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Elenbecestat

CAS No.
1388149-39-0
Chemical Name:
Elenbecestat
Synonyms
Elenbecestat free base;2-Pyrazinecarboxamide, N-[3-[(4aS,5S,7aS)-2-amino-4a,5-dihydro-5-(trifluoromethyl)-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl]-5-(difluoromethyl)-
CBNumber:
CB14844751
Molecular Formula:
C19H15F6N5O2S
Molecular Weight:
491.41
MDL Number:
MOL File:
1388149-39-0.mol
Last updated:2023-03-31 09:12:57

Elenbecestat Properties

solubility Soluble in DMSO:80.0(Max Conc. mg/mL);182.88(Max Conc. mM)

Elenbecestat Chemical Properties,Uses,Production

Description

Elenbecestat,also known as E2609 is a BACE1 inhibitor. By inhibiting BACE, a key enzyme in the production of Aβ peptides, E2609 decreases the formation of these peptides which can aggregate into toxic oligomers and protofibrils and eventually form amyloid plaques in the brain. Elenbecestat has been shown to reduce Aβ levels in cerebrospinal fluid, was investigated in two global phase 3 studies in early AD.

Elenbecestat Preparation Products And Raw materials

Raw materials

Preparation Products

Elenbecestat Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9412 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 28118 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 12007 58
2-Pyrazinecarboxamide, N-[3-[(4aS,5S,7aS)-2-amino-4a,5-dihydro-5-(trifluoromethyl)-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl]-5-(difluoromethyl)- Elenbecestat free base 1388149-39-0 C19H15F6N5O2S