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7-Azaindole

7-Azaindole Structure
7-Azaindole structure
CAS No.
271-63-6
Chemical Name:
7-Azaindole
Synonyms
1H-PYRROLO[2,3-B]PYRIDINE;NSC 67063;NSC 77951;7-azindole;7-AZAINDOLE;7-Azaindole99%;7-Dideazapurine;7-Azaindole,98%;7-AZAINDOLE 98%;7-Aza-7H-indole
CBNumber:
CB1664663
Molecular Formula:
C7H6N2
Molecular Weight:
118.14
MDL Number:
MFCD00005606
MOL File:
271-63-6.mol
MSDS File:
SDS
Last updated:2024-11-05 11:59:05
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7-Azaindole Properties

Melting point 105-107 °C (lit.)
Boiling point 270 °C (753.1004 mmHg)
Density 1.1151 (rough estimate)
refractive index 1.5500 (estimate)
Flash point 270°C
storage temp. Sealed in dry,Room Temperature
solubility Chloroform, Methanol
pka 7.69±0.20(Predicted)
form Powder
color White to off-white
BRN 109667
InChIKey MVXVYAKCVDQRLW-UHFFFAOYSA-N
CAS DataBase Reference 271-63-6(CAS DataBase Reference)
FDA UNII QX4465NR9T
NIST Chemistry Reference 1H-Pyrrolo[2,3-b]pyridine(271-63-6)
EPA Substance Registry System 1H-Pyrrolo[2,3-b]pyridine (271-63-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard Codes  Xi,Xn
Risk Statements  36-41-37/38-22
Safety Statements  39-26-36/37/39
WGK Germany  3
RTECS  UY8710000
HazardClass  IRRITANT
HS Code  29339990
NFPA 704
1
2 0

7-Azaindole price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A95502 7-Azaindole 98% 271-63-6 1g $47.8 2024-03-01 Buy
TCI Chemical P1117 1H-Pyrrolo[2,3-b]pyridine >98.0%(GC)(T) 271-63-6 5g $27 2024-03-01 Buy
TCI Chemical P1117 1H-Pyrrolo[2,3-b]pyridine >98.0%(GC)(T) 271-63-6 25g $126 2024-03-01 Buy
Alfa Aesar L07983 7-Azaindole, 98% 271-63-6 1g $25.65 2024-03-01 Buy
Alfa Aesar L07983 7-Azaindole, 98% 271-63-6 5g $66.65 2024-03-01 Buy
Product number Packaging Price Buy
A95502 1g $47.8 Buy
P1117 5g $27 Buy
P1117 25g $126 Buy
L07983 1g $25.65 Buy
L07983 5g $66.65 Buy

7-Azaindole Chemical Properties,Uses,Production

Chemical Properties

Brown-Cyrstalline Solid

Uses

7-Azaindole is imidazolinone derivatives as CGRP receptor antagonists used in the treatment.
A heterocyclic molecule that can be utilized as a pharmaceutical building block.
Starting material in a recent synthesis of azaserotonin.

Application

7-Azaindole is a heterocyclic organic compound, which is an organic synthesis intermediate and a pharmaceutical intermediate. It is the core structure of many drugs, such as antitumor drugs, dopamine D4 receptors, p38 kinase inhibitors, thrombin inhibitors, etc.

Preparation

Synthesis of 7-azaindole: in a single-necked flask, add 2.0 g of 2-amino-3-methylpyridine and 2.5 g of N-Methylformanilide into 40 mL of dichloromethane, and add 3.15 g of PCl with stirring under an ice-water bath. After 4 hours of reaction, the reaction system was slowly poured into 40 mL of ammonia water, and the insoluble matter was removed by suction filtration. The organic layer was separated, washed twice with water, dried over anhydrous sodium sulfate, and evaporated to dryness to obtain 2.91 g of 7-azaindole as a pale yellow solid, with a yield of 70%.

Definition

ChEBI: 1H-pyrrolo[2,3-b]pyridine is a pyrrolopyridine.

Purification Methods

Recrystallise it repeatedly from EtOH, then sublime it in a vacuum [Tokumura et al. J Am Chem Soc 109 1346 1987]. The N-acetate has m 65-66o (from *C6H6), and the picrate has m 232-233o (from Me2CO) [Clemo & Swan J Chem Soc 603 1945, Beilstein 23 III/IV 1105.]

7-Azaindole Preparation Products And Raw materials

Raw materials

Preparation Products

2-(2,3-DIHYDRO-1BENZENESULFONYL-PYRROLO[2,3-B]PYRIDIN-3-YL)ETHANAMINE 6-BROMO-1H-PYRROLO[2,3-B]PYRIDINE 4-IODO-7-AZAINDOLE 1H-Pyrrolo[2,3-b]pyridine, 4-nitro-, 7-oxide 4-Bromo-7-azaindole
4-Chloro-7-azaindole 7-OXIDE-7-AZAINDOLE 5-BROMO-1H-PYRROLO[2 , 3-B]PYRIDIN-2(3H)-ONE 5-Bromo-7-azaindole 2-(2,3-DIHYDRO-1-BENZENESULFONYL-PYRROLO[2,3-B]PYRIDIN-3-YL)ACETONITRILE
4-CYANO-7-AZAINDOLE 1,7-DIDEAZAADENINE 6-CHLORO-1H-PYRROLO[2,3-B]PYRIDINE 3-Bromo-7-azaindole 1H-PYRROLO[2,3-B]PYRIDINE, 4-NITRO-
2-(2,9-diazabicyclo[4.3.0]nona-2,4,7,10-tetraen-7-yl)ethanamine 4-HYDROXYMETHYL-7-AZAINDOLE 5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one 4-CHLORO-5-NITRO-1-(PHENYLSULFONYL)-1H-PYRROLO[2,3-B]PYRIDINE 1-(Benzenesulfonyl)-3-bromo-1H-pyrrolo[2,3-b]pyridine

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7-Azaindole Suppliers

Global( 677)Suppliers
Supplier Tel Email Country ProdList Advantage
Terma Medicare India Pvt.,Ltd 		+8613916485955 shivshanghai@yahoo.com India 150 58
Hebei Weibang Biotechnology Co., Ltd 		+8615531157085 abby@weibangbio.com China 8810 58
Hebei Mojin Biotechnology Co., Ltd 		+86 13288715578 +8613288715578 sales@hbmojin.com China 12839 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-13131129325 sales1@chuanghaibio.com China 5892 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20286 58
hebei hongtan Biotechnology Co., Ltd 		+86-86-1913198-3935 +8617331935328 sales03@chemcn.cn China 970 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29791 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1803 55
Hangzhou FandaChem Co.,Ltd. 		+8615858145714 FandaChem@Gmail.com China 9206 55
Supplier Advantage
Terma Medicare India Pvt.,Ltd 		58
Hebei Weibang Biotechnology Co., Ltd 		58
Hebei Mojin Biotechnology Co., Ltd 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Henan Fengda Chemical Co., Ltd 		58
hebei hongtan Biotechnology Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Time Chemicals CO., Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55

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View Lastest Price from 7-Azaindole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
7-Azaindole pictures 2024-11-28 7-Azaindole
271-63-6
 US $30.00 / kg 1kg 98% 3000kg hebei hongtan Biotechnology Co., Ltd
7-Azaindole pictures 2024-11-28 7-Azaindole
271-63-6
 US $2.00 / KG 1KG 99% 100mt/year Jinan Finer Chemical Co., Ltd
7-Azaindole pictures 2024-11-05 7-Azaindole
271-63-6
 US $100.00-20700.00 / KG 1g 98%min 2000tons Shaanxi Dideu Medichem Co. Ltd
  • 7-Azaindole pictures
  • 7-Azaindole
    271-63-6
  • US $30.00 / kg
  • 98%
  • hebei hongtan Biotechnology Co., Ltd
  • 7-Azaindole pictures
  • 7-Azaindole
    271-63-6
  • US $2.00 / KG
  • 99%
  • Jinan Finer Chemical Co., Ltd
  • 7-Azaindole pictures
  • 7-Azaindole
    271-63-6
  • US $100.00-20700.00 / KG
  • 98%min
  • Shaanxi Dideu Medichem Co. Ltd

7-Azaindole Spectrum

7-Azaindole(271-63-6)MS7-Azaindole(271-63-6)1HNMR7-Azaindole(271-63-6)13CNMR7-Azaindole(271-63-6)IR17-Azaindole(271-63-6)IR27-Azaindole(271-63-6)Raman

271-63-6(7-Azaindole )Related Search:

Pyridine Indometacin Indoline Indole-3-butyric acid Indole-3-acetic acid
7-Benzyloxyindole 7-Fluoroindole 7-Aminoindole 7-Fluorooxindole 7-FLUOROINDOLINE
6-Azaindole 1H-Pyrrolo[3,2-c]pyridine, 5-Azaindole 5-BROMO AZAINDOLE 4-Azaindole 5-Chloro-7-azaindole
2-AMINO-9H-PYRIDO[2,3-B]INDOLE 4,7-Diazaindole 7-Chloro-6-azaindole, 97%

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1,7-Diaza-1H-indene 7-Aza-7H-indole 7-Aza-1-pyrindine 7H-Pyrrolo[2,3-b]pyridine Pyrrolo(2,3-b)pyridine 7-AZAINDOLE CRYSTALLINE 7-AZAINDOLE 98% 7-Azaindole99% 7-Azaindole,98% 7-Dideazapurine 7-Azaindole, 98% 5GR NSC 67063 NSC 77951 7-AZAINDOLE FOR SYNTHESIS 1 G 7-Azaindole SynonyMs 1H-Pyrrolo[2,3-b]pyridine 7-Azaindole, 97+% 1H-PYRROLO[2,3-B]PYRIDINE, HYDRATE 7-AZAINDOLE 7-AZAINDOLE, 1H-PYRROLO[2,3,B]PYRIDINE TIMTEC-BB SBB004295 1 H-PYRROLO[2,3:B]PYRIDINE 1H-PYRROLO[2,3]PYRIDINE 1,7-Diazaindene 1,7-Dideazapurine 1H-Pyrrolo[2,3-b]pyridin 1H-Pyrrolo[2,3-b]pyridine> 7-Azaindole 7-Aza-7H-indole 1H-PYRROLO[2,3-B]PYRIDINE 7-Azaindole CAS NO.271-63-6 1H-Pyrrolo[2,3-b]pyridine (6CI, 8CI, 9CI, ACI) Atogepant Impurity 8 7-azindole 7-Azaindole 97.5% For Synthesis 271-63-6 205-981-0 Building Blocks Heterocyclic Building Blocks Indoles blocks IndolesOxindoles Heterocycles Indole Derivatives Pharmaceutical intermediate Heterocycles series Indole Heterocyclic Compounds Indole Series Heterocycle-Indole series Heterocycle-Pyridine series buildingblock Halogenated Heterocycles ,Thiazoles Aromatics Intermediates & Fine Chemicals Pharmaceuticals