2,4-DIETHYLPYRIDINE DICARBOXYLATE
- CAS No.
- 41438-38-4
- Chemical Name:
- 2,4-DIETHYLPYRIDINE DICARBOXYLATE
- Synonyms
- 2,4-DPD;Ai3-17897;Diethyl-2,4-pdc;2,4-Pdc diethyl ester;2,4-Pyridinedicarboxylic;DIETHYL 2,4-PYRIDINECARBOXYLATE;2,4-DIETHYLPYRIDINE DICARBOXYLATE;Diethyl 2,4-pyridinedicarboxylate;diethyl pyridine-2,4-dicarboxylate;diethyl 2,4-pyridinedicarboxylic acid
- CBNumber:
- CB1454066
- Molecular Formula:
- C11H13NO4
- Molecular Weight:
- 223.23
- MDL Number:
- MFCD00152168
- MOL File:
- 41438-38-4.mol
| Melting point | 31 °C |
|---|---|
| Boiling point | 330.9±22.0 °C(Predicted) |
| Density | 1.165±0.06 g/cm3(Predicted) |
| vapor pressure | 0.022Pa at 25℃ |
| storage temp. | 2-8°C |
| solubility | ≤50mg/ml in ethanol;20mg/ml in DMSO;30mg/ml in dimethyl formamide |
| pka | -0.69±0.10(Predicted) |
| form | Crystalline |
| color | White to Almost white |
| LogP | 1.92 at 20℃ and pH7.82 |
| Surface tension | 56.3mN/m at 1g/L and 19.7℃ |
| CAS DataBase Reference | 41438-38-4 |
| FDA UNII | 4SN4572M5S |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
| HS Code | 2933.39.9200 | |||||||||
| NFPA 704 |
|
2,4-DIETHYLPYRIDINE DICARBOXYLATE price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | D5518 | Diethyl 2,4-Pyridinedicarboxylate >97.0%(GC) | 41438-38-4 | 200mg | $62 | 2024-03-01 | Buy |
| TCI Chemical | D5518 | Diethyl 2,4-Pyridinedicarboxylate >97.0%(GC) | 41438-38-4 | 1g | $186 | 2024-03-01 | Buy |
| Cayman Chemical | 71200 | 2,4-DPD ≥98% | 41438-38-4 | 10mg | $19 | 2024-03-01 | Buy |
| Cayman Chemical | 71200 | 2,4-DPD ≥98% | 41438-38-4 | 25mg | $41 | 2024-03-01 | Buy |
| Cayman Chemical | 71200 | 2,4-DPD ≥98% | 41438-38-4 | 50mg | $78 | 2024-03-01 | Buy |
2,4-DIETHYLPYRIDINE DICARBOXYLATE Chemical Properties,Uses,Production
Biological Activity
2,4-dpd is a cell permeable, competitive inhibitor of the oxygen-sensing enzyme hif-α prolyl hydroxylase (hif-ph) [1].hypoxia-inducible factor (hif) is a transcription factor with a key role in cellular responses to hypoxia in a variety of organisms. the hif system plays an important role in angiogenesis, erythropoiesis, energy utilization, glucose/energy metabolism, tumour development, and ischaemic/hypoxic disease. genetic or pharmacological inactivation of the hif hydroxylases results in a constitutive activation of the hif pathway with little or even absent regulation by oxygen remaining. the oxygen-sensing enzyme hif-α prolyl hydroxylase catalyzes hydroxylation of specific prolyl and asparaginyl residues in the regulatory hif-α subunits [2].exposure to 2,4-dpd limited prolyl 4-hydroxylase activity in c. elegans., where their esters are hydrolyzed to form competitors of a -ketoglutarate. 2,4-dpd showed dramatic effects among the progeny. when exposed to a high level of 2,4-dpd (2.7 mm), all progeny died regardless of genotype of c. elegans. the dead embryos arrested at the twofold stage [1].
References
[1] friedman l, higgin j j, moulder g, et al. prolyl 4-hydroxylase is required for viability and morphogenesis in caenorhabditis elegans[j]. proceedings of the national academy of sciences, 2000, 97(9): 4736-4741.
[2] schofield c j, ratcliffe p j. signalling hypoxia by hif hydroxylases[j]. biochemical and biophysical research communications, 2005, 338(1): 617-626.
2,4-DIETHYLPYRIDINE DICARBOXYLATE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10310 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32063 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30241 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34553 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9640 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 5986 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9414 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24727 | 58 |
View Lastest Price from 2,4-DIETHYLPYRIDINE DICARBOXYLATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-04 | 2,4-DPD
41438-38-4
|
US $40.00 / mg | 99.74% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-04 | Diethyl 2,4-Pyridinedicarboxylate
41438-38-4
|
US $0.00-0.00 / g | 1g | 98.0% | 1kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-10-31 | Diethyl pyridine-2,4-dicarboxylate
41438-38-4
|
US $1.00-10.00 / kg | 0.10000000149011612kg | 98%+ | 1 ton | Shenzhen Nexconn Pharmatechs Ltd |
-
- 2,4-DPD
41438-38-4
- US $40.00 / mg
- 99.74%
- TargetMol Chemicals Inc.
-
- Diethyl 2,4-Pyridinedicarboxylate
41438-38-4
- US $0.00-0.00 / g
- 98.0%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Diethyl pyridine-2,4-dicarboxylate
41438-38-4
- US $1.00-10.00 / kg
- 98%+
- Shenzhen Nexconn Pharmatechs Ltd
41438-38-4(2,4-DIETHYLPYRIDINE DICARBOXYLATE)Related Search:
1of4