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MORPHINE SULFATE NARCOTIC ANALGESIC

CAS No.
64-31-3
Chemical Name:
MORPHINE SULFATE NARCOTIC ANALGESIC
Synonyms
Capros;Avinza;Skenan;Kadian;Kapanol;NIH 0001;Oblioser;Oramorph;Relipain;Morphelan
CBNumber:
CB1497069
Molecular Formula:
C18H25NO8S
Molecular Weight:
415.458
MDL Number:
MFCD00069309
MOL File:
64-31-3.mol
Last updated:2023-05-04 17:34:41

MORPHINE SULFATE NARCOTIC ANALGESIC Properties

Melting point 250 °C
Flash point 11℃
storage temp. −20°C
CAS DataBase Reference 64-31-3
FDA UNII DY70C97N30
NCI Drug Dictionary Avinza
EPA Substance Registry System Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl-(5.alpha.,6.alpha.)-, sulfate (2:1) (64-31-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS06,GHS08
Signal word  Danger
Hazard statements  H225-H301-H311-H331-H370
Precautionary statements  P210-P260-P280-P301+P310-P311
Hazard Codes  F,T
Risk Statements  11-23/24/25-39/23/24/25
Safety Statements  7-16-36/37-45
RIDADR  UN 1230 3/PG 2
WGK Germany  1

MORPHINE SULFATE NARCOTIC ANALGESIC Chemical Properties,Uses,Production

Originator

Avinza,Aetna Inc.

Uses

Analgesic (narcotic).

Definition

ChEBI: Morphine sulfate is an alkaloid sulfate salt. It contains a morphine.

Manufacturing Process

Morphin was extracted from the plant vegetable (the poppy) by the mixture of water and methanol or the aqueous solution of potassium pyrosulfate. The precipitation of the morphin was carried out by addition to the extract the aqueous solution of sodium carbonate.
Morphin can be obtained from the extract by using the cation exchanger.
Free base of morphin was transformated to the sulfate salt.

brand name

Astramorph (AstraZeneca); Avinza (Ligand); Depodur (Skyepharma); Duramorph (Baxter Healthcare); Infumorph (Baxter Healthcare); Kadian (Alpharma); Ms Contin (Purdue Frederick); Oramorph (Xanodyne).

Therapeutic Function

Narcotic analgesic, Sedative

Safety Profile

Poison by subcutaneous, intravenous, intraperitoneal, and intramuscular routes. Moderately toxic by ingestion and parenteral routes. An experimental teratogen. Experimental reproductive effects. Mutation data reported. Used as a narcotic. Abuse leads to habituation or addiction. When heated to decomposition it emits very toxic fumes of NOx and SOx.

MORPHINE SULFATE NARCOTIC ANALGESIC Preparation Products And Raw materials

Raw materials

Preparation Products

Morphine sulfate salt pentahydrate,Morphine hemi[sulfate pentahydrate] Morphine sulfate salt solution MORPHINE SULFATE METHANOL SOLUTION Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl- (5.alpha.,6.alpha.)-, sulfate (2:1) (salt) Avinza Capros Kapanol Morphelan Morphinan-3,6a-diol, 7,8-didehydro-4,5a-epoxy-17-methyl-, sulfate (2:1) (salt) (8CI) Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl- (5a,6a)-, sulfate (2:1) (salt) (9CI) Moscontin MST Continus NIH 0001 NIH 10753 NSC 11441 Oblioser Oramorph Relipain Skenan Controlled-release morphine sulfate Kadian 6-diol,7,8-didehydro-4,5-epoxy-17-methyl-(5alpha,6alpha)-morphinan-sulf ate(2:1)(salt) l-morphinesulfate MORPHINE SULFATE NARCOTIC ANALGESIC 6-alpha-diol,7,8-didehydro-4,5-alpha-epoxy-17-methyl-morphinan-sulfate Mouse Anti-Morphine(2F11) antibody Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl- (5α,6α)-, sulfate (2:1) 64-31-3 2C17H19NO3H2O4S C34H38N2O6H2SO4