HUMAN IGFBP-3
- CAS No.
- Chemical Name:
- HUMAN IGFBP-3
- Synonyms
- IBP3;IBP-3;IGFBP-3;HUMAN IGFBP-3;IGFBP-3, HUMAN;IGF BINDING PROTEIN-3;IGF-Binding Protein-3 human;IGF Binding Protein-3, IGFBP-3;Growth-hormone-dependant binding protein;Recombinant Human IGFBP3 Protein, His Tag
- CBNumber:
- CB1432006
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00285941
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Hazard Codes | T,C,F |
|---|---|
| Risk Statements | 23/24/25-36/37/38-52/53-35-20/21/22-11 |
| Safety Statements | 26-36/37/39-45-61 |
| WGK Germany | 3 |
HUMAN IGFBP-3 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 155195 | Insulin Like Growth Factor Binding Protein 3 | 10ug | $343 | 2021-12-16 | Buy | |
| Usbiological | 155196 | Insulin Like Growth Factor Binding Protein 3 | 10ug | $345 | 2021-12-16 | Buy | |
| Usbiological | 155197 | Insulin Like Growth Factor Binding Protein 3 | 10ug | $350 | 2021-12-16 | Buy | |
| Usbiological | 140834 | Insulin Like Growth Factor Binding Protein 3 | 200ul | $375 | 2021-12-16 | Buy | |
| Usbiological | I7661-16H | Insulin-Like Growth Factor Binding Protein 3 | 200ul | $568 | 2021-12-16 | Buy |
HUMAN IGFBP-3 Chemical Properties,Uses,Production
Uses
IGF-Binding Protein-3 human has been used to study its association with follicular fluid and subsequent effect on embryo development.
Biological Activity
IGFBP3 (insulin-like growth factor-binding protein 3) is involved in cell survival as well as cell death and tumorigenesis. Epigenetic changes in IGFBP3 affect non-small-cell lung cancer, hepatocellular carcinoma, ovarian cancer, skin cancer, urological cancers, breast cancer and gastric cancer. IGFBP3 is a primary growth inhibitor and can reverse the mitogenic functions of IGF-1 (insulin like growth factor 1) by inducing apoptosis.IGFBP-3 functions both in an IGF-dependent and independent manner. Its IGF-dependent roles involve endocrine function by delivering IGFs to target cells and activating downstream signaling. Meanwhile, its IGF-independent roles include interactions with extracellular matrix and plasma membrane proteins, as well as translocation into the cytoplasm and nucleus. The C-terminal domain has cell-penetrating abilities, enabling the generation of short peptides for intracellular delivery of drugs or genes.
HUMAN IGFBP-3 Preparation Products And Raw materials
Raw materials
Preparation Products
HUMAN IGFBP-3 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10357 | 58 |
| Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 9747 | 58 |
| Shanghai Yingxin Laboratory Equipment Co., Ltd. | 021-021-59178156 17002132182 | 3146474380@qq.com | China | 11603 | 58 |
| Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | sales@shzbio.com | China | 9966 | 58 |
| Biolab Reagents | 027-65279366 18108604356 | products@biolabreagent.com | China | 9868 | 58 |
| ACROBiosystems | 18514007688 | jiaxin.zhao@acrobiosystems.com | China | 1291 | 58 |
| ZSGB-BIO | 02-400-810-9781 400810978 | sales@zsbio.com | China | 2887 | 58 |
| OriGene Technologies, Inc | 01-1-888-267-4436 1-301-340-3188 | sales@origene.com | China | 672261 | 58 |
| Demeditec Diagnostics GmbH | 49-04371922-0 49431719220 | info@demeditec.de | China | 330 | 58 |
| Merck KGaA | (+86) 21 2033 8288 | sigmaname@qq.com | CHINA | 292394 | 58 |