ChemicalBook >> CAS DataBase List >>Palbociclib Impurity I

Palbociclib Impurity I

CAS No.
2172256-78-7
Chemical Name:
Palbociclib Impurity I
Synonyms
6-Acetyl-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidine-2,7(3H,8H)-dione;Pyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione, 6-acetyl-8-cyclopentyl-5-methyl-;6-?Acetyl-?8-?cyclopentyl-?5-?methylpyrido[2,?3-?d]?pyrimidine-?2,?7(1H,?8H)?-?dione;6-Acetyl-8-cyclopentyl-2-hydroxy-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one (Palbociclib Impurity)
CBNumber:
CB14902426
Molecular Formula:
C15H17N3O3
Molecular Weight:
287.31
MDL Number:
MFCD31689659
MOL File:
2172256-78-7.mol
Last updated:2023-04-23 13:52:06

Palbociclib Impurity I Properties

Melting point >201°C (dec.)
Density 1.44±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
pka 10.09±0.60(Predicted)
form Solid
color Light Beige to Brown
FDA UNII HWX4G49JE4

Palbociclib Impurity I Chemical Properties,Uses,Production

Uses

6-?Acetyl-?8-?cyclopentyl-?5-?methylpyrido[2,?3-?d]?pyrimidine-?2,?7(1H,?8H)?-?dione is an impurity of Palbociclib (P139900), a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6 which may be useful in the treatment of breast cancer.

Palbociclib Impurity I Preparation Products And Raw materials

Raw materials

Preparation Products

Palbociclib Impurity I Suppliers

Global( 19)Suppliers
Supplier Tel Email Country ProdList Advantage
China National Standard Pharmaceutical Corporation Limited
+8615391658522 overseasales@yongstandards.com China 11922 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131957 58
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 7191 65
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9906 50
SHANGHAI FDC-CHEMICAL CO.,LTD 021-61469567 13482353728 sales@fdc-chemical.com China 16742 58
Shanghai Han-Xiang Chemical Co., Ltd. 15971444841 amber@biochempartner.com China 3061 58
SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD 0755-0755-0755-83725350 13380397412 3001280422@qq.com China 10005 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 info@synzest.com China 9286 58
Hubei Xinyang Medical Technology Co., Ltd 15347293736 15347293736 2853117764@qq.com China 8329 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 40037 58
6-Acetyl-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidine-2,7(3H,8H)-dione Pyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione, 6-acetyl-8-cyclopentyl-5-methyl- 6-?Acetyl-?8-?cyclopentyl-?5-?methylpyrido[2,?3-?d]?pyrimidine-?2,?7(1H,?8H)?-?dione 6-Acetyl-8-cyclopentyl-2-hydroxy-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one (Palbociclib Impurity) 2172256-78-7