(5Z,9Z,13E)-6,10,14,18-tetramethylnonadeca-5,9,13,17-tetraen-2-one
- CAS No.
- 3879-24-1
- Chemical Name:
- (5Z,9Z,13E)-6,10,14,18-tetramethylnonadeca-5,9,13,17-tetraen-2-one
- Synonyms
- (5Z,9Z,13E)-Teprenone;(5Z,9Z,13E)-Geranylgeranylacetone
- CBNumber:
- CB13936620
- Molecular Formula:
- C23H38O
- Molecular Weight:
- 330.54722
- MDL Number:
- MFCD00869547
- MOL File:
- 3879-24-1.mol
(5Z,9Z,13E)-6,10,14,18-tetramethylnonadeca-5,9,13,17-tetraen-2-one Chemical Properties,Uses,Production
Uses
(5Z,9Z,13E)-Geranylgeranylacetone is the structural analogue of Teprenone (T103500), an anti-ulcerative. Geranylgeranylacetone can induce expression of HSP70, HSPB8, and HSPB1. Induction of HSP70 expression is protective against the development of various diseases, such as inflammatory bowel disease, hypoxic/ischemic brain injury and spinal and bulbar muscular atrophy (cytoprotective and anti-inflammatory effects). Reports indicate that GGA protects against NSAID-induced gastric and intestinal lesions by induction of HSP70 expression. Other studies have shown that GGA induces expression of HSPB8 and HSPB1 and reduces the formation of amyloid oligomers as well as insoluble aggregates in HSPB5 R120G TG mice.
(5Z,9Z,13E)-6,10,14,18-tetramethylnonadeca-5,9,13,17-tetraen-2-one Preparation Products And Raw materials
Raw materials
Preparation Products
(5Z,9Z,13E)-6,10,14,18-tetramethylnonadeca-5,9,13,17-tetraen-2-one Suppliers
Global( 5)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
QUALITY CONTROL SOLUTIONS LTD. | 13670046396 | ORDERS@QCSRM.COM | China | 18865 | 58 |
Cato Research Chemicals Inc. | 020-81960175-877 18933936954 | tianwen.zhan@cato-chem.com | China | 7736 | 58 |
Supplier | Advantage |
---|---|
China National Standard Pharmaceutical Corporation Limited | 58 |
BOC Sciences | 65 |
BOC Sciences | 65 |
QUALITY CONTROL SOLUTIONS LTD. | 58 |
Cato Research Chemicals Inc. | 58 |
(5Z,9Z,13E)-Geranylgeranylacetone
(5Z,9Z,13E)-Teprenone
3879-24-1