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IDH1 Inhibitor 2
- CAS No.
- 2244895-42-7
- Chemical Name:
- IDH1 Inhibitor 2
- Synonyms
- H1 Inhibitor 2;IDH1 Inhibitor 2;IDH1 Inhibitor 2,IDH-1 Inhibitor 2;Benzo[h]quinazoline-9-carbonitrile, 5,6,6a,7,8,10a-hexahydro-7-methyl-8-oxo-10a-phenyl-2-(phenylamino)-, (6aS,7S,10aR)-
- CBNumber:
- CB15821456
- Molecular Formula:
- C26H22N4O
- Molecular Weight:
- 406.48
- MDL Number:
- MFCD32067987
- MOL File:
- 2244895-42-7.mol
Last updated:2024-07-02 08:55:01
IDH1 Inhibitor 2 Chemical Properties,Uses,Production
Description
IDH1 Inhibitor 2 is a potent IDH1 inhibitor via a direct covalent modification of His315, with an IC50 of 110 nM[1]. IC50: 110 nM (IDH1)[1].
References
[1]. Jakob CG, et al. Novel Modes of Inhibition of Wild-Type Isocitrate Dehydrogenase 1 (IDH1): Direct Covalent Modification of His315. J Med Chem. 2018 Aug 9;61(15):6647-6657.
IDH1 Inhibitor 2 Preparation Products And Raw materials
Raw materials
Preparation Products
IDH1 Inhibitor 2 Suppliers
Global( 5)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 23963 | 58 |
| Shanghai Yiyan Biotechnology Co. , Ltd. | 021-69985186 13611928337 | 3427709316@qq.com | China | 7980 | 58 |
| Nantong Hanfang Biotechnology Co. , Ltd. | 18616537568 | hanfangpharma@126.com | China | 30968 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Aladdin Scientific | 58 |
| TargetMol Chemicals Inc. | 58 |
| Shanghai Yiyan Biotechnology Co. , Ltd. | 58 |
| Nantong Hanfang Biotechnology Co. , Ltd. | 58 |
IDH1 Inhibitor 2
H1 Inhibitor 2
IDH1 Inhibitor 2,IDH-1 Inhibitor 2
Benzo[h]quinazoline-9-carbonitrile, 5,6,6a,7,8,10a-hexahydro-7-methyl-8-oxo-10a-phenyl-2-(phenylamino)-, (6aS,7S,10aR)-
2244895-42-7