DICLOFENAC-D4
- CAS No.
- 153466-65-0
- Chemical Name:
- DICLOFENAC-D4
- Synonyms
- D4-Diclofenac;DICLOFENAC-D4;[2H4]-Diclofenac;Diclofenac-D4 (Major);DICLOFENAC-D4 (PHENYL-D4);2-((2,6-Dichlorophenyl)aminobenzeneacetic Acid-d4,;2-[2,3,4,5-tetradeuterio-6-(2,6-dichloroanilino)phenyl]aceticaci;2-[2,3,4,5-tetradeuterio-6-(2,6-dichloroanilino)phenyl]acetic acid;Diclofenac D4Q: What is Diclofenac D4 Q: What is the CAS Number of Diclofenac D4 Q: What is the storage condition of Diclofenac D4 Q: What are the applications of Diclofenac D4
- CBNumber:
- CB1677920
- Molecular Formula:
- C14H11Cl2NO2
- Molecular Weight:
- 296.15
- MDL Number:
- MFCD06658788
- MOL File:
- 153466-65-0.mol
| Melting point | 157-159°C |
|---|---|
| storage temp. | -20°C Freezer |
| solubility | DMSO: 35 mg/ml,Ethanol: 35 mg/ml,PBS (pH 7.2): 6 mg/ml |
| form | A solid |
| Water Solubility | Water: 50 mg/ml |
| CAS DataBase Reference | 153466-65-0 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| NFPA 704 |
|
DICLOFENAC-D4 price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 19072 | Diclofenac-d4 ≥99% | 153466-65-0 | 500μg | $135 | 2024-03-01 | Buy |
| Cayman Chemical | 19072 | Diclofenac-d4 ≥99% | 153466-65-0 | 1mg | $241 | 2024-03-01 | Buy |
| TRC | D436452 | Diclofenac-d4 | 153466-65-0 | 10mg | $825 | 2021-12-16 | Buy |
| TRC | D436452 | Diclofenac-d4 | 153466-65-0 | 1mg | $195 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | RDL0007267 | DICLOFENAC-D4 95.00% | 153466-65-0 | 10MG | $1732.5 | 2021-12-16 | Buy |
DICLOFENAC-D4 Chemical Properties,Uses,Production
Description
Diclofenac-d4 is intended for use as an internal standard for the quantification of diclofenac (Item Nos. 70680 | 22983) by GC- or LC-MS. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 0.9-2.7 and 1.5-20 μM, for human COX-1 and COX-2, respectively). It is also an active metabolite of diclofenac methyl ester and diclofenac amide . Diclofenac inhibits release of arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) induced by A23187 in isolated rat peritoneal neutrophils and macrophages (IC50s = 60 and 10 μM, respectively). Transdermal administration of diclofenac inhibits carrageenan-induced paw edema in rats. Formulations containing diclofenac have been used in the treatment of pain associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
Chemical Properties
Off-White Crystalline Solid
Uses
Labeled Diclofenac, a nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor. 92% overall isotopic purity. A representative lot was 75% d4, 23% d3 and 2 % d2
Uses
Labelled Diclofenac, a nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor.
Uses
Labelled Diclofenac is a known nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor.
DICLOFENAC-D4 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| PureChemland Co.,Ltd. | 19150123681 | 3848291069@qq.com | China | 3099 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| S.Z. PhyStandard Bio-Tech. Co., Ltd. | 0755-4000505016 13380397412 | 3001272453@qq.com | China | 4979 | 50 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-400-6206333 18521732826 | market@aladdin-e.com | China | 25014 | 65 |
| Cato Research Chemicals Inc. | 020-81960175 | min.he@cato-chem.com | China | 1958 | 55 |
| ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 17993 | 56 |
| Shanghai Kewel Chemical Co., Ltd. | 021-64609169 18901607656 | greensnown@163.com | China | 9911 | 50 |
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