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ATP disodium salt

CAS No.
987-65-5
Chemical Name:
ATP disodium salt
Synonyms
ADENOSINE TRIPHOSPHATE DISODIUM;ATP-NA2;ATP DISODIUM SALT;ADENOSINE TRIPHOSPHATE, DISODIUM SALT;ATP 2NA;ATP DISODIUM;Adenosine 5'-triphosphate disodium salt;Adetide;551.145;adetphos
CBNumber:
CB1360204
Molecular Formula:
C10H17N5NaO13P3
Molecular Weight:
531.18
MDL Number:
MFCD00080339
MOL File:
987-65-5.mol
MSDS File:
SDS
Last updated:2026-01-04 19:55:51
Product description Number Pack Size Price
Adenosine 5′-triphosphate disodium salt solution Crystalline ATP, HPLC purified, aqueous solution for RNA transcription A6559 25μmol $123
Adenosine 5?-Triphosphate, Disodium, Trihydrate, Low Metals Grade - CAS 987-65-5 - Calbiochem Lowmetalsgrade.Speciallyprocessedtoreducelevelsofcontaminatingmetals. 119125 1g $143
Adenosine 5'-triphosphate (sodium salt) ≥95% 14498 5g $57
Adenosine 5'-triphosphate (sodium salt) ≥95% 14498 10g $100
Adenosine 5'-triphosphate (sodium salt) ≥95% 14498 25g $233
More product size

ATP disodium salt Properties

Melting point 188~190℃
Density 1.85 at 20℃
vapor pressure 0.1Pa at 20-50℃
storage temp. -20°C
solubility H2O: 50 mg/mL
form crystalline
color White powder
PH Range 2.5 - 3.5
Water Solubility Soluble in water
Merck 155
Cosmetics Ingredients Functions SKIN CONDITIONING
InChIKey TTWYZDPBDWHJOR-IDIVVRGQSA-L
LogP -2.66 at 24℃ and pH7
Surface tension 67.86mN/m at 1.019g/L and 20℃
CAS DataBase Reference 987-65-5(CAS DataBase Reference)
FDA UNII 5L51B4DR1G
EPA Substance Registry System Adenosine 5'-(tetrahydrogen triphosphate), disodium salt (987-65-5)
UNSPSC Code 41106305
NACRES NA.52

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-36-26
WGK Germany  3
RTECS  AU7417000
10-21
TSCA  TSCA listed
HS Code  29389090

ATP disodium salt price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A6559 Adenosine 5′-triphosphate disodium salt solution Crystalline ATP, HPLC purified, aqueous solution for RNA transcription 987-65-5 25μmol $123 2025-07-31 Buy
Sigma-Aldrich 119125 Adenosine 5?-Triphosphate, Disodium, Trihydrate, Low Metals Grade - CAS 987-65-5 - Calbiochem Lowmetalsgrade.Speciallyprocessedtoreducelevelsofcontaminatingmetals. 987-65-5 1g $143 2025-07-31 Buy
Cayman Chemical 14498 Adenosine 5'-triphosphate (sodium salt) ≥95% 987-65-5 5g $57 2024-03-01 Buy
Cayman Chemical 14498 Adenosine 5'-triphosphate (sodium salt) ≥95% 987-65-5 10g $100 2024-03-01 Buy
Cayman Chemical 14498 Adenosine 5'-triphosphate (sodium salt) ≥95% 987-65-5 25g $233 2024-03-01 Buy
Product number Packaging Price Buy
A6559 25μmol $123 Buy
119125 1g $143 Buy
14498 5g $57 Buy
14498 10g $100 Buy
14498 25g $233 Buy

ATP disodium salt Chemical Properties,Uses,Production

Description

ATP disodium salt (Adenosine 5'-triphosphate disodium salt, ATP-Na2) is an organic sodium salt. It consists of an ATP and a ({(2R,3S,4R,5R)-3,4-dihydroxy-5-(9h -purin-9-yl)oxolan-2-yl)methylphosphonatooxy)phosphonate. It has the role of providing a source of energy for cells and is a central component of energy storage and metabolism in the body. ATP disodium salt is an important endogenous signalling molecule in immunity and inflammation. It is an important component in the study of various physiological and biochemical processes. It is involved in a variety of cellular functions such as muscle contraction, nerve impulse transmission and membrane transport, making it a fundamental molecule for understanding biological mechanisms. It can also be used to photometrically determine Luc activity in cell extracts.

Chemical Properties

White powder

Application

In biochemical research. To inhibit enzymatic browning of raw edible plant materials, such as sliced apples, potatoes, etc.

Uses

A metabolite of Adenosine (A280400), a multifunctional nucleoside triphosphate used in cells as a coenzyme of intracellular energy transfer. It transports chemical energy within cells for metabolism. ATP Disodium Salt (ATP-Na2) is used in the synthetic preparation of ribose-modified deoxyadenosine bisphosphate analogues as P2Y1 receptor ligands.

Biological Activity

P2 purinoceptor agonist.

Biochem/physiol Actions

Adenosine 5′-triphosphate (ATP) is an important energy currency in all living organisms. It possesses high phosphate transfer potential. ATP is involved in several biological processes such as membrane transport, muscle contraction and synthesis, and degradation of biological molecules. It plays a role as an intracellular and extracellular signaling molecule in certain cellular processes such as cell motility, organ development, neurotransmission, and insulin secretion.

in vitro

ATP disodium salt (5mM; 1 hour) co-treatment with LPS (1 μg/ml) has a synergistic effect on activating the NLRP3 inflammasome in HGFs.
ATP disodium salt (2 mM; 0.5-24 hours) induces the secretion of interleukin 1β, KC, and MIP-2 from bone marrow-derived macrophages (BMDMs) in vitro in a caspase-1 activation-dependent manner.
ATP disodium salt stimulates cytokine and chemokine secretion, and inflammasome activation, directly and indirectly, induces in vitro neutrophil chemotaxis.

in vivo

ATP disodium salt (50 mg/kg; i.p.) protects mice against bacterial infection in vivo.
ATP disodium salt induces the secretion of IL1β, KC and MIP-2 and neutrophils recruitment in vivo.

storage

Store at -20°C

Toxicity evaluation

ATP disodium salt (ATP-Na2) was administered by gavage to rats for 90 consecutive days at doses of 0 (control), 500, 1000, and 2000 mg kg BW?1·d?1 (n = 10 per sex/group). Subchronic administration of ATP was well tolerated at all dose levels. Body weights and feed consumption body weight gains were similar between ATP-treated and control rats. Minor differences were seen in hematology and blood chemistry; however, these changes were not dose-related and, therefore, not of biological or toxicological significance. Only one difference was observed in absolute organ weights; females of the high dose had increased kidney and increased relative kidney and liver weights; however, these differences were not seen in males nor appeared to be dose-related[1].

References

[1] Ralf Jger, John C. Fuller Jr., Martin Purpura . “Subchronic (90-Day) repeated dose toxicity study of disodium adenosine-5′-triphosphate in rats.” Regulatory Toxicology and Pharmacology 116 (2020): Article 104760.

ATP disodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 727)Suppliers
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Hangzhou Lucky Biology Co., Ltd
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citric acid pictures 2026-01-04 citric acid
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ATP disodium salt pictures 2026-01-04 ATP disodium salt
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US $46.00 / g 98.72% 10g TargetMol Chemicals Inc.
ATP disodium salt pictures 2026-01-04 ATP disodium salt
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US $46.00 / g 98.72% 10g TargetMol Chemicals Inc.
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