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ChemicalBook >> CAS DataBase List >>5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE

5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE

5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Structure
5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE structure
CAS No.
27406-31-1
Chemical Name:
5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE
Synonyms
MHY-1685;IFLAB-BB F1208-0006;5-(4-HYDROXYBENZYLIDENE)BARBITURIC ACID;5-(4-HYDROXYBENZYLIDENE)BARBUTIRIC ACID;5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE;5-(4-HYDROXYBENZYLIDENE)PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE;5-(4-hydroxyphenyl)methylenehexahydropyrimidine-2,4,6-trione;2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(4-hydroxyphenyl)methylene]-;MHY-1685,MHY1685,MHY 1685,inhibit,mTOR,Inhibitor,Mammalian target of Rapamycin
CBNumber:
CB1669325
Molecular Formula:
C11H8N2O4
Molecular Weight:
232.19
MDL Number:
MFCD00117979
MOL File:
Mol file
MSDS File:
SDS
Last updated:2024-11-19 20:33:22
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5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Properties

storage temp. Store at -20°C
solubility DMSO : 62.5 mg/mL (269.18 mM; Need ultrasonic)
form Solid
color Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H319-H301
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501-P264-P280-P305+P351+P338-P337+P313P

5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S135925 5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Aldrich 27406-31-1 50mg $29.8 2024-03-01 Buy
Product number Packaging Price Buy
S135925 50mg $29.8 Buy

5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Chemical Properties,Uses,Production

Biological Activity

MHY-1685, a novel mammalian target of rapamycin (mTOR) inhibitor, provides opportunities to improve hCSC-based myocardial regeneration.

References

[1]. Park JH, et al. Human cardiac stem cells rejuvenated by modulating autophagy with MHY-1685 enhance the therapeutic potential for cardiac repair. Exp Mol Med. 2021 Sep;53(9):1423-1436.

5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE synthesis

67-52-7
123-08-0
27406-31-1
Synthesis of 5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE from Barbituric acid and 4-Hydroxybenzaldehyde

5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Preparation Products And Raw materials

Raw materials

Preparation Products

5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Suppliers

Global( 26)Suppliers
Supplier Tel Email Country ProdList Advantage
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30240 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38632 58
Nanjing Chalf-Pharm Technology Co., Ltd. 025-57018978 18251899859 sales@chalf-pharm.com China 5805 50
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4512 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Shanghai SuperLan Chemcial Technique Centre 021-2022843681 15618226720 lucy@atkchemical.com China 10169 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9409 58
Shandong Jirun Biomedical Technology Co., Ltd. 0539-0539-8613587 17661611089 2639273505@qq.com China 170 58
Supplier Advantage
Chongqing Chemdad Co., Ltd 		58
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
TargetMol Chemicals Inc. 		58
Nanjing Chalf-Pharm Technology Co., Ltd. 50
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai SuperLan Chemcial Technique Centre 58
DC Chemicals 58
Shandong Jirun Biomedical Technology Co., Ltd. 58

View Lastest Price from 5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
MHY-1685 pictures 2024-11-19 MHY-1685
27406-31-1
 US $29.00 / mg 98.44% 10g TargetMol Chemicals Inc.
  • MHY-1685 pictures
  • MHY-1685
    27406-31-1
  • US $29.00 / mg
  • 98.44%
  • TargetMol Chemicals Inc.
IFLAB-BB F1208-0006 5-(4-HYDROXYBENZYLIDENE)BARBITURIC ACID 5-(4-HYDROXYBENZYLIDENE)PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE 5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE 5-(4-HYDROXYBENZYLIDENE)BARBUTIRIC ACID 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(4-hydroxyphenyl)methylene]- 5-(4-hydroxyphenyl)methylenehexahydropyrimidine-2,4,6-trione MHY-1685 MHY-1685,MHY1685,MHY 1685,inhibit,mTOR,Inhibitor,Mammalian target of Rapamycin 27406-31-1