, citrus peel oils, melon, pineapple, potato, thymus, cheeses, butter, milk powder, chicken and beef fat, cooked pork, beer, whiskies, white wine, peanuts, beans, mushrooms, mango, coriander seed and leaf, rice, Bourbon vanilla, endive, crab, clam, Cape gooseberry, pawpaw and maté.
Uses
1-Dodecanol is used in chemical formulations for a variety of purposes, including as an emulsion stabilizer, a skin-conditioning emollient, and a viscosity-increasing agent.
Uses
1-Dodecanol is used as a cosmetic, textile auxiliaries, synthetic oil, emulsifiers and flotation agent of raw materials, a detergent raw material, a foaming agent of the toothpaste.
Production Methods
1-Dodecanol is produced commercially by the oxo process and from ethylene by the Ziegler process, which involves oxidation of trialkylaluminum compounds. It can also be produced by sodium reduction or high-pressure hydrogenation of esters of naturally occurring lauric acid.
Preparation
Commercially 1-Dodecanol may be prepared by hydrogenation of lauric acid; normally employed as a replacement for the corresponding aldehyde.
Definition
ChEBI: 1-Dodecanol is a fatty alcohol that is dodecane in which a hydrogen from one of the methyl groups is replaced by a hydroxy group. It is registered for use in apple and pear orchards as a Lepidopteran pheromone/sex attractant, used to disrupt the mating behaviour of certa n moths whose larvae destroy crops.
Aroma threshold values
Detection: 73 to 820 ppb
Synthesis Reference(s)
Journal of the American Chemical Society, 108, p. 6036, 1986 DOI: 10.1021/ja00279a061
Tetrahedron Letters, 37, p. 3623, 1996 DOI: 10.1016/0040-4039(96)00652-1
General Description
Colorless thick liquid with a sweet odor. Floats on water. Freezing point is 75°F.
Reactivity Profile
Dodecyl alcohol is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.
Health Hazard
Liquid will cause burning of the eyes and may irritate skin.
Flammability and Explosibility
Non flammable
Safety Profile
Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. A severe human skin irritant. Questionable carcinogen with experimental tumorigenic data. Combustible when exposed to heat or flame; can react with oxidizing materials. To fight fire, use dry chemical, CO2. When heated to decomposition it emits acrid smoke and irritating fumes
Carcinogenicity
1-Dodecanol showed weak tumor-promoting activity when applied three times a week for 60 weeks to the skin of mice that had previously received an initiating dose of dimethylbenz[a]anthracene. Papillomas developed in 2 of 30 mice after 39 and 49 weeks of treatment.
Purification Methods
Crystallise dodecanol from aqueous EtOH, and distil it through a spinning-band column under vacuum. [Ford & Marvel Org Synth 10 62 1930, Beilstein 1 IV 1844.]
1-Dodecanol Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of5
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18153 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3002 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8810 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12841 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5892 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 3010 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 | kaia@neputrading.com | China | 1001 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
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View Lastest Price from 1-Dodecanol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-29 | 1-Dodecanol
112-53-8
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-11-29 | 1-Dodecanol
112-53-8
|
US $60.00 / kg | 1kg | 99 | 5000 | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2024-11-29 | Dodecyl alcohol
112-53-8
|
US $150.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd |
-
- 1-Dodecanol
112-53-8
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 1-Dodecanol
112-53-8
- US $60.00 / kg
- 99
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- Dodecyl alcohol
112-53-8
- US $150.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd