C26 Sphingomyelin (d18:1/26:0)
- CAS No.
- 221097-57-0
- Chemical Name:
- C26 Sphingomyelin (d18:1/26:0)
- Synonyms
- C26 Sphingomyelin (d18:1/26:0);(7S)-4-hydroxy-7-[(1R,2E)-1-hydroxy-2-hexadecen-1-yl]-N,N,N-trimethyl-9-oxo-3,5-dioxa-8-aza-4-phosphatetratriacontan-1-aminium, 4-oxide, inner salt
- CBNumber:
- CB16198089
- Molecular Formula:
- C49H99N2O6P
- Molecular Weight:
- 843.31
- MDL Number:
- MOL File:
- 221097-57-0.mol
C26 Sphingomyelin (d18:1/26:0) Chemical Properties,Uses,Production
Definition
ChEBI: N-hexacosanoylsphingosine-1-phosphocholine is a sphingomyelin d18:1 in which the ceramide N-acyl group is specified as hexacosanoyl. It has a role as a mouse metabolite. It is a sphingomyelin 44:1 and a sphingomyelin d18:1. It is functionally related to a hexacosanoic acid.
Biological Activity
C26 Sphingomyelin is a sphingolipid that has been found in serum and cell or brain extracts.1,2,3 C26 sphingomyelin levels are increased in the serum of patients with hemophagocytic lymphohistiocytosis, an inflammatory condition characterized by excessive immune activation.3 C26 sphingomyelin has been used a component of monolayers to study the influence of sphingomyelin acyl chain length on sphingomyelin-sterol interactions.4 [Matreya, LLC.]
References
1.Wang, J.-R., Zhang, H., Yau, L.D., et al.Improved sphingolipidomic approach based on ultra-high performance liquid chromatography and multiple mass spectrometries with application to cellular neurotoxicityAnal. Chem.86(12)5688-5696(2014) 2.Willmann, J., Mahlstedt, K., Leibfritz, D., et al.Characterization of sphingomyelins in lipid extracts using a HPLC-MS-offline-NMR methodAnal. Chem.79(11)4188-4191(2007) 3.Jenkins, R.W., Clarke, C.J., Lucas, J.T., Jr., et al.Evaluation of the role of secretory sphingomyelinase and bioactive sphingolipids as biomarkers in hemophagocytic lymphohistiocytosisAm. J. Hematol.88(11)E265-E272(2013) 4.Li, X.M., Momsen, M.M., Brockman, H.L., et al.Sterol structure and sphingomyelin acyl chain length modulate lateral packing elasticity and detergent solubility in model membranesBiophys. J.85(6)3788-3801(2003)
C26 Sphingomyelin (d18:1/26:0) Preparation Products And Raw materials
Raw materials
Preparation Products
C26 Sphingomyelin (d18:1/26:0) Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ChemeGen 中国 | 18818260767 | sales@chemegen.com | China | 6975 | 58 |
Hubei Aiputi Bioengineering Co., Ltd. | 17762444226 | d17762444226@163.com | China | 2402 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8739 | 58 |
SHANGHAI ZZBIO CO., LTD. | 13916577892 19921389125 | tech@zzbioco.com | China | 12064 | 58 |
Supplier | Advantage |
---|---|
ChemeGen 中国 | 58 |
Hubei Aiputi Bioengineering Co., Ltd. | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
SHANGHAI ZZBIO CO., LTD. | 58 |