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2-Amino-2-phenylacetic acid

2-Amino-2-phenylacetic acid structure

CAS No.: 2835-06-5

Chemical Name:: 2-Amino-2-phenylacetic acid

Synonyms: 2-Phenylglycine;α-phenylglycine;H-DL-PHG-OH;DL-ALPHA-PHENYLGLYCINE;DL-PHENYLGLYCINE;DL-2-PHENYLGLYCINE;DL-α-Phenylglycine;2-Amino-2-phenyL;DL-A-PHENYLGLYCINE;RARECHEM AK ML 0501

CBNumber:: CB1420201

Molecular Formula:: C8H9NO2

Molecular Weight:: 151.16

MDL Number:: MFCD00064402

MOL File:: 2835-06-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-04 10:33:10

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2-Amino-2-phenylacetic acid Properties

Melting point	290 °C (subl.)(lit.)
alpha	[α]D20-0.5～+0.5゜ (c=5, dil. HCl)
Boiling point	273.17°C (rough estimate)
Density	1.2023 (rough estimate)
refractive index	1.5810 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	almost transparency in Sodium hydroxide solution
pka	1.94±0.10(Predicted)
form	Crystalline Powder
color	White to off-white
Water Solubility	115g/L(100 ºC)
Merck	14,7291
BRN	3197862
Major Application	detection
InChI	1S/C8H9NO2/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7H,9H2,(H,10,11)
InChIKey	ZGUNAGUHMKGQNY-UHFFFAOYSA-N
SMILES	NC(C(O)=O)c1ccccc1
CAS DataBase Reference	2835-06-5(CAS DataBase Reference)
FDA UNII	96S7ZZ1KHE
NIST Chemistry Reference	Benzeneacetic acid, «alpha»-amino-, (.+/-.)-(2835-06-5)
EPA Substance Registry System	2-Phenylglycine (2835-06-5)
UNSPSC Code	12352209
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P305+P351+P338

PPE

Eyeshields, Gloves, type N95 (US)

Hazard Codes

F,C

Risk Statements

11-34

Safety Statements

24/25-45-36/37/39-26-16

WGK Germany

TSCA

TSCA listed

HS Code

29224999

Storage Class

11 - Combustible Solids

NFPA 704

	1
2		0

2-Amino-2-phenylacetic acid price More Price(60)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	P25507	2-Phenylglycine 95%	2835-06-5	100g	$60.8	2026-04-30	Buy
TCI Chemical	P0326	DL-2-Phenylglycine >98.0%(HPLC)(T)	2835-06-5	25g	$25	2026-04-30	Buy
TCI Chemical	P0326	DL-2-Phenylglycine >98.0%(HPLC)(T)	2835-06-5	500g	$284	2026-04-30	Buy
Cayman Chemical	37186	Phenylglycine ≥95%	2835-06-5	50g	$28	2026-04-30	Buy
Cayman Chemical	37186	Phenylglycine ≥95%	2835-06-5	100g	$53	2026-04-30	Buy

Product number	Packaging	Price	Buy
P25507	100g	$60.8	Buy
P0326	25g	$25	Buy
P0326	500g	$284	Buy
37186	50g	$28	Buy
37186	100g	$53	Buy

2-Amino-2-phenylacetic acid Chemical Properties,Uses,Production

Description

2-Amino-2-phenylacetic acid is a natural compound that has been identified as a selective inhibitor of cyclooxygenase 2 (COX-2), and it exhibits antiinflammatory activity. It has been shown to inhibit COX-2 at low concentrations and to be less potent than aspirin in inhibiting COX-1. It is also an amide, with a molecular weight of 296. In order to determine the structure of it, XRD data was collected from the monosodium salt form of the compound. The ester hydrochloride form was used for enzyme activity assays because it is more soluble in water than the free base form. The synthesis of 2-Amino-2-phenylacetic acid was achieved through a two step process involving amide formation and hydrolysis.

Chemical Properties

white amorphous powder

Uses

DL-α-Phenylglycine is used as a reagent in the synthesis of benzoquinone-amino acid conjugates which have antibacterial activity.

Definition

ChEBI: An amino acid with a structure in which a phenyl ring is bonded to the alpha-carbon of glycine.

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 3, p. 84, 1955
Synthetic Communications, 2, p. 423, 1972 DOI: 10.1080/00397917208081791

reaction suitability

reaction type: solution phase peptide synthesis

2-Amino-2-phenylacetic acid synthesis

Synthesis of 2-Amino-2-phenylacetic acid from Benzoylformic acid

2-Amino-2-phenylacetic acid Preparation Products And Raw materials

Raw materials

4-Chlorobenzaldehyde Sodium cyanide Ammonium bicarbonate Glyoxylic acid

Preparation Products

1-Methyl-3-phenylpiperazine Fmoc-L-phenylglycine (S)-(+)-N-(3,5-Dinitrobenzoyl)-alpha-phenylglycine 5-Phenylhydantoin Amino-cyclohexyl-acetic acid

2-Bromo-2-phenylacetic acid 2-[(4-methoxyphenyl)formamido]-2-phenylacetic acid Benzeneacetic acid, α-[(2-furanylcarbonyl)amino]- (2-Oxo-pyrrolidin-1-yl)-phenyl-acetic acid

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2-Amino-2-phenylacetic acid Suppliers

Global( 351)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Yangzhou Aoxin Chemical Co., Ltd	0514-87754778 13901446058	sales@aochem.com	China	69	66
ShangHai DEMO Chemical Co.,Ltd	400-021-7337 2355568890	sales@demochem.com	China	2569	57
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Beijing Ouhe Technology Co., Ltd	13552068683 13522913783	2355560935@qq.com	China	11777	60

Supplier	Advantage
Shanghai YuanYe Biotechnology Co., Ltd.	60
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81
Yangzhou Aoxin Chemical Co., Ltd	66
ShangHai DEMO Chemical Co.,Ltd	57
Energy Chemical	61
Capot Chemical Co., Ltd	66
Beijing Ouhe Technology Co., Ltd	60

Application Research of 2-Phenylglycine and its derivatives
2-Phenylglycine, a chiral amino acid, is a core intermediate for synthesizing semisynthetic antibiotics and pesticides.
Feb 11,2026

View Lastest Price from 2-Amino-2-phenylacetic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-11	DL-Phenylglycine 2835-06-5		1KG	98%min	500kgs	WUHAN FORTUNA CHEMICAL CO., LTD
2026-08-25	2-Amino-2-phenylacetic acid 2835-06-5	$2.00-5.00	1kg	99%	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2026-07-04	2-Phenylglycine 2835-06-5			98.84%	10g	TargetMol Chemicals Inc.

DL-Phenylglycine
2835-06-5
$0.00
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

2-Amino-2-phenylacetic acid
2835-06-5
$2.00-5.00
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

2-Phenylglycine
2835-06-5
$0.00
98.84%
TargetMol Chemicals Inc.

2-Amino-2-phenylacetic acid Spectrum

2-Amino-2-phenylacetic acid(2835-06-5)MS 2-Amino-2-phenylacetic acid(2835-06-5)¹HNMR 2-Amino-2-phenylacetic acid(2835-06-5)IR1 2-Amino-2-phenylacetic acid(2835-06-5)IR2 2-Amino-2-phenylacetic acid(2835-06-5)Raman

2835-06-5(2-Amino-2-phenylacetic acid)Related Search:

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Iminodiacetic acid Nitrilotriacetic acid Anilinoacetic acid Glycine Sulfanilamide

Aminoethoxyvinyl glycine hydrochloride 2-Aminophenylacetic acid 2-Aminophenylacetic acid

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RARECHEM AK ML 0501 (.+/-.)-alpha-Phenylglycine (+/-)-benzeneaceticaci .alpha.-amino-,(+-)-Benzeneaceticacid -Aminobenzeneaceticacid Benzeneacetic acid, alpha-amino-, (± Benzeneaceticacid,-amino-,(+-)- PHENYLGLYCINE(D,L-) DL-A-AMINOPHENYLACETIC ACID CRYSTALLINE Benzeneacetic acid, alpha-amino- (9CI) Benzeneacetic acid, .alpha.-amino- (n)-à-aminophenylacetic acid 2-Amino-2-phenylacetic acid DL-a-Aminophenylglycine acid (±)-α-Aminophenylacetic acid, DL-α-Phenylglycine DL-α-Aminophenylacetic acid 2-Phenyl-DL-glycine rac-(R*)-Aminophenylacetic acid DL-alpha-Phenylglycine,99% DL-2-Phenylglycine (±)-α-Aminophenylacetic acid 2-Phenylglycine,(±)-α-Aminophenylacetic acid, DL-α-Phenylglycine DL-alpha-Phenylglycine, 99% 100GR (-)-1-phenylglycine DL-A-AMINOPHENYLACETIC ACID FOR SYNTHESI Benzeneaceticacid,a-aMino- Glycine, 2-phenyl-, DL- AMINO-PHENYL-ACETIC ACID 2-Phenylglycine 95% DL-A-AMINOPHENYLACETIC ACID DL-2-AMINOPHENYLACETIC ACID DL-A-PHENYLGLYCINE DL-ALPHA-PHENYLAMINOACETIC ACID DL-ALPHA-AMINOPHENYLACETIC ACID LABOTEST-BB LT00005726 H-DL-(PHENYL)GLY-OH Mezlocillin Impurity 6 2-Amino-2-phenyL Clopidogrel Impurity 28 DL-α-Phenylg151.16 lycine DL-2-Phenylglycine> 2-Amino-2-phenylacetic acid USP/EP/BP Chemical Reagent Bloom Tech 2-Amino-2-Phenylacetic Acid CAS?2835-06-5 DL-Phenyl glycine, GR 99%+ DL-2-PHENYLGLYCINE DL-ALPHA-PHENYLGLYCINE DL-PHENYLGLYCINE DL-α-Phenylglycine 2-Phenylglycine,lactation,Endogenous Metabolite,inhibit,2Phenylglycine,breast,period,milk,Inhibitor,2 Phenylglycine Benzeneacetic acid, α-amino- (+/-)-Alpha-AMinophenylacetic Acid 2-Phenylglycine, 98% H-DL-PHG-OH 2-Phenylglycine α-phenylglycine 2835-06-5 835-06-5 2383-06-5 2835-06-05