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ChemicalBook >> CAS DataBase List >>2-(2-methylbutylamino)-1-[4-[(3-methylphenoxy)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl]ethanone:hydrochloride

2-(2-methylbutylamino)-1-[4-[(3-methylphenoxy)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl]ethanone:hydrochloride

2-(2-methylbutylamino)-1-[4-[(3-methylphenoxy)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl]ethanone:hydrochloride Structure
2-(2-methylbutylamino)-1-[4-[(3-methylphenoxy)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl]ethanone:hydrochloride structure
CAS No.
1782573-67-4
Chemical Name:
2-(2-methylbutylamino)-1-[4-[(3-methylphenoxy)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl]ethanone:hydrochloride
Synonyms
RU-SKI 43 HCL;HHAT INHIBITOR;RUSKI 43 hydrochloride,RU SKI 43 hydrochloride;2-(2-methylbutylamino)-1-[4-[(3-methylphenoxy)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl]ethanone:hydrochloride
CBNumber:
CB13831060
Molecular Formula:
C22H31ClN2O2S
Molecular Weight:
423.01
MDL Number:
MFCD25371547
MOL File:
1782573-67-4.mol
Last updated:2024-07-02 08:55:00
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2-(2-methylbutylamino)-1-[4-[(3-methylphenoxy)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl]ethanone:hydrochloride Properties

storage temp. Store at -20°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
form A crystalline solid
color White to off-white

2-(2-methylbutylamino)-1-[4-[(3-methylphenoxy)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl]ethanone:hydrochloride price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 16972 RU-SKI 43 (hydrochloride) 1782573-67-4 1mg $37 2024-03-01 Buy
Cayman Chemical 16972 RU-SKI 43 (hydrochloride) 1782573-67-4 10mg $213 2024-03-01 Buy
Cayman Chemical 16972 RU-SKI 43 (hydrochloride) 1782573-67-4 5mg $142 2024-03-01 Buy
Axon Medchem Axon2035 RU-SKI43hydrochloride 99% 1782573-67-4 2x5mg $176 2021-12-16 Buy
ChemScene CS-3457 RU-SKI43hydrochloride 98.54% 1782573-67-4 10mg $192 2021-12-16 Buy
Product number Packaging Price Buy
16972 1mg $37 Buy
16972 10mg $213 Buy
16972 5mg $142 Buy
Axon2035 2x5mg $176 Buy
CS-3457 10mg $192 Buy

2-(2-methylbutylamino)-1-[4-[(3-methylphenoxy)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl]ethanone:hydrochloride Chemical Properties,Uses,Production

Description

Hedgehog acyltransferase (Hhat) is an N-palmitoyltransferase that acylates Sonic hedgehog (Shh), which is critical for signaling through Shh. RU-SKI 43 is an inhibitor of Hhat (IC50 = 0.85 μM). It blocks palmitoylation of Shh without affecting palmitoylation of H-Ras or Fyn, myristoylation of c-Src, or acylation of Wnt3a. RU-SKI 43 is cell-permeable and inhibits both autocrine and paracrine Shh-induced activation of Gli-mediated transcription. In pancreatic cancer cells, RU-SKI 43 reduces both Gli1 activation and proliferation.

2-(2-methylbutylamino)-1-[4-[(3-methylphenoxy)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl]ethanone:hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

2-(2-methylbutylamino)-1-[4-[(3-methylphenoxy)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl]ethanone:hydrochloride Suppliers

Global( 13)Suppliers
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TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9707 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Absin Bioscience Inc. 021-38015121 15000105423 chenjw@absin.cn China 24734 58
Shanghai hongqu biomedical technology co. LTD 88888888888 hongquchem@qq.com China 5132 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29778 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 23963 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9268 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Absin Bioscience Inc. 58
Shanghai hongqu biomedical technology co. LTD 58
MedBioPharmaceutical Technology Inc 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
RD International Technology Co., Limited 58
2-(2-methylbutylamino)-1-[4-[(3-methylphenoxy)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl]ethanone:hydrochloride RU-SKI 43 HCL;HHAT INHIBITOR RUSKI 43 hydrochloride,RU SKI 43 hydrochloride 1782573-67-4