Fmoc-(R)-2-amino-3-hydroxy-3-methylbutanoic acid
- CAS No.
- 884880-39-1
- Chemical Name:
- Fmoc-(R)-2-amino-3-hydroxy-3-methylbutanoic acid
- Synonyms
- (R)-N-Fmoc-2-amino-3-hydroxy-3-methylbutanoic acid;N-Fmoc-3-hydroxy-D-valine;Fmoc-3-Methyl-D-threonine;(R)-N-Fmoc-β-Hydroxyvaline;(R)-Fmoc-b,b-dimethyl-serine;(R)-Fmoc-β-hydroxy-valine≥ 99% (HPLC);Fmoc-(R)-2-amino-3-hydroxy-3-methylbutanoic acid;(R)-2-(Fmoc-amino)-3-hydroxy-3-methylbutanoic Acid;N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-hydroxy-D-valine;D-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-hydroxy-
- CBNumber:
- CB1456358
- Molecular Formula:
- C20H21NO5
- Molecular Weight:
- 355.38
- MDL Number:
- MFCD02682577
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HazardClass | IRRITANT |
Fmoc-(R)-2-amino-3-hydroxy-3-methylbutanoic acid price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Chem-Impex | 29717 | (R)-Fmoc-β-hydroxy-valine ≥99%(HPLC) | 884880-39-1 | 25MG | $106.96 | 2026-05-19 | Buy |
| Chem-Impex | 29717 | (R)-Fmoc-β-hydroxy-valine ≥99%(HPLC) | 884880-39-1 | 100MG | $225.94 | 2026-05-19 | Buy |
| Chem-Impex | 29717 | (R)-Fmoc-β-hydroxy-valine ≥99%(HPLC) | 884880-39-1 | 250MG | $405.41 | 2026-05-19 | Buy |
| Chem-Impex | 29717 | (R)-Fmoc-β-hydroxy-valine ≥99%(HPLC) | 884880-39-1 | 1G | $1013.82 | 2026-05-19 | Buy |
| Chem-Impex | 29717 | (R)-Fmoc-β-hydroxy-valine ≥99%(HPLC) | 884880-39-1 | 5G | $4280.31 | 2026-05-19 | Buy |
Fmoc-(R)-2-amino-3-hydroxy-3-methylbutanoic acid Chemical Properties, Uses, Production
Chemical Properties
White powder
Synthesis
82911-69-1
288159-40-0
884880-39-1
GENERAL STEPS: (R)-N-Fmoc-2-amino-3-hydroxy-3-methylbutanoic acid was synthesized in the following steps: first, (R)-2-((tert-butoxycarbonyl)amino)-3-hydroxy-3-methylbutanoic acid was stripped of the Boc protecting group in a 1:1 trifluoroacetic acid/dichloromethane solution. Subsequently, the Fmoc protection reaction was carried out using 9-fluorenylmethyl-N-succinimidyl carbonate (Fmoc-OSu) and sodium bicarbonate (NaHCO3) in aqueous acetone solution. After completion of the reaction, the product was purified by silica gel column chromatography (eluent ratio of 1:1:98 methanol/acetic acid/chloroform). Finally, the purified product was freeze-dried from aqueous acetonitrile solution to afford the target compound in 78% yield.
References
[1] Patent: US2009/48161, 2009, A1. Location in patent: Page/Page column 40
Fmoc-(R)-2-amino-3-hydroxy-3-methylbutanoic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Fmoc-(R)-2-amino-3-hydroxy-3-methylbutanoic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| SINO High Goal Chemical Technology Co., Ltd. | 021-57646680 18306277365 | sunkai@chembiobanksh.com | China | 2039 | 55 |
| Shanghai GL Peptide Ltd. | +86-21-61263310 13764994101 | fisherwang@glschina.com | China | 8048 | 55 |
| BePharm Ltd | 400-685-9117 | market@bepharm.com | China | 15081 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Aikon International Limited | 025-58851090 13913916777 | sales01@aikonchem.com | China | 15947 | 58 |
| 3A Chemicals | 400-668-9898 | service@3achem.com | China | 20535 | 58 |
| Shanghai Jifeng Biotechnology Co., Ltd. | 021-61263377 15023907684 | 15800684150@163.com | China | 8000 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19904 | 58 |
| Binhai gill polypeptide co. LTD | 021-61263389 13524856427 | Joetang@glschina.com | China | 9927 | 58 |
